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Yan Helen Yan
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Year
Limitations and opportunities of technologies for the analysis of cell-free DNA in cancer diagnostics
P Song, LR Wu, YH Yan, JX Zhang, T Chu, LN Kwong, AA Patel, ...
Nature biomedical engineering 6 (3), 232-245, 2022
742022
Modular probes for enriching and detecting complex nucleic acid sequences
JS Wang*, YH Yan*, DY Zhang
Nature chemistry 9 (12), 1222, 2017
372017
Low-level parental somatic mosaic SNVs in exomes from a large cohort of trios with diverse suspected Mendelian conditions
T Gambin, Q Liu, JA Karolak, CM Grochowski, NG Xie, LR Wu, YH Yan, ...
Genetics in Medicine 22 (11), 1768-1776, 2020
322020
Selective multiplexed enrichment for the detection and quantitation of low-fraction DNA variants via low-depth sequencing
P Song, SX Chen, YH Yan, A Pinto, LY Cheng, P Dai, AA Patel, DY Zhang
Nature biomedical engineering 5 (7), 690-701, 2021
312021
Confirming putative variants at≤ 5% allele frequency using allele enrichment and Sanger sequencing
YH Yan, SX Chen, LY Cheng, AY Rodriguez, R Tang, K Cabrera, ...
Scientific reports 11 (1), 11640, 2021
252021
RNA Scaffold: Designed to Co-localize Enzymes.
ZTGEM 2012), M Chen
Methods in molecular biology (Clifton, NJ) 1316, 105-112, 2014
4*2014
Detecting and quantitating low fraction DNA variants with low-depth sequencing
P Song, SX Chen, YH Yan, A Pinto, LY Cheng, P Dai, AA Patel, DY Zhang
bioRxiv, 2020.04. 26.061747, 2020
32020
925P Analytical performance of a next-generation sequencing (NGS) assay kit for assessing homologous recombination deficiency (HRD) from solid tumor samples
L Liu, K Roessler, S Bilke, Y Ding, D Erlandson, Y Fu, B Hariharan, S Katz, ...
Annals of Oncology 33, S969, 2022
12022
Encoding multiple digital DNA signals in a single analog channel
YH Yan, DY Zhang, LR Wu
Nucleic Acids Research 48 (11), e65-e65, 2020
12020
Microsatellite Instability Detection in Clinical Cancer Samples: A Multiplex qPCR Approach without Matching Normal Samples
W Chen*, YH Yan*, B Young, A Pinto, Q Jiang, N Song, W Yao, DY Zhang, ...
medRxiv, 2023
2023
High sensitivity detection of microsatellite loci by blocker displacement amplification with multiple blockers and its use in microsatellite instability detection
Y Yan
US Patent US20220298564A1, 2022
2022
High sensitivity qPCR microsatellite instability detection in FFPE tissue
YH Yan, B Young, Z Wang, A Yaseen, A Pinto, D Zhang
Cancer Research 82 (12_Supplement), 2806-2806, 2022
2022
Molecular hybridization probes for complex sequence capture and analysis
D Zhang, J Wang, Y Yan
WO Patent US20200080136A1, 2020
2020
Symbolic Sequencing of DNA and RNA via sequence encoding
DY Zhang, Y Yan
WO Patent WO2019046768A1, 2019
2019
Rationally Designed Hybridization Systems for Nucleic Acid Diagnostics and Sequence Analysis
YH Yan
Rice University, 2019
2019
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Articles 1–15