Expanding the genetic architecture of nicotine dependence and its shared genetics with multiple traits BC Quach, MJ Bray, NC Gaddis, M Liu, T Palviainen, CC Minica, S Zellers, ... Nature communications 11 (1), 5562, 2020 | 100 | 2020 |
DeFCoM: analysis and modeling of transcription factor binding sites using a motif-centric genomic footprinter B Quach, TS Furey Bioinformatics 33 (7), 956-963, 2017 | 40 | 2017 |
Integrative QTL analysis of gene expression and chromatin accessibility identifies multi-tissue patterns of genetic regulation GR Keele, BC Quach, JW Israel, GA Chappell, L Lewis, A Safi, JM Simon, ... PLoS genetics 16 (1), e1008537, 2020 | 39 | 2020 |
Multi-trait genome-wide association study of opioid addiction: OPRM1 and beyond N Gaddis, R Mathur, J Marks, L Zhou, B Quach, A Waldrop, O Levran, ... Scientific reports 12 (1), 16873, 2022 | 34 | 2022 |
Correcting nucleotide-specific biases in high-throughput sequencing data JR Wang, B Quach, TS Furey BMC bioinformatics 18, 1-10, 2017 | 26 | 2017 |
Genome-wide DNA methylation differences in nucleus accumbens of smokers vs. nonsmokers CA Markunas, SA Semick, BC Quach, R Tao, A Deep-Soboslay, ... Neuropsychopharmacology 46 (3), 554-560, 2021 | 21 | 2021 |
Epigenome‐wide analysis uncovers a blood‐based DNA methylation biomarker of lifetime cannabis use CA Markunas, DB Hancock, Z Xu, BC Quach, F Fang, DP Sandler, ... American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 2019 | 21 | 2019 |
Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing F Chen, X Wang, SK Jang, BC Quach, JD Weissenkampen, ... Nature genetics 55 (2), 291-300, 2023 | 19 | 2023 |
Chromatin architecture in addiction circuitry identifies risk genes and potential biological mechanisms underlying cigarette smoking and alcohol use traits NYA Sey, B Hu, M Iskhakova, S Lee, H Sun, N Shokrian, G Ben Hutta, ... Molecular psychiatry 27 (7), 3085-3094, 2022 | 19 | 2022 |
Strategies for cellular deconvolution in human brain RN A sequencing data [version 1; peer review: awaiting peer OA Sosina, MN Tran, KR Maynard, R Tao, MA Taub, K Martinowich, ... | 13* | 2021 |
Convergence of case-specific epigenetic alterations identify a confluence of genetic vulnerabilities tied to opioid overdose O Corradin, R Sallari, AT Hoang, BS Kassim, G Ben Hutta, L Cuoto, ... Molecular psychiatry 27 (4), 2158-2170, 2022 | 11 | 2022 |
Integration of evidence across human and model organism studies: A meeting report RHC Palmer, EC Johnson, H Won, R Polimanti, M Kapoor, A Chitre, ... Genes, Brain and Behavior 20 (6), e12738, 2021 | 10 | 2021 |
The evolution and putative function of phosducin-like proteins in the malaria parasite Plasmodium C Putonti, B Quach, RL Kooistra, SM Kanzok Infection, Genetics and Evolution 13, 49-55, 2013 | 3 | 2013 |
Evaluating 17 methods incorporating biological function with GWAS summary statistics to accelerate discovery demonstrates a tradeoff between high sensitivity and high positive … A Moore, JA Marks, BC Quach, Y Guo, LJ Bierut, NC Gaddis, DB Hancock, ... Communications Biology 6 (1), 1199, 2023 | 2* | 2023 |
Identifying novel gene dysregulation associated with opioid overdose death: A meta-analysis of differential gene expression in human prefrontal cortex JK Carter, BC Quach, C Willis, MS Minto, DB Hancock, J Montalvo-Ortiz, ... medRxiv, 2024 | 1 | 2024 |
Identifying compounds to treat opiate use disorder by leveraging multi-omic data integration and multiple drug repurposing databases. JK Stratford, MU Carnes, C Willis, MS Minto, L Elnimeiry, R Mathur, ... medRxiv, 2024.01. 17.24301329, 2024 | 1 | 2024 |
Gene expression differences associated with alcohol use disorder in human brain C Willis, JD White, MS Minto, BC Quach, S Han, R Tao, JH Shin, ... medRxiv, 2024.01. 20.24301386, 2024 | | 2024 |
Alcohol Use Disorder-Associated DNA Methylation in the Nucleus Accumbens and Dorsolateral Prefrontal Cortex JD White, MS Minto, C Willis, BC Quach, S Han, R Tao, A Deep-Soboslay, ... medRxiv, 2024.01. 17.23300238, 2024 | | 2024 |
Gene dysregulation among virally suppressed people living with HIV links to non-AIDS defining cancer pathways BC Quach, E Earley, L Zhou, C Willis, JA Marks, JK Stratford, F Fang, ... medRxiv, 2024.01. 03.24300792, 2024 | | 2024 |
Multi-omic network analysis identifies dysregulated neurobiological pathways in opioid addiction KA Sullivan, D Kainer, M Lane, M Cashman, JI Miller, MR Garvin, ... medRxiv, 2024.01. 04.24300831, 2024 | | 2024 |