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Jan Molenaar
Jan Molenaar
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Verified email at prinsesmaximacentrum.nl
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Cited by
Year
The landscape of genomic alterations across childhood cancers
SN Gröbner, BC Worst, J Weischenfeldt, I Buchhalter, K Kleinheinz, ...
Nature 555 (7696), 321-327, 2018
12592018
Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes
JJ Molenaar, J Koster, DA Zwijnenburg, P Van Sluis, LJ Valentijn, ...
Nature 483 (7391), 589-593, 2012
9302012
Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations
T Rausch, DTW Jones, M Zapatka, AM Stütz, T Zichner, J Weischenfeldt, ...
Cell 148 (1), 59-71, 2012
9132012
Relapsed neuroblastomas show frequent RAS-MAPK pathway mutations
TF Eleveld, DA Oldridge, V Bernard, J Koster, LC Daage, SJ Diskin, ...
Nature genetics 47 (8), 864-871, 2015
5352015
Neuroblastoma is composed of two super-enhancer-associated differentiation states
T Van Groningen, J Koster, LJ Valentijn, DA Zwijnenburg, N Akogul, ...
Nature genetics 49 (8), 1261-1266, 2017
4222017
LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression
JJ Molenaar, R Domingo-Fernández, ME Ebus, S Lindner, J Koster, ...
Nature genetics 44 (11), 1199-1206, 2012
4122012
TERT rearrangements are frequent in neuroblastoma and identify aggressive tumors
LJ Valentijn, J Koster, DA Zwijnenburg, NE Hasselt, P Van Sluis, ...
Nature genetics 47 (12), 1411-1414, 2015
3932015
Functional MYCN signature predicts outcome of neuroblastoma irrespective of MYCN amplification
LJ Valentijn, J Koster, F Haneveld, RA Aissa, P van Sluis, ...
Proceedings of the National Academy of Sciences 109 (47), 19190-19195, 2012
2442012
An organoid biobank for childhood kidney cancers that captures disease and tissue heterogeneity
C Calandrini, F Schutgens, R Oka, T Margaritis, T Candelli, L Mathijsen, ...
Nature communications 11 (1), 1310, 2020
2112020
Retinoblastoma and neuroblastoma predisposition and surveillance
J Kamihara, F Bourdeaut, WD Foulkes, JJ Molenaar, YP Mossé, ...
Clinical Cancer Research 23 (13), e98-e106, 2017
1982017
Inactivation of CDK2 is synthetically lethal to MYCN over-expressing cancer cells
JJ Molenaar, ME Ebus, D Geerts, J Koster, F Lamers, LJ Valentijn, ...
Proceedings of the National Academy of Sciences 106 (31), 12968-12973, 2009
1982009
Cyclin D1 and CDK4 activity contribute to the undifferentiated phenotype in neuroblastoma
JJ Molenaar, ME Ebus, J Koster, P Sluis, CJM van Noesel, R Versteeg, ...
Cancer research 68 (8), 2599-2609, 2008
1952008
Cancer surveillance in Gorlin syndrome and rhabdoid tumor predisposition syndrome
WD Foulkes, J Kamihara, DGR Evans, L Brugières, F Bourdeaut, ...
Clinical Cancer Research 23 (12), e62-e67, 2017
1702017
Resection margins in oral cancer surgery: room for improvement
RWH Smits, S Koljenović, JA Hardillo, I Ten Hove, CA Meeuwis, ...
Head & neck 38 (S1), E2197-E2203, 2016
1572016
Molecular characteristics and therapeutic vulnerabilities across paediatric solid tumours
DTW Jones, A Banito, TGP Grünewald, M Haber, N Jäger, M Kool, T Milde, ...
Nature Reviews Cancer 19 (8), 420-438, 2019
1492019
The pediatric precision oncology INFORM registry: clinical outcome and benefit for patients with very high-evidence targets
CM Van Tilburg, E Pfaff, KW Pajtler, KPS Langenberg, P Fiesel, BC Jones, ...
Cancer discovery 11 (11), 2764-2779, 2021
1262021
MYCN and ALKF1174L are sufficient to drive neuroblastoma development from neural crest progenitor cells
JH Schulte, S Lindner, A Bohrer, J Maurer, K De Preter, S Lefever, ...
Oncogene 32 (8), 1059-1065, 2013
1232013
The immune landscape of neuroblastoma: challenges and opportunities for novel therapeutic strategies in pediatric oncology
J Wienke, MP Dierselhuis, GAM Tytgat, A Künkele, S Nierkens, ...
European journal of cancer 144, 123-150, 2021
1142021
Recommendations for childhood cancer screening and surveillance in DNA repair disorders
MF Walsh, VY Chang, WK Kohlmann, HS Scott, C Cunniff, F Bourdeaut, ...
Clinical Cancer Research 23 (11), e23-e31, 2017
1142017
Knockdown of survivin (BIRC5) causes apoptosis in neuroblastoma via mitotic catastrophe
F Lamers, I Van Der Ploeg, L Schild, ME Ebus, J Koster, BR Hansen, ...
Endocrine Related Cancer 18 (6), 657, 2011
1072011
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