| Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia T Palomero, ML Sulis, M Cortina, PJ Real, K Barnes, M Ciofani, ... Nature medicine 13 (10), 1203-1210, 2007 | 1042 | 2007 |
| NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth T Palomero, WK Lim, DT Odom, ML Sulis, PJ Real, A Margolin, ... Proceedings of the National Academy of Sciences 103 (48), 18261-18266, 2006 | 1031 | 2006 |
| Recurrent mutations in epigenetic regulators, RHOA and FYN kinase in peripheral T cell lymphomas T Palomero, L Couronné, H Khiabanian, MY Kim, A Ambesi-Impiombato, ... Nature genetics 46 (2), 166-170, 2014 | 665 | 2014 |
| The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia BJ Thompson, S Buonamici, ML Sulis, T Palomero, T Vilimas, G Basso, ... Journal of Experimental Medicine 204 (8), 1825-1835, 2007 | 560 | 2007 |
| γ-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia PJ Real, V Tosello, T Palomero, M Castillo, E Hernando, E De Stanchina, ... Nature medicine 15 (1), 50-58, 2009 | 494 | 2009 |
| Whole exome sequencing to identify a novel gene (caveolin-1) associated with human pulmonary arterial hypertension ED Austin, L Ma, C LeDuc, EB Rosenzweig, A Borczuk, JA Phillips, ... Circulation: Cardiovascular Genetics, CIRCGENETICS. 111.961888, 2012 | 456 | 2012 |
| A NOTCH1-driven MYC enhancer promotes T cell development, transformation and acute lymphoblastic leukemia D Herranz, A Ambesi-Impiombato, T Palomero, SA Schnell, L Belver, ... Nature medicine 20 (10), 1130-1137, 2014 | 441 | 2014 |
| Genome-wide RNA-mediated interference screen identifies miR-19 targets in Notch-induced T-cell acute lymphoblastic leukaemia KJ Mavrakis, AL Wolfe, E Oricchio, T Palomero, K De Keersmaecker, ... Nature cell biology 12 (4), 372-379, 2010 | 425 | 2010 |
| Targeting the NF-κB signaling pathway in Notch1-induced T-cell leukemia T Vilimas, J Mascarenhas, T Palomero, M Mandal, S Buonamici, F Meng, ... Nature medicine 13 (1), 70-77, 2007 | 418 | 2007 |
| The mutational landscape of cutaneous T cell lymphoma and Sézary syndrome AC da Silva Almeida, F Abate, H Khiabanian, E Martinez-Escala, J Guitart, ... Nature genetics 47 (12), 1465-1470, 2015 | 395 | 2015 |
| Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL G Tzoneva, A Perez-Garcia, Z Carpenter, H Khiabanian, V Tosello, ... Nature medicine 19 (3), 368-371, 2013 | 379 | 2013 |
| PHF6 mutations in T-cell acute lymphoblastic leukemia P Van Vlierberghe, T Palomero, H Khiabanian, J Van der Meulen, ... Nature genetics 42 (4), 338-342, 2010 | 336 | 2010 |
| The role of the PTEN/AKT Pathway in NOTCH1-induced leukemia T Palomero, M Dominguez, AA Ferrando Cell cycle 7 (8), 965-970, 2008 | 284 | 2008 |
| Mutational landscape, clonal evolution patterns, and role of RAS mutations in relapsed acute lymphoblastic leukemia K Oshima, H Khiabanian, AC da Silva-Almeida, G Tzoneva, F Abate, ... Proceedings of the National Academy of Sciences, 201608420, 2016 | 197 | 2016 |
| Biallelic transcriptional activation of oncogenic transcription factors in T-cell acute lymphoblastic leukemia AA Ferrando, S Herblot, T Palomero, M Hansen, T Hoang, EA Fox, ... Blood 103 (5), 1909-1911, 2004 | 182 | 2004 |
| CUTLL1, a novel human T-cell lymphoma cell line with t (7; 9) rearrangement, aberrant NOTCH1 activation and high sensitivity to γ-secretase inhibitors T Palomero, KC Barnes, PJ Real, JLG Bender, ML Sulis, VV Murty, ... Leukemia 20 (7), 1279-1287, 2006 | 176 | 2006 |
| The TLX1 oncogene drives aneuploidy in T cell transformation K De Keersmaecker, PJ Real, G Della Gatta, T Palomero, ML Sulis, ... Nature medicine 16 (11), 1321-1327, 2010 | 172 | 2010 |
| The BCL2A1 gene as a pre–T cell receptor–induced regulator of thymocyte survival M Mandal, C Borowski, T Palomero, AA Ferrando, P Oberdoerffer, F Meng, ... Journal of Experimental Medicine 201 (4), 603-614, 2005 | 171 | 2005 |
| Reverse engineering of TLX oncogenic transcriptional networks identifies RUNX1 as tumor suppressor in T-ALL G Della Gatta, T Palomero, A Perez-Garcia, A Ambesi-Impiombato, ... Nature medicine 18 (3), 436-440, 2012 | 170 | 2012 |
| NOTCH1 extracellular juxtamembrane expansion mutations in T-ALL ML Sulis, O Williams, T Palomero, V Tosello, S Pallikuppam, PJ Real, ... Blood 112 (3), 733-740, 2008 | 168 | 2008 |
