Thiourea-catalyzed enantioselective cyanosilylation of ketones DE Fuerst, EN Jacobsen Journal of the American Chemical Society 127 (25), 8964-8965, 2005 | 411 | 2005 |
Chiral synthesis of LSD1 inhibitor GSK2879552 enabled by directed evolution of an imine reductase M Schober, C MacDermaid, AA Ollis, S Chang, D Khan, J Hosford, ... Nature Catalysis 2 (10), 909-915, 2019 | 160 | 2019 |
Synthesis of C (3) benzofuran-derived bisaryl quaternary centers: Approaches to diazonamide A DE Fuerst, BM Stoltz, JL Wood Organic letters 2 (22), 3521-3523, 2000 | 121 | 2000 |
A designed photoenzyme for enantioselective [2+ 2] cycloadditions JS Trimble, R Crawshaw, FJ Hardy, CW Levy, MJB Brown, DE Fuerst, ... Nature 611 (7937), 709-714, 2022 | 72 | 2022 |
Enzymatic amidation for industrial applications BM Dorr, DE Fuerst Current Opinion in Chemical Biology 43, 127-133, 2018 | 50 | 2018 |
Rhodium-catalyzed synthesis of a C (3) disubstituted oxindole: an approach to diazonamide A T Sawada, DE Fuerst, JL Wood Tetrahedron letters 44 (26), 4919-4921, 2003 | 49 | 2003 |
Biocatalysis in medicinal chemistry: Challenges to access and drivers for adoption NC Goodwin, JP Morrison, DE Fuerst, T Hadi ACS Medicinal Chemistry Letters 10 (10), 1363-1366, 2019 | 26 | 2019 |
Identification and implementation of biocatalytic transformations in route discovery: synthesis of chiral 1, 3-substituted cyclohexanone building blocks T Hadi, A Dı́az-Rodrı́guez, D Khan, JP Morrison, JM Kaplan, KT Gallagher, ... Organic Process Research & Development 22 (7), 871-879, 2018 | 21 | 2018 |
Development of an Enzymatic Process for the Production of (R)-2-Butyl-2-ethyloxirane GD Roiban, PW Sutton, R Splain, C Morgan, A Fosberry, K Honicker, ... Organic Process Research & Development 21 (9), 1302-1310, 2017 | 14 | 2017 |
Rolling circle amplification of synthetic DNA accelerates biocatalytic determination of enzyme activity relative to conventional methods T Hadi, N Nozzi, JO Melby, W Gao, DE Fuerst, E Kvam Scientific Reports 10 (1), 10279, 2020 | 11 | 2020 |
Carboxyesterase polypeptides for amide coupling R Voladri, D Entwistle, CM Micklitsch, V Mitchell, N Dellas, X Zhang, ... US Patent 11,015,180, 2021 | 3 | 2021 |
Directed evolution of enzymes driving innovation in API manufacturing at GSK J Latham, AA Ollis, C MacDermaid, K Honicker, D Fuerst, GD Roiban Applied Biocatalysis: The Chemist's Enzyme Toolbox, 1-25, 2020 | 3 | 2020 |
Synthesis of bis‐3‐alkyl‐5‐arylhydantoins and bis‐3‐alkyl‐5‐arylthiohydantoins separated by two and four carbon atoms OL Salerni, WK Van Tyle, DJ Mustra, KS Emerich, DE Fuerst, ... Journal of heterocyclic chemistry 36 (5), 1179-1182, 1999 | 2 | 1999 |
Carboxyesterase biocatalysts KK Brown, BM Dorr, DE Fuerst, KJ Honicker, LS Jordan, JP Morrison, ... US Patent 11,535,833, 2022 | 1 | 2022 |
Modification of saponins M Brown, E Chapman, A Collis, D Fuerst, J Hosford, C Macdermaid, ... US Patent App. 18/039,514, 2024 | | 2024 |
Carboxyesterase biocatalysts KK Brown, BM Dorr, DE Fuerst, KJ Honicker, LS Jordan, JP Morrison, ... US Patent App. 18/046,295, 2023 | | 2023 |
A Designed Photoenzyme Promotes Enantioselective [2+ 2]-Cycloadditions via Triplet Energy Transfer A Green, J Trimble, R Crawshaw, F Hardy, C Levy, M Brown, D Fuerst, ... | | 2022 |
Biocatalytic Resolutions P Clayman, GD Roiban, D Fuerst Elsevier, 2022 | | 2022 |
Carboxyesterase polypeptides for amide coupling R Voladri, D Entwistle, CM Micklitsch, V Mitchell, N Dellas, X Zhang, ... US Patent App. 17/236,928, 2021 | | 2021 |
7.5 Preparation of Methyl (S)-3-Oxocyclohexanecarboxylate Using an Enoate Reductase A Diaz-Rodriguez, T Hadi, R Snajdrova, D Fuerst, GD Roiban Applied Biocatalysis, 277, 2021 | | 2021 |