| The folding of an enzyme: I. Theory of protein engineering analysis of stability and pathway of protein folding AR Fersht, A Matouschek, L Serrano Journal of molecular biology 224 (3), 771-782, 1992 | 1073 | 1992 |
| Mapping the transition state and pathway of protein folding by protein engineering A Matouschek, JT Kellis Jr, L Serrano, AR Fersht Nature 340 (6229), 122-126, 1989 | 901 | 1989 |
| Aggregated and monomeric α-synuclein bind to the S6′ proteasomal protein and inhibit proteasomal function H Snyder, K Mensah, C Theisler, J Lee, A Matouschek, B Wolozin Journal of Biological Chemistry 278 (14), 11753-11759, 2003 | 594 | 2003 |
| Transient folding intermediates characterized by protein engineering A Matouschek, JT Kellis Jr, L Serrano, M Bycroft, AR Fersht Nature 346 (6283), 440-445, 1990 | 571 | 1990 |
| An unstructured initiation site is required for efficient proteasome-mediated degradation S Prakash, L Tian, KS Ratliff, RE Lehotzky, A Matouschek Nature structural & molecular biology 11 (9), 830-837, 2004 | 552 | 2004 |
| The folding of an enzyme: II. Substructure of barnase and the contribution of different interactions to protein stability L Serrano, JT Kellis Jr, P Cann, A Matouschek, AR Fersht Journal of molecular biology 224 (3), 783-804, 1992 | 516 | 1992 |
| ATP-dependent proteases degrade their substrates by processively unraveling them from the degradation signal C Lee, MP Schwartz, S Prakash, M Iwakura, A Matouschek Molecular cell 7 (3), 627-637, 2001 | 508 | 2001 |
| Targeting proteins for degradation EK Schrader, KG Harstad, A Matouschek Nature chemical biology 5 (11), 815-822, 2009 | 382 | 2009 |
| Inefficient degradation of truncated polyglutamine proteins by the proteasome CI Holmberg, KE Staniszewski, KN Mensah, A Matouschek, RI Morimoto The EMBO journal 23 (21), 4307-4318, 2004 | 381 | 2004 |
| Regulated protein turnover: snapshots of the proteasome in action S Bhattacharyya, H Yu, C Mim, A Matouschek Nature reviews Molecular cell biology 15 (2), 122-133, 2014 | 327 | 2014 |
| The folding of an enzyme: III. Structure of the transition state for unfolding of barnase analysed by a protein engineering procedure L Serrano, A Matouschek, AR Fersht Journal of molecular biology 224 (3), 805-818, 1992 | 327 | 1992 |
| Detection and characterization of a folding intermediate in barnase by NMR M Bycroft, A Matouschek, JT Kellis Jr, L Serrano, AR Fersht Nature 346 (6283), 488-490, 1990 | 268 | 1990 |
| The folding of an enzyme: IV. Structure of an intermediate in the refolding of barnase analysed by a protein engineering procedure A Matouschek, L Serrano, AR Fersht Journal of molecular biology 224 (3), 819-835, 1992 | 260 | 1992 |
| Cyclophilin catalyzes protein folding in yeast mitochondria. A Matouschek, S Rospert, K Schmid, BS Glick, G Schatz Proceedings of the National Academy of Sciences 92 (14), 6319-6323, 1995 | 250 | 1995 |
| Intrinsically disordered segments affect protein half-life in the cell and during evolution R van der Lee, B Lang, K Kruse, J Gsponer, NS de Groot, MA Huynen, ... Cell reports 8 (6), 1832-1844, 2014 | 245 | 2014 |
| Application of physical organic chemistry to engineered mutants of proteins: Hammond postulate behavior in the transition state of protein folding. A Matouschek, AR Fersht Proceedings of the National Academy of Sciences 90 (16), 7814-7818, 1993 | 245 | 1993 |
| Protein unfolding—an important process in vivo? A Matouschek Current opinion in structural biology 13 (1), 98-109, 2003 | 217 | 2003 |
| Protein unfolding by mitochondria A Matouschek, N Pfanner, W Voos EMBO reports, 2000 | 216 | 2000 |
| Lack of a robust unfoldase activity confers a unique level of substrate specificity to the universal AAA protease FtsH C Herman, S Prakash, CZ Lu, A Matouschek, CA Gross Molecular cell 11 (3), 659-669, 2003 | 210 | 2003 |
| Defining the geometry of the two-component proteasome degron T Inobe, S Fishbain, S Prakash, A Matouschek Nature chemical biology 7 (3), 161-167, 2011 | 189 | 2011 |
Alan FershtEmeritus Group Leader, MRC Laboratory of Molecular Biology, University of CambridgeVerified email at cam.ac.uk
