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Charles S. Shanahan, Ph.D.
Charles S. Shanahan, Ph.D.
Director of Research, Medicines for All Institute
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Divergent stereocontrol of acid catalyzed intramolecular Aldol reactions of 2, 3, 7-triketoesters: synthesis of highly functionalized cyclopentanones
P Truong, CS Shanahan, MP Doyle
Organic letters 14 (14), 3608-3611, 2012
622012
The Pauson–Khand reaction as a new entry to the synthesis of bridged bicyclic heterocycles: application to the enantioselective total synthesis of (−)-alstonerine
KA Miller, CS Shanahan, SF Martin
Tetrahedron 64 (29), 6884-6900, 2008
472008
Enantioselective Formal Total Syntheses of Didehydrostemofoline and Isodidehydrostemofoline via a Novel Catalytic Dipolar Cycloaddition Cascade
C Fang, CS Shanahan, DH Paull, SF Martin
Angewandte Chemie (International ed. in English) 51 (42), 10596, 2012
402012
Diazoacetoacetate enones for the synthesis of diverse natural product-like scaffolds
CS Shanahan, P Truong, SM Mason, JS Leszczynski, MP Doyle
Organic letters 15 (14), 3642-3645, 2013
312013
Asymmetric formal total synthesis of the stemofoline alkaloids: the evolution, development, and application of a catalytic dipolar cycloaddition cascade
CS Shanahan, C Fang, DH Paull, SF Martin
Tetrahedron 69 (36), 7592-7607, 2013
292013
Templated Carbene Metathesis Reactions from the Modular Assembly of Enol‐diazo Compounds and Propargyl Acetates
Y Qian, CS Shanahan, MP Doyle
European Journal of Organic Chemistry 2013 (27), 6032-6037, 2013
282013
Vanillin and o-vanillin oligomers as models for dendrimer disassembly
RM Kevwitch, CS Shanahan, DV McGrath
New Journal of Chemistry 36 (2), 492-505, 2012
272012
Convergent Synthesis of Geometrically Disassembling Dendrimers using Cu (I)-Catalyzed C− O Bond Formation
NW Polaske, ML Szalai, CS Shanahan, DV McGrath
Organic Letters 12 (21), 4944-4947, 2010
252010
Toward a total synthesis of the stemofoline alkaloids: advancement of a 1, 3-dipolar cycloaddition strategy
CS Shanahan, NO Fuller, B Ludolph, SF Martin
Tetrahedron letters 52 (32), 4076-4079, 2011
222011
Improved iterative synthesis of linearly disassembling dendrons
A Ortiz, CS Shanahan, DT Sisk, SC Perera, P Rao, DV McGrath
The Journal of Organic Chemistry 75 (18), 6154-6162, 2010
192010
A survey of enoldiazo nucleophilicity in selective C–C bond forming reactions for the synthesis of natural product-like frameworks
Y Liu, Y Liu, CS Shanahan, X Xu, MP Doyle
Organic & Biomolecular Chemistry 12 (28), 5227-5234, 2014
142014
Total synthesis of (−)-dihydroprotolichesterenic acid via diastereoselective conjugate addition to a chiral fumarate
JC Hethcox, CS Shanahan, SF Martin
Tetrahedron letters 54 (16), 2074-2076, 2013
112013
A general method for fouling injectors in gasoline direct injection vehicles and the effects of deposits on vehicle performance
CS Shanahan, SS Smith, BD Sears
SAE International Journal of Fuels and Lubricants 10 (3), 778-788, 2017
72017
Synthesis and Characterization of BHT-Derived tert-Butyl Dendrons
CS Shanahan, DV McGrath
The Journal of Organic Chemistry 70 (3), 1054-1056, 2005
72005
Efforts to develop a cost-effective and scalable synthetic process for nirmatrelvir
CS Shanahan, AL Kadam, B Chiranjeevi, AA Nunes, A Jayaraman, ...
American Chemical Society (ACS), 2022
62022
Diastereoselective addition of monoorganocuprates to a chiral fumarate: reaction development and synthesis of (−)-dihydroprotolichesterinic acid
JC Hethcox, CS Shanahan, SF Martin
Tetrahedron 71 (37), 6361-6368, 2015
52015
Thermally Induced Intramolecular Benzannulation of Diazoacetoacetate Enones Tethered with Unactivated Alkynes: Synthesis of Substituted 6H-Benzo [c] chromenes
Y Chen, D Wu, J Zhou, Y Wang, J Huang, X Xu
Synthesis 51 (22), 4165-4169, 2019
42019
Application of Chiral Transfer Reagents to Improve Stereoselectivity and Yields in the Synthesis of the Antituberculosis Drug Bedaquiline
JMS Robey, S Maity, SL Aleshire, A Ghosh, AK Yadaw, S Roy, SJ Mear, ...
Organic Process Research & Development 27 (11), 2146-2159, 2023
22023
Selective 1, 4-Addition of Organolithiums to Maleate Monoesters with Application for a Short Efficient Route to Azaindanones
Z Liu, AM Hyde, A Klapars, JYL Chung, Y Lam, N Yasuda
Synlett 32 (02), 192-196, 2021
22021
LEWIS ACID CATALYZED DIASTEREOSELECTIVE 1, 3-DIPOLAR CYCLOADDITION BETWEEN DIAZOACETOACETATE ENONES AND AZOMETHINE YLIDES
PM Truong, MD Mandler, CS Shanahan
Heterocycles: an international journal for reviews and communications in …, 2014
22014
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