Quantifying drug combination synergy along potency and efficacy axes CT Meyer, DJ Wooten, BB Paudel, J Bauer, KN Hardeman, D Westover, ... Cell systems 8 (2), 97-108. e16, 2019 | 150 | 2019 |
Charting the fragmented landscape of drug synergy CT Meyer, DJ Wooten, CF Lopez, V Quaranta Trends in pharmacological sciences 41 (4), 266-280, 2020 | 62 | 2020 |
MuSyC is a consensus framework that unifies multi-drug synergy metrics for combinatorial drug discovery DJ Wooten, CT Meyer, ALR Lubbock, V Quaranta, CF Lopez Nature communications 12 (1), 4607, 2021 | 60* | 2021 |
Dependence on glycolysis sensitizes BRAF-mutated melanomas for increased response to targeted BRAF inhibition KN Hardeman, C Peng, BB Paudel, CT Meyer, T Luong, DR Tyson, ... Scientific reports 7 (1), 42604, 2017 | 56 | 2017 |
Differential cell susceptibilities to KrasG12D in the setting of obstructive chronic pancreatitis C Shi, FC Pan, JN Kim, MK Washington, C Padmanabhan, CT Meyer, ... Cellular and molecular gastroenterology and hepatology 8 (4), 579-594, 2019 | 21 | 2019 |
Translatome proteomics identifies autophagy as a resistance mechanism to on-target FLT3 inhibitors in acute myeloid leukemia SE Koschade, K Klann, S Shaid, B Vick, JA Stratmann, M Thölken, ... Leukemia 36 (10), 2396-2407, 2022 | 15 | 2022 |
Activation of STAT3 through combined SRC and EGFR signaling drives resistance to a mitotic kinesin inhibitor in glioblastoma RS Kenchappa, A Dovas, MG Argenziano, CT Meyer, LE Stopfer, ... Cell reports 39 (12), 2022 | 10 | 2022 |
Machine learning establishes single-cell calcium dynamics as an early indicator of antibiotic response CT Meyer, MP Jewell, EJ Miller, JM Kralj Microorganisms 9 (5), 1000, 2021 | 8 | 2021 |
A high-throughput and low-waste viability assay for microbes CT Meyer, GK Lynch, DF Stamo, EJ Miller, A Chatterjee, JM Kralj Nature Microbiology 8 (12), 2304-2314, 2023 | 3 | 2023 |
A global sensitivity analysis of a mechanistic model of neoadjuvant chemotherapy for triple negative breast cancer constrained by in vitro and in vivo imaging data G Lorenzo, AM Jarrett, CT Meyer, JC DiCarlo, J Virostko, V Quaranta, ... Engineering with Computers, 1-31, 2023 | 2 | 2023 |
Identifying mechanisms driving the early response of triple negative breast cancer patients to neoadjuvant chemotherapy using a mechanistic model integrating in vitro and in … G Lorenzo, AM Jarrett, CT Meyer, V Quaranta, DR Tyson, TE Yankeelov arXiv preprint arXiv:2212.04270, 2022 | 2 | 2022 |
MuSyC dosing of adjuvanted cancer vaccines optimizes antitumor responses D Taylor, CT Meyer, D Graves, R Sen, J Fu, E Tran, B Mirza, G Rodriguez, ... Frontiers in immunology 13, 936129, 2022 | 2 | 2022 |
Abstract PS13-44: Identifying relevant parameters that characterize the early response to NAT in breast cancer patients using a novel personalized mechanistic model integrating … G Lorenzo, AM Jarrett, CT Meyer, DR Tyson, V Quaranta, TE Yankeelov Cancer Research 81 (4_Supplement), PS13-44-PS13-44, 2021 | 1 | 2021 |
MT-125 Inhibits Non-Muscle Myosin IIA and IIB, Synergizes with Oncogenic Kinase Inhibitors, and Prolongs Survival in Glioblastoma R Kenchappa, L Radnai, EJ Young, N Zarco, L Lin, A Dovas, CT Meyer, ... bioRxiv, 2024.04. 27.591399, 2024 | | 2024 |
Bacterial efflux pump modulators prevent bacterial growth in macrophages and under broth conditions that mimic the host environment SC Allgood, CC Su, AL Crooks, CT Meyer, B Zhou, MD Betterton, ... Mbio 14 (6), e02492-23, 2023 | | 2023 |
A geometry-based approach to make viable-cell counting easy and cheap JM Kralj, CT Meyer NATURE MICROBIOLOGY 8 (12), 2242-2243, 2023 | | 2023 |
Cell-autonomous diversification in bacteria arises from calcium dynamics self-organizing at a critical point CT Meyer, JM Kralj Science Advances 9 (31), eadg3028, 2023 | | 2023 |
In silico analysis of a novel mathematical model integrating in vitro and in vivo imaging data reveals driving mechanisms of breast cancer response to NAT for personalized … G Lorenzo, AM Jarrett, CT Meyer, DR Tyson, V Quaranta, TE Yankeelov CANCER RESEARCH 82 (4), 2022 | | 2022 |
Methods for evaluating therapeutic benefit of combination therapies CT Meyer, V Quaranta, LA Harris, BB Paudel, DJ Wooten, L Audoly US Patent App. 17/180,280, 2021 | | 2021 |
Aminoglycosides induce a bacterial senescent state that increases antibiotic tolerance in treatment-naïve cells CT Meyer, GN Bruni, B Dodd, JM Kralj bioRxiv, 2021.10. 04.463054, 2021 | | 2021 |