Structural basis for mismatch surveillance by CRISPR–Cas9 JPK Bravo, MS Liu, GN Hibshman, TL Dangerfield, K Jung, RS McCool, ... Nature 603 (7900), 343-347, 2022 | 152 | 2022 |
Remdesivir is a delayed translocation inhibitor of SARS-CoV-2 replication JPK Bravo, TL Dangerfield, DW Taylor, KA Johnson Molecular cell 81 (7), 1548-1552. e4, 2021 | 113 | 2021 |
Liquid–liquid phase separation underpins the formation of replication factories in rotaviruses F Geiger, J Acker, G Papa, X Wang, WE Arter, KL Saar, NA Erkamp, R Qi, ... The EMBO Journal 40 (21), e107711, 2021 | 77* | 2021 |
SCOPE enables type III CRISPR-Cas diagnostics using flexible targeting and stringent CARF ribonuclease activation JA Steens, Y Zhu, DW Taylor, JPK Bravo, SHP Prinsen, CD Schoen, ... Nature communications 12 (1), 5033, 2021 | 67* | 2021 |
Structure of a type IV CRISPR-Cas ribonucleoprotein complex Y Zhou, JPK Bravo, HN Taylor, JA Steens, RN Jackson, RHJ Staals, ... Iscience 24 (3), 2021 | 32* | 2021 |
Stability of local secondary structure determines selectivity of viral RNA chaperones JPK Bravo, A Borodavka, A Barth, AN Calabrese, P Mojzes, JJB Cockburn, ... Nucleic acids research 46 (15), 7924-7937, 2018 | 32 | 2018 |
Structural basis for assembly of non-canonical small subunits into type IC Cascade RE O’Brien, IC Santos, D Wrapp, JPK Bravo, EA Schwartz, JS Brodbelt, ... Nature communications 11 (1), 5931, 2020 | 31 | 2020 |
Structural basis of rotavirus RNA chaperone displacement and RNA annealing JPK Bravo, K Bartnik, L Venditti, J Acker, EH Gail, A Colyer, C Davidovich, ... Proceedings of the National Academy of Sciences 118 (41), e2100198118, 2021 | 27 | 2021 |
Structural rearrangements allow nucleic acid discrimination by type ID Cascade EA Schwartz, TM McBride, JPK Bravo, D Wrapp, PC Fineran, ... Nature communications 13 (1), 2829, 2022 | 25 | 2022 |
RNA targeting unleashes indiscriminate nuclease activity of CRISPR–Cas12a2 JPK Bravo, T Hallmark, B Naegle, CL Beisel, RN Jackson, DW Taylor Nature 613 (7944), 582-587, 2023 | 24* | 2023 |
A single 2′-O-methylation of ribosomal RNA gates assembly of a functional ribosome JN Yelland, JPK Bravo, JJ Black, DW Taylor, AW Johnson Nature Structural & Molecular Biology 30 (1), 91-98, 2023 | 18 | 2023 |
Structural basis for broad anti-phage immunity by DISARM JPK Bravo, C Aparicio-Maldonado, FL Nobrega, SJJ Brouns, DW Taylor Nature Communications 13 (1), 2987, 2022 | 18 | 2022 |
RNA targeting and cleavage by the type III-Dv CRISPR effector complex EA Schwartz, JPK Bravo, M Ahsan, LA Macias, CL McCafferty, ... Nature Communications 15 (1), 3324, 2024 | 12* | 2024 |
Structural snapshots of R-loop formation by a type IC CRISPR Cascade RE O’Brien, JPK Bravo, D Ramos, GN Hibshman, JT Wright, DW Taylor Molecular cell 83 (5), 746-758. e5, 2023 | 7* | 2023 |
Constructing next-generation CRISPR–Cas tools from structural blueprints JPK Bravo, GN Hibshman, DW Taylor Current Opinion in Biotechnology 78, 102839, 2022 | 6 | 2022 |
Type III-B CRISPR-Cas cascade of proteolytic cleavages JA Steens, JPK Bravo, CRP Salazar, C Yildiz, AM Amieiro, S Köstlbacher, ... Science 383 (6682), 512-519, 2024 | 5 | 2024 |
Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9 GN Hibshman, JPK Bravo, MM Hooper, TL Dangerfield, H Zhang, ... Nature Communications 15 (1), 3663, 2024 | 3 | 2024 |
Plasmid targeting and destruction by the DdmDE bacterial defence system JPK Bravo, DA Ramos, RF Ocampo, C Ingram, DW Taylor Nature, 1-2, 2024 | | 2024 |
DNA targeting by compact Cas9d and its resurrected ancestor R Fregoso Ocampo, JPK Bravo, TL Dangerfield, I Noceda, S Jirde, ... bioRxiv, 2024.04. 08.588528, 2024 | | 2024 |