Æȷοì
Zibo Chen
Zibo Chen
Westlake University
westlake.edu.cnÀÇ À̸ÞÀÏ È®ÀÎµÊ - ȨÆäÀÌÁö
Á¦¸ñ
Àοë
Àοë
¿¬µµ
A cargo-sorting DNA robot
AJ Thubagere, W Li, RF Johnson, Z Chen, S Doroudi, YL Lee, G Izatt, ...
Science 357 (6356), eaan6558, 2017
4812017
De novo design of protein homo-oligomers with modular hydrogen-bond network–mediated specificity
SE Boyken, Z Chen, B Groves, RA Langan, G Oberdorfer, A Ford, ...
Science 352 (6286), 680-687, 2016
3522016
De novo design of bioactive protein switches
RA Langan, SE Boyken, AH Ng, JA Samson, G Dods, AM Westbrook, ...
Nature 572 (7768), 205-210, 2019
2492019
Programmable design of orthogonal protein heterodimers
Z Chen, SE Boyken, M Jia, F Busch, D Flores-Solis, MJ Bick, P Lu, ...
Nature 565 (7737), 106-111, 2019
1782019
De novo design of protein logic gates
Z Chen, RD Kibler, A Hunt, F Busch, J Pearl, M Jia, ZL VanAernum, ...
Science 368 (6486), 78-84, 2020
1752020
Accurate computational design of multipass transmembrane proteins
P Lu, D Min, F DiMaio, KY Wei, MD Vahey, SE Boyken, Z Chen, JA Fallas, ...
Science 359 (6379), 1042-1046, 2018
1692018
De novo design of tunable, pH-driven conformational changes
SE Boyken, MA Benhaim, F Busch, M Jia, MJ Bick, H Choi, JC Klima, ...
Science 364 (6441), 658-664, 2019
1402019
Rapid online buffer exchange for screening of proteins, protein complexes and cell lysates by native mass spectrometry
ZL VanAernum, F Busch, BJ Jones, M Jia, Z Chen, SE Boyken, ...
Nature protocols 15 (3), 1132-1157, 2020
1132020
S. 1 Wittman, N. Srinivas and D. Woods
AJ Thubagere, W Li, RF Johnson, Z Chen, S Doroudi, YL Lee, G Izatt
Science 357, 6356, 2017
612017
Programmable protein circuit design
Z Chen, MB Elowitz
Cell 184 (9), 2284-2301, 2021
602021
Self-Assembling 2D Arrays with de Novo Protein Building Blocks
Z Chen, MC Johnson, J Chen, MJ Bick, SE Boyken, B Lin, JJ De Yoreo, ...
Journal of the American Chemical Society 141 (22), 8891-8895, 2019
382019
Functional expression and characterization of the envelope glycoprotein E1E2 heterodimer of hepatitis C virus
L Cao, B Yu, D Kong, Q Cong, T Yu, Z Chen, Z Hu, H Chang, J Zhong, ...
PLoS pathogens 15 (5), e1007759, 2019
312019
Interpreting neural networks for biological sequences by learning stochastic masks
J Linder, A La Fleur, Z Chen, A Ljubetič, D Baker, S Kannan, G Seelig
Nature machine intelligence 4 (1), 41-54, 2022
182022
Modulating mechanical stability of heterodimerization between engineered orthogonal helical domains
M Yu, Z Zhao, Z Chen, S Le, J Yan
Nature communications 11 (1), 4476, 2020
132020
A game-theoretic model of interactions between Hibiscus latent Singapore virus and Tobacco mosaic virus
Z Chen, JY Tan, Y Wen, S Niu, SM Wong
PLoS One 7 (5), e37007, 2012
122012
A synthetic protein-level neural network in mammalian cells
Z Chen, JM Linton, R Zhu, MB Elowitz
bioRxiv, 2022.07. 10.499405, 2022
102022
Rapid online buffer exchange: A method for screening of proteins, protein complexes, and cell lysates by native mass spectrometry
Z VanAernum, F Busch, BJ Jones, M Jia, Z Chen, SE Boyken, ...
ChemRxiv. org, 2019
62019
Competitive Displacement of De Novo Designed HeteroDimers Can Reversibly Control Protein–Protein Interactions and Implement Feedback in Synthetic Circuits
TH Nguyen, G Dods, M Gómez-Schiavon, M Wu, Z Chen, R Kibler, ...
GEN Biotechnology 1 (1), 91-100, 2022
32022
Protein circuit design using de novo proteins
Z Chen
Trends in Biotechnology, 2023
12023
De novo design of phosphorylation inducible protein switches (phospho-switches)
N Woodall, S Boyken, MJ Lajoie, C Zibo, RA Langan, D Baker
US Patent App. 17/618,117, 2022
12022
ÇöÀç ½Ã½ºÅÛÀÌ ÀÛµ¿µÇÁö ¾Ê½À´Ï´Ù. ³ªÁß¿¡ ´Ù½Ã ½ÃµµÇØ ÁÖ¼¼¿ä.
ÇмúÀÚ·á 1–20