Whole‐genome sequencing identifies EN1 as a determinant of bone density and fracture HF Zheng, V Forgetta, YH Hsu, K Estrada, A Rosello‐Diez, PJ Leo, ... Nature 526 (7571), 112-117, 2015 | 536 | 2015 |
Defining the consequences of genetic variation on a proteome-wide scale JM Chick, SC Munger, P Simecek, EL Huttlin, K Choi, DM Gatti, ... Nature 534 (7608), 500-505, 2016 | 347 | 2016 |
PRDM9 drives evolutionary erosion of hotspots in Mus musculus through haplotype-specific initiation of meiotic recombination CL Baker, S Kajita, M Walker, RL Saxl, N Raghupathy, K Choi, PM Petkov, ... PLoS genetics 11 (1), e1004916, 2015 | 155 | 2015 |
Phenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment JP Kemp, C Medina-Gomez, K Estrada, B St Pourcain, DHM Heppe, ... PLoS genetics 10 (6), e1004423, 2014 | 154 | 2014 |
RNA-Seq alignment to individualized genomes improves transcript abundance estimates in multiparent populations SC Munger, N Raghupathy, K Choi, AK Simons, DM Gatti, DA Hinerfeld, ... Genetics 198 (1), 59-73, 2014 | 89 | 2014 |
Affinity-seq detects genome-wide PRDM9 binding sites and reveals the impact of prior chromatin modifications on mammalian recombination hotspot usage M Walker, T Billings, CL Baker, N Powers, H Tian, RL Saxl, K Choi, ... Epigenetics & chromatin 8, 1-13, 2015 | 86 | 2015 |
Hierarchical analysis of RNA-seq reads improves the accuracy of allele-specific expression N Raghupathy, K Choi, MJ Vincent, GL Beane, KS Sheppard, SC Munger, ... Bioinformatics 34 (13), 2177-2184, 2018 | 78 | 2018 |
Bayesian model selection reveals biological origins of zero inflation in single-cell transcriptomics K Choi, Y Chen, DA Skelly, GA Churchill Genome biology 21, 1-16, 2020 | 60 | 2020 |
Natural genetic variation determines microglia heterogeneity in wild-derived mouse models of Alzheimer’s disease HS Yang, KD Onos, K Choi, KJ Keezer, DA Skelly, GW Carter, GR Howell Cell Reports 34 (6), 2021 | 58 | 2021 |
Mapping the effects of genetic variation on chromatin state and gene expression reveals loci that control ground state pluripotency DA Skelly, A Czechanski, C Byers, S Aydin, C Spruce, C Olivier, K Choi, ... Cell Stem Cell 27 (3), 459-469. e8, 2020 | 28 | 2020 |
A Bayesian mixture model for the analysis of allelic expression in single cells K Choi, N Raghupathy, GA Churchill Nature communications 10 (1), 5188, 2019 | 28 | 2019 |
Comparison of phylogenetic trees through alignment of embedded evolutionary distances K Choi, SM Gomez BMC bioinformatics 10, 1-15, 2009 | 27 | 2009 |
Tissue-Specific Trans Regulation of the Mouse Epigenome CL Baker, M Walker, S Arat, G Ananda, P Petkova, NR Powers, H Tian, ... Genetics 211 (3), 831-845, 2019 | 18 | 2019 |
Prediction of protein‐protein interaction networks SM Gomez, K Choi, Y Wu Current Protocols in Bioinformatics 22 (1), 8.2. 1-8.2. 14, 2008 | 13 | 2008 |
Airpart: interpretable statistical models for analyzing allelic imbalance in single-cell datasets W Mu, H Sarkar, A Srivastava, K Choi, R Patro, MI Love Bioinformatics 38 (10), 2773-2780, 2022 | 9 | 2022 |
Genotype-free individual genome reconstruction of Multiparental Population Models by RNA sequencing data K Choi, H He, DM Gatti, VM Philip, N Raghupathy, SC Munger, ... bioRxiv, 2020.10. 11.335323, 2020 | 8 | 2020 |
Genetic variation influences pluripotent ground state stability in mouse embryonic stem cells through a hierarchy of molecular phenotypes DA Skelly, A Czechanski, C Byers, S Aydin, C Spruce, C Olivier, K Choi, ... BioRxiv, 552059, 2019 | 7 | 2019 |
The effects of sex and diet on physiology and liver gene expression in Diversity Outbred mice DM Gatti, P Simecek, L Somes, CT Jeffrey, MJ Vincent, K Choi, X Chen, ... bioRxiv, 098657, 2017 | 7 | 2017 |
SEESAW: detecting isoform-level allelic imbalance accounting for inferential uncertainty EY Wu, NP Singh, K Choi, M Zakeri, M Vincent, GA Churchill, ... Genome biology 24 (1), 165, 2023 | 3 | 2023 |
A large-scale whole genome sequence-based analysis discovered novel genetic variants influencing bone mineral density: Results from the GEFOS and UK10K Consortia HF Zheng, V Forgetta, YH Hsu, K Estrada, P Leo, J Tobias, C Kooperberg, ... 29. Annual Meeting of the American-Society-for-Bone-and-Mineral-Research 29, 2014 | 1 | 2014 |