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Floriano Paes Silva Junior
Floriano Paes Silva Junior
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Key topics in molecular docking for drug design
PHM Torres, ACR Sodero, P Jofily, FP Silva-Jr
International journal of molecular sciences 20 (18), 4574, 2019
3862019
Synthesis, Biological Activity, and Molecular Modeling Studies of 1H-1,2,3-Triazole Derivatives of Carbohydrates as ¥á-Glucosidases Inhibitors
SB Ferreira, ACR Sodero, MFC Cardoso, ES Lima, CR Kaiser, FP Silva Jr, ...
Journal of medicinal chemistry 53 (6), 2364-2375, 2010
3062010
Evaluation of the energy expenditure in competitive swimming strokes
TM Barbosa, R Fernandes, KL Keskinen, P Colaço, C Cardoso, J Silva, ...
International journal of sports medicine, 894-899, 2006
2042006
In silico Strategies to Support Fragment-to-Lead Optimization in Drug Discovery
LR de Souza Neto, JT Moreira-Filho, BJ Neves, RLBR Maidana, ...
Frontiers in chemistry 8, 93, 2020
1642020
The diverse mechanisms and anticancer potential of naphthoquinones
CE Pereyra, RF Dantas, SB Ferreira, LP Gomes, FP Silva-Jr
Cancer Cell International 19, 1-20, 2019
1572019
Filtering promiscuous compounds in early drug discovery: is it a good idea?
MR Senger, CAM Fraga, RF Dantas, FP Silva Jr
Drug Discovery Today 21 (6), 868-872, 2016
942016
Treatment by testicular sperm extraction and intracytoplasmic sperm injection of 65 azoospermic patients with non‐mosaic Klinefelter syndrome with birth of 17 healthy children
C Madureira, M Cunha, M Sousa, AP Neto, MJ Pinho, P Viana, ...
Andrology 2 (4), 623-631, 2014
882014
1-Phenyl-1H-and 2-phenyl-2H-1, 2, 3-triazol derivatives: Design, synthesis and inhibitory effect on alpha-glycosidases
D Gonzaga, MR Senger, FC Da Silva, VF Ferreira, FP Silva-Jr
European Journal of Medicinal Chemistry 74, 461-476, 2014
702014
Exploring the DNA binding/cleavage, cellular accumulation and topoisomerase inhibition of 2-hydroxy-3-(aminomethyl)-1, 4-naphthoquinone Mannich bases and their platinum (II ¡¦
AP Neves, MXG Pereira, EJ Peterson, R Kipping, MD Vargas, FP Silva-Jr, ...
Journal of inorganic biochemistry 119, 54-64, 2013
672013
Isolation and expression of a hypotensive and anti-platelet acidic phospholipase A2 from Bothrops moojeni snake venom
LB Silveira, DP Marchi-Salvador, NA Santos-Filho, FP Silva Jr, S Marcussi, ...
Journal of pharmaceutical and biomedical analysis 73, 35-43, 2013
672013
Molecular characterization of an acidic phospholipase A2 from Bothrops pirajai snake venom: synthetic C-terminal peptide identifies its antiplatelet region
SS Teixeira, LB Silveira, FMN da Silva, DP Marchi-Salvador, FP Silva, ...
Archives of toxicology 85, 1219-1233, 2011
622011
Enzymatic and structural characterization of a basic phospholipase A2 from the sea anemone Condylactis gigantea
L Romero, S Marcussi, DP Marchi-Salvador, FP Silva Jr, AL Fuly, ...
Biochimie 92 (8), 1063-1071, 2010
622010
Trypanosomatidae peptidases: a target for drugs development
A Beatriz Vermelho, S Giovanni De Simone, C Masini d'Avila-Levy, ...
Current Enzyme Inhibition 3 (1), 19-48, 2007
612007
De novo design and bioactivity prediction of SARS-CoV-2 main protease inhibitors using recurrent neural network-based transfer learning
MVS Santana, FP Silva-Jr
BMC chemistry 15 (1), 8, 2021
552021
Schistosoma mansoni infection causes oxidative stress and alters receptor for advanced glycation endproduct (RAGE) and tau levels in multiple organs in mice
RB de Oliveira, MR Senger, LM Vasques, J Gasparotto, JPA dos Santos, ...
International journal for parasitology 43 (5), 371-379, 2013
552013
Thermostability improvement of Orpinomyces sp. xylanase by directed evolution
LM Trevizano, RZ Ventorim, ST de Rezende, FPS Junior, VM Guimarães
Journal of Molecular Catalysis B: Enzymatic 81, 12-18, 2012
532012
Biochemical and molecular modeling analysis of the ability of two p-aminobenzamidine-based sorbents to selectively purify serine proteases (fibrinogenases) from snake venoms
SG De-Simone, C Correa-Netto, OAC Antunes, RB De-Alencastro, ...
Journal of Chromatography B 822 (1-2), 1-9, 2005
532005
QSAR-Driven Discovery of Novel Chemical Scaffolds Active against Schistosoma mansoni
CC Melo-Filho, RF Dantas, RC Braga, BJ Neves, MR Senger, ...
Journal of chemical information and modeling 56 (7), 1357-1372, 2016
522016
Synthesis and evaluation of the cytotoxic activity of 1, 2-furanonaphthoquinones tethered to 1, 2, 3-1H-triazoles in myeloid and lymphoid leukemia cell lines
MFC Cardoso, PC Rodrigues, MEIM Oliveira, IL Gama, IMCB da Silva, ...
European Journal of Medicinal Chemistry 84, 708-717, 2014
512014
Kinetics Studies on the Inhibition Mechanism of Pancreatic ¥á‐Amylase by Glycoconjugated 1H‐1,2,3‐Triazoles: A New Class of Inhibitors with Hypoglycemiant ¡¦
MR Senger, LCA Gomes, SB Ferreira, CR Kaiser, VF Ferreira, FP Silva Jr
ChemBioChem 13 (11), 1584-1593, 2012
512012
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