| Proteome analysis and tissue microarray for profiling protein markers associated with lymph node metastasis in colorectal cancer H Pei, H Zhu, S Zeng, Y Li, H Yang, L Shen, J Chen, L Zeng, J Fan, X Li, ... Journal of proteome research 6 (7), 2495-2501, 2007 | 143 | 2007 |
| Application of PBPK modeling and simulation for regulatory decision making and its impact on US prescribing information: an update on the 2018‐2019 submissions to the US FDA's … X Zhang, Y Yang, M Grimstein, J Fan, JA Grillo, SM Huang, H Zhu, ... The Journal of Clinical Pharmacology 60, S160-S178, 2020 | 135 | 2020 |
| Physiologically based pharmacokinetic modeling of nanoparticles D Yuan, H He, Y Wu, J Fan, Y Cao Journal of pharmaceutical sciences 108 (1), 58-72, 2019 | 128 | 2019 |
| Low Buffer Capacity and Alternating Motility along the Human Gastrointestinal Tract: Implications for in Vivo Dissolution and Absorption of Ionizable Drugs B Hens, Y Tsume, M Bermejo, P Paixao, MJ Koenigsknecht, JR Baker, ... Molecular pharmaceutics 14 (12), 4281-4294, 2017 | 116 | 2017 |
| Interplay of transporters and enzymes in drug and metabolite processing KS Pang, HJ Maeng, J Fan Molecular Pharmaceutics 6 (6), 1734-1755, 2009 | 114 | 2009 |
| Up-regulation of transporters and enzymes by the vitamin D receptor ligands, 1α, 25-dihydroxyvitamin D3 and vitamin D analogs, in the Caco-2 cell monolayer J Fan, S Liu, Y Du, J Morrison, R Shipman, KS Pang Journal of pharmacology and experimental therapeutics 330 (2), 389-402, 2009 | 112 | 2009 |
| FDA approval summary: alpelisib plus fulvestrant for patients with HR-positive, HER2-negative, PIK3CA-mutated, advanced or metastatic breast cancer P Narayan, TM Prowell, JJ Gao, LL Fernandes, E Li, X Jiang, J Qiu, J Fan, ... Clinical Cancer Research 27 (7), 1842-1849, 2021 | 105 | 2021 |
| Vitamin D receptor activation down-regulates the small heterodimer partner and increases CYP7A1 to lower cholesterol ECY Chow, L Magomedova, HP Quach, R Patel, MR Durk, J Fan, ... Gastroenterology 146 (4), 1048-1059. e7, 2014 | 101 | 2014 |
| Connecting hydroxychloroquine in vitro antiviral activity to in vivo concentration for prediction of antiviral effect: a critical step in treating patients with coronavirus … J Fan, X Zhang, J Liu, Y Yang, N Zheng, Q Liu, K Bergman, K Reynolds, ... Clinical Infectious Diseases 71 (12), 3232-3236, 2020 | 89 | 2020 |
| Pharmacokinetics of tranexamic acid in patients undergoing cardiac surgery with use of cardiopulmonary bypass V Sharma, J Fan, A Jerath, KS Pang, B Bojko, J Pawliszyn, JM Karski, ... Anaesthesia 67 (11), 1242-1250, 2012 | 85 | 2012 |
| Saikosaponin-d attenuates the development of liver fibrosis by preventing hepatocyte injury J Fan, X Li, P Li, N Li, T Wang, H Shen, Y Siow, P Choy, Y Gong Biochemistry and cell biology 85 (2), 189-195, 2007 | 75 | 2007 |
| Bone morphogenetic protein 4 mediates bile duct ligation induced liver fibrosis through activation of Smad1 and ERK1/2 in rat hepatic stellate cells J Fan, H Shen, Y Sun, P Li, F Burczynski, M Namaka, Y Gong Journal of cellular physiology 207 (2), 499-505, 2006 | 72 | 2006 |
| PBPK modeling of intestinal and liver enzymes and transporters in drug absorption and sequential metabolism J Fan, S Chen, E CY Chow, K Sandy Pang Current drug metabolism 11 (9), 743-761, 2010 | 70 | 2010 |
| FDA approval summary: selumetinib for plexiform neurofibroma D Casey, S Demko, A Sinha, PS Mishra-Kalyani, Y Shen, S Khasar, ... Clinical Cancer Research 27 (15), 4142-4146, 2021 | 55 | 2021 |
| Evaluation and optimized selection of supersaturating drug delivery systems of posaconazole (BCS class 2b) in the gastrointestinal simulator (GIS): An in vitro-in silico-in … B Hens, M Bermejo, Y Tsume, I Gonzalez-Alvarez, H Ruan, K Matsui, ... European Journal of Pharmaceutical Sciences 115, 258-269, 2018 | 54 | 2018 |
| FDA approval summary: tucatinib for the treatment of patients with advanced or metastatic HER2-positive breast cancer M Shah, S Wedam, J Cheng, MH Fiero, H Xia, F Li, J Fan, X Zhang, J Yu, ... Clinical Cancer Research 27 (5), 1220-1226, 2021 | 50 | 2021 |
| A multiscale physiologically-based pharmacokinetic model for doxorubicin to explore its mechanisms of cytotoxicity and cardiotoxicity in human physiological contexts H He, C Liu, Y Wu, X Zhang, J Fan, Y Cao Pharmaceutical research 35, 1-10, 2018 | 39 | 2018 |
| Bone morphogenetic protein‐4 induced rat hepatic progenitor cell (WB‐F344 cell) differentiation toward hepatocyte lineage J Fan, H Shen, Q Dai, GY Minuk, FJ Burzynski, Y Gong Journal of cellular physiology 220 (1), 72-81, 2009 | 39 | 2009 |
| Using physiologically based pharmacokinetic (PBPK) modeling to evaluate the impact of pharmaceutical excipients on oral drug absorption: sensitivity analyses ECY Chow, A Talattof, E Tsakalozou, J Fan, L Zhao, X Zhang The AAPS journal 18, 1500-1511, 2016 | 35 | 2016 |
| Gastric emptying and intestinal appearance of nonabsorbable drugs phenol red and paromomycin in human subjects: A multi-compartment stomach approach P Paixão, M Bermejo, B Hens, Y Tsume, J Dickens, K Shedden, N Salehi, ... European Journal of Pharmaceutics and Biopharmaceutics 129, 162-174, 2018 | 30 | 2018 |
