Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1 M Tahiliani, KP Koh, Y Shen, WA Pastor, H Bandukwala, Y Brudno, ... Science 324 (5929), 930-935, 2009 | 6379 | 2009 |
Complete genome sequence of the apicomplexan, Cryptosporidium parvum MS Abrahamsen, TJ Templeton, S Enomoto, JE Abrahante, G Zhu, ... Science 304 (5669), 441-445, 2004 | 1211 | 2004 |
Evolutionary history and higher order classification of AAA+ ATPases LM Iyer, DD Leipe, EV Koonin, L Aravind Journal of structural biology 146 (1-2), 11-31, 2004 | 941 | 2004 |
The many faces of the helix-turn-helix domain: transcription regulation and beyond L Aravind, V Anantharaman, S Balaji, MM Babu, LM Iyer FEMS microbiology reviews 29 (2), 231-262, 2005 | 801 | 2005 |
Evolutionary genomics of nucleo-cytoplasmic large DNA viruses LM Iyer, S Balaji, EV Koonin, L Aravind Virus research 117 (1), 156-184, 2006 | 681 | 2006 |
Common origin of four diverse families of large eukaryotic DNA viruses LM Iyer, L Aravind, EV Koonin Journal of virology 75 (23), 11720-11734, 2001 | 597 | 2001 |
Discovery of the principal specific transcription factors of Apicomplexa and their implication for the evolution of the AP2-integrase DNA binding domains S Balaji, MM Babu, LM Iyer, L Aravind Nucleic acids research 33 (13), 3994-4006, 2005 | 559 | 2005 |
Prediction of novel families of enzymes involved in oxidative and other complex modifications of bases in nucleic acids LM Iyer, M Tahiliani, A Rao, L Aravind Cell cycle 8 (11), 1698-1710, 2009 | 467 | 2009 |
Polymorphic toxin systems: comprehensive characterization of trafficking modes, processing, mechanisms of action, immunity and ecology using comparative genomics D Zhang, RF de Souza, V Anantharaman, LM Iyer, L Aravind Biology direct 7, 1-76, 2012 | 465 | 2012 |
Plasmodium biology: genomic gleanings L Aravind, LM Iyer, TE Wellems, LH Miller Cell 115 (7), 771-785, 2003 | 438 | 2003 |
Diversity and function of adaptive immune receptors in a jawless vertebrate MN Alder, IB Rogozin, LM Iyer, GV Glazko, MD Cooper, Z Pancer Science 310 (5756), 1970-1973, 2005 | 398 | 2005 |
Comparative genomics of the FtsK–HerA superfamily of pumping ATPases: implications for the origins of chromosome segregation, cell division and viral capsid packaging LM Iyer, KS Makarova, EV Koonin, L Aravind Nucleic acids research 32 (17), 5260-5279, 2004 | 338 | 2004 |
Evolution and diversification of lamprey antigen receptors: evidence for involvement of an AID-APOBEC family cytosine deaminase IB Rogozin, LM Iyer, L Liang, GV Glazko, VG Liston, YI Pavlov, L Aravind, ... Nature immunology 8 (6), 647-656, 2007 | 313 | 2007 |
Identification of the prokaryotic ligand-gated ion channels and their implications for the mechanisms and origins of animal Cys-loop ion channels A Tasneem, LM Iyer, E Jakobsson, L Aravind Genome biology 6, 1-12, 2005 | 305 | 2005 |
Comparative genomics of transcription factors and chromatin proteins in parasitic protists and other eukaryotes LM Iyer, V Anantharaman, MY Wolf, L Aravind International journal for parasitology 38 (1), 1-31, 2008 | 304 | 2008 |
Origin and evolution of the archaeo-eukaryotic primase superfamily and related palm-domain proteins: structural insights and new members LM Iyer, EV Koonin, DD Leipe, L Aravind Nucleic acids research 33 (12), 3875-3896, 2005 | 304 | 2005 |
Comprehensive analysis of combinatorial regulation using the transcriptional regulatory network of yeast S Balaji, MM Babu, LM Iyer, NM Luscombe, L Aravind Journal of molecular biology 360 (1), 213-227, 2006 | 294 | 2006 |
Discovery of novel DENN proteins: implications for the evolution of eukaryotic intracellular membrane structures and human disease D Zhang, LM Iyer, F He, L Aravind Frontiers in genetics 3, 283, 2012 | 293 | 2012 |
Comparative analysis of apicomplexa and genomic diversity in eukaryotes TJ Templeton, LM Iyer, V Anantharaman, S Enomoto, JE Abrahante, ... Genome research 14 (9), 1686-1695, 2004 | 282 | 2004 |
Evolution of cell–cell signaling in animals: did late horizontal gene transfer from bacteria have a role? LM Iyer, L Aravind, SL Coon, DC Klein, EV Koonin TRENDS in Genetics 20 (7), 292-299, 2004 | 275 | 2004 |