Cytoplasmic DRAK1 overexpressed in head and neck cancers inhibits TGF-¥â1 tumor suppressor activity by binding to Smad3 to interrupt its complex formation with Smad4 Y Park, W Kim, JM Lee, J Park, JK Cho, K Pang, J Lee, D Kim, SW Park, ... Oncogene 34 (39), 5037-5045, 2015 | 90 | 2015 |
Tetraarsenic hexoxide enhances generation of mitochondrial ROS to promote pyroptosis by inducing the activation of caspase-3/GSDME in triple-negative breast cancer cells H An, JS Heo, P Kim, Z Lian, S Lee, J Park, E Hong, K Pang, Y Park, ... Cell death & disease 12 (2), 1-15, 2021 | 53 | 2021 |
Co-chaperone BAG2 determines the pro-oncogenic role of cathepsin B in triple-negative breast cancer cells KM Yang, E Bae, SG Ahn, K Pang, Y Park, J Park, J Lee, A Ooshima, ... Cell reports 21 (10), 2952-2964, 2017 | 42 | 2017 |
RNF208, an estrogen-inducible E3 ligase, targets soluble Vimentin to suppress metastasis in triple-negative breast cancers K Pang, J Park, SG Ahn, J Lee, Y Park, A Ooshima, S Mizuno, ... Nature communications 10 (1), 1-13, 2019 | 28 | 2019 |
Destablilization of TRAF6 by DRAK1 suppresses tumor growth and metastasis in cervical cancer cells Y Park, K Pang, J Park, E Hong, J Lee, A Ooshima, HS Kim, JH Cho, ... Cancer research 80 (12), 2537-2549, 2020 | 15 | 2020 |
Galangin enhances TGF-¥â1-mediated growth inhibition by suppressing phosphorylation of threonine 179 residue in Smad3 linker region MK Kwak, KM Yang, J Park, S Lee, Y Park, E Hong, EJ Sun, H An, S Park, ... Biochemical and biophysical research communications 494 (3-4), 706-713, 2017 | 12 | 2017 |
Identification of epithelial-mesenchymal transition-related target genes induced by the mutation of Smad3 linker phosphorylation S Park, KM Yang, Y Park, E Hong, CP Hong, J Park, K Pang, J Lee, ... Journal of cancer prevention 23 (1), 1, 2018 | 11 | 2018 |
Degradation of DRAK1 by CUL3/SPOP E3 Ubiquitin ligase promotes tumor growth of paclitaxel-resistant cervical cancer cells K Pang, J Lee, J Kim, J Park, Y Park, E Hong, H An, A Ooshima, M Son, ... Cell death & disease 13 (2), 1-11, 2022 | 8 | 2022 |
ESRP1-regulated isoform switching of LRRFIP2 determines metastasis of gastric cancer J Lee, K Pang, J Kim, E Hong, J Lee, HJ Cho, J Park, M Son, S Park, ... Nature communications 13 (1), 1-15, 2022 | | 2022 |