| Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses D Anastasiou, G Poulogiannis, JM Asara, MB Boxer, J Jiang, M Shen, ... Science 334 (6060), 1278-1283, 2011 | 1214 | 2011 |
| Reprogramming of fatty acid metabolism in cancer N Koundouros, G Poulogiannis British journal of cancer 122 (1), 4-22, 2020 | 972 | 2020 |
| Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling Y Yu, SO Yoon, G Poulogiannis, Q Yang, XM Ma, J Villén, N Kubica, ... Science 332 (6035), 1322-1326, 2011 | 965 | 2011 |
| The mTORC1 pathway stimulates glutamine metabolism and cell proliferation by repressing SIRT4 A Csibi, SM Fendt, C Li, G Poulogiannis, AY Choo, DJ Chapski, SM Jeong, ... Cell 153 (4), 840-854, 2013 | 658 | 2013 |
| Asparagine bioavailability governs metastasis in a model of breast cancer SRV Knott, E Wagenblast, S Khan, SY Kim, M Soto, M Wagner, ... Nature 554 (7692), 378-381, 2018 | 448 | 2018 |
| Oncogenic KRAS regulates tumor cell signaling via stromal reciprocation CJ Tape, S Ling, M Dimitriadi, KM McMahon, JD Worboys, HS Leong, ... Cell 165 (4), 910-920, 2016 | 406 | 2016 |
| Perioperative events influence cancer recurrence risk after surgery JG Hiller, NJ Perry, G Poulogiannis, B Riedel, EK Sloan Nature reviews Clinical oncology 15 (4), 205-218, 2018 | 405 | 2018 |
| Phosphoinositide 3-kinase/Akt signaling and redox metabolism in cancer N Koundouros, G Poulogiannis Frontiers in oncology 8, 160, 2018 | 338 | 2018 |
| DNA mismatch repair deficiency in sporadic colorectal cancer and Lynch syndrome G Poulogiannis, IM Frayling, MJ Arends Histopathology 56 (2), 167-179, 2010 | 302 | 2010 |
| PARK2 deletions occur frequently in sporadic colorectal cancer and accelerate adenoma development in Apc mutant mice G Poulogiannis, RE McIntyre, M Dimitriadi, JR Apps, CH Wilson, ... Proceedings of the National Academy of Sciences 107 (34), 15145-15150, 2010 | 242 | 2010 |
| DNA damage, repair, and cancer metabolism MO Turgeon, NJS Perry, G Poulogiannis Frontiers in oncology 8, 15, 2018 | 230 | 2018 |
| Metabolic stress controls mTORC1 lysosomal localization and dimerization by regulating the TTT-RUVBL1/2 complex SG Kim, GR Hoffman, G Poulogiannis, GR Buel, YJ Jang, KW Lee, ... Molecular cell 49 (1), 172-185, 2013 | 230 | 2013 |
| Depletion of a putatively druggable class of phosphatidylinositol kinases inhibits growth of p53-null tumors BM Emerling, JB Hurov, G Poulogiannis, KS Tsukazawa, R Choo-Wing, ... Cell 155 (4), 844-857, 2013 | 182 | 2013 |
| Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance LA Martin, R Ribas, N Simigdala, E Schuster, S Pancholi, T Tenev, ... Nature communications 8 (1), 1865, 2017 | 136 | 2017 |
| PARK2 depletion connects energy and oxidative stress to PI3K/Akt activation via PTEN S-nitrosylation A Gupta, S Anjomani-Virmouni, N Koundouros, M Dimitriadi, ... Molecular cell 65 (6), 999-1013. e7, 2017 | 125 | 2017 |
| Metabolic fingerprinting links oncogenic PIK3CA with enhanced arachidonic acid-derived eicosanoids N Koundouros, E Karali, A Tripp, A Valle, P Inglese, NJS Perry, DJ Magee, ... Cell 181 (7), 1596-1611. e27, 2020 | 92 | 2020 |
| Metabolic adaptability in metastatic breast cancer by AKR1B10-dependent balancing of glycolysis and fatty acid oxidation A van Weverwijk, N Koundouros, M Iravani, M Ashenden, Q Gao, ... Nature communications 10 (1), 2698, 2019 | 91 | 2019 |
| A constitutively activated form of the p110β isoform of PI3-kinase induces prostatic intraepithelial neoplasia in mice SH Lee, G Poulogiannis, S Pyne, S Jia, L Zou, S Signoretti, M Loda, ... Proceedings of the National Academy of Sciences 107 (24), 11002-11007, 2010 | 82 | 2010 |
| Mutated K‐rasAsp12 promotes tumourigenesis in ApcMin mice more in the large than the small intestines, with synergistic effects between K‐ras and Wnt pathways F Luo, DG Brooks, H Ye, R Hamoudi, G Poulogiannis, CE Patek, ... International journal of experimental pathology 90 (5), 558-574, 2009 | 75 | 2009 |
| Identification of CDCP1 as a hypoxia-inducible factor 2α (HIF-2α) target gene that is associated with survival in clear cell renal cell carcinoma patients BM Emerling, CH Benes, G Poulogiannis, EL Bell, K Courtney, H Liu, ... Proceedings of the National Academy of Sciences 110 (9), 3483-3488, 2013 | 73 | 2013 |
Lewis CantleyDana Farber Cancer Center and Harvard Medical SchoolVerified email at med.cornell.edu
