| Redirecting abiraterone metabolism to fine-tune prostate cancer anti-androgen therapy Z Li, M Alyamani, J Li, K Rogacki, M Abazeed, SK Upadhyay, SP Balk, ... Nature 533 (7604), 547-551, 2016 | 167 | 2016 |
| Aberrant corticosteroid metabolism in tumor cells enables GR takeover in enzalutamide resistant prostate cancer J Li, M Alyamani, A Zhang, KH Chang, M Berk, Z Li, Z Zhu, M Petro, ... Elife 6, e20183, 2017 | 97 | 2017 |
| The Sp1 transcription factor is crucial for the expression of 11β-hydroxysteroid dehydrogenase type 2 in human placental trophoblasts JN Li, YC Ge, Z Yang, CM Guo, T Duan, L Myatt, H Guan, K Yang, K Sun The Journal of Clinical Endocrinology & Metabolism 96 (6), E899-E907, 2011 | 55 | 2011 |
| Role of human chorionic gonadotropin in maintaining 11β-hydroxysteroid dehydrogenase type 2 expression in human placental syncytiotrophoblasts XT Ni, T Duan, Z Yang, CM Guo, JN Li, K Sun Placenta 30 (12), 1023-1028, 2009 | 55 | 2009 |
| Steroidogenic metabolism of galeterone reveals a diversity of biochemical activities M Alyamani, Z Li, M Berk, J Li, J Tang, S Upadhyay, RJ Auchus, N Sharifi Cell chemical biology 24 (7), 825-832. e6, 2017 | 50 | 2017 |
| Discovery and mechanism study of SIRT1 activators that promote the deacetylation of fluorophore-labeled substrate J Wu, D Zhang, L Chen, J Li, J Wang, C Ning, N Yu, F Zhao, D Chen, ... Journal of Medicinal Chemistry 56 (3), 761-780, 2013 | 45 | 2013 |
| Paradoxical stimulation of cyclooxygenase-2 expression by glucocorticoids via a cyclic AMP response element in human amnion fibroblasts XO Zhu, Z Yang, CM Guo, XT Ni, JN Li, YC Ge, L Myatt, K Sun Molecular endocrinology 23 (11), 1839-1849, 2009 | 45 | 2009 |
| Functional silencing of HSD17B2 in prostate cancer promotes disease progression X Gao, C Dai, S Huang, J Tang, G Chen, J Li, Z Zhu, X Zhu, S Zhou, ... Clinical Cancer Research 25 (4), 1291-1301, 2019 | 43 | 2019 |
| Critical role of histone acetylation by p300 in human placental 11β-HSD2 expression J Li, W Wang, C Liu, W Wang, W Li, Q Shu, ZJ Chen, K Sun The Journal of Clinical Endocrinology & Metabolism 98 (7), E1189-E1197, 2013 | 42 | 2013 |
| Cross talk between cAMP and p38 MAPK pathways in the induction of leptin by hCG in human placental syncytiotrophoblasts YC Ge, JN Li, XT Ni, CM Guo, WS Wang, T Duan, K Sun Reproduction 142 (2), 369, 2011 | 40 | 2011 |
| Direct metabolic interrogation of dihydrotestosterone biosynthesis from adrenal precursors in primary prostatectomy tissues C Dai, YM Chung, E Kovac, Z Zhu, J Li, C Magi-Galluzzi, AJ Stephenson, ... Clinical Cancer Research 23 (20), 6351-6362, 2017 | 36 | 2017 |
| Cortisol induces aromatase expression in human placental syncytiotrophoblasts through the cAMP/Sp1 pathway W Wang, J Li, Y Ge, W Li, Q Shu, H Guan, K Yang, L Myatt, K Sun Endocrinology 153 (4), 2012-2022, 2012 | 32 | 2012 |
| Loss of dihydrotestosterone-inactivation activity promotes prostate cancer castration resistance detectable by functional imaging Z Zhu, YM Chung, O Sergeeva, V Kepe, M Berk, J Li, HK Ko, Z Li, M Petro, ... Journal of Biological Chemistry 293 (46), 17829-17837, 2018 | 31 | 2018 |
| Involvement of CRH and hCG in the induction of aromatase by cortisol in human placental syncytiotrophoblasts WS Wang, C Liu, WJ Li, P Zhu, JN Li, K Sun Placenta 35 (1), 30-36, 2014 | 29 | 2014 |
| H3K9 methylation drives resistance to androgen receptor–antagonist therapy in prostate cancer M Baratchian, R Tiwari, S Khalighi, A Chakravarthy, W Yuan, M Berk, J Li, ... Proceedings of the National Academy of Sciences 119 (21), e2114324119, 2022 | 23 | 2022 |
| Hexose-6-phosphate dehydrogenase blockade reverses prostate cancer drug resistance in xenograft models by glucocorticoid inactivation J Li, M Berk, M Alyamani, N Sabharwal, C Goins, J Alvarado, ... Science translational medicine 13 (595), eabe8226, 2021 | 22 | 2021 |
| Induction of Gαs Contributes to the Paradoxical Stimulation of Cytosolic Phospholipase A2α Expression by Cortisol in Human Amnion Fibroblasts C Guo, J Li, L Myatt, X Zhu, K Sun Molecular Endocrinology 24 (5), 1052-1061, 2010 | 21 | 2010 |
| Cross-talk between cAMP and MAPK pathways in HSD11B2 induction by hCG in placental trophoblasts Q Shu, W Li, J Li, W Wang, C Liu, K Sun PLoS One 9 (9), e107938, 2014 | 20 | 2014 |
| Involvement of GR and p300 in the induction of H6PD by cortisol in human amnion fibroblasts W Wang, C Guo, W Li, J Li, W Wang, L Myatt, K Sun Endocrinology 153 (12), 5993-6002, 2012 | 18 | 2012 |
| Cancer-associated fibroblast-secreted glucosamine alters the androgen biosynthesis program in prostate cancer via HSD3B1 upregulation D Cui, J Li, Z Zhu, M Berk, A Hardaway, J McManus, YM Chung, ... The Journal of clinical investigation 133 (7), 2023 | 9 | 2023 |
Kang SunProfessor, Shanghai Jiao Tong University, School of Medicine, Renji HospitalVerified email at fudan.edu.cn
