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Michael Segel
Michael Segel
postdoctoral fellow, Broad Institute
Verified email at broadinstitute.org
Title
Cited by
Cited by
Year
Generation of functional human pancreatic β cells in vitro
FW Pagliuca, JR Millman, M Gürtler, M Segel, A Van Dervort, JH Ryu, ...
Cell 159 (2), 428-439, 2014
21772014
Single-cell RNA sequencing of microglia throughout the mouse lifespan and in the injured brain reveals complex cell-state changes
TR Hammond, C Dufort, L Dissing-Olesen, S Giera, A Young, A Wysoker, ...
Immunity 50 (1), 253-271. e6, 2019
15442019
Detection of SARS-CoV-2 with SHERLOCK one-pot testing
J Joung, A Ladha, M Saito, NG Kim, AE Woolley, M Segel, RPJ Barretto, ...
New England Journal of Medicine 383 (15), 1492-1494, 2020
5962020
Niche stiffness underlies the ageing of central nervous system progenitor cells
M Segel, B Neumann, MFE Hill, IP Weber, C Viscomi, C Zhao, A Young, ...
Nature 573 (7772), 130-134, 2019
3782019
Diverse enzymatic activities mediate antiviral immunity in prokaryotes
L Gao, H Altae-Tran, F Böhning, KS Makarova, M Segel, JL Schmid-Burgk, ...
Science 369 (6507), 1077-1084, 2020
3122020
Point-of-care testing for COVID-19 using SHERLOCK diagnostics
J Joung, A Ladha, M Saito, M Segel, R Bruneau, WH Mee-li, NG Kim, ...
MedRxiv, 2020
3002020
Metformin restores CNS remyelination capacity by rejuvenating aged stem cells
B Neumann, R Baror, C Zhao, M Segel, S Dietmann, KS Rawji, S Foerster, ...
Cell stem cell 25 (4), 473-485. e8, 2019
2882019
Mammalian retrovirus-like protein PEG10 packages its own mRNA and can be pseudotyped for mRNA delivery
M Segel, B Lash, J Song, A Ladha, CC Liu, X Jin, SL Mekhedov, ...
Science 373 (6557), 882-889, 2021
2472021
A map of transcriptional heterogeneity and regulatory variation in human microglia
AMH Young, N Kumasaka, F Calvert, TR Hammond, A Knights, ...
Nature genetics 53 (6), 861-868, 2021
1352021
Remyelination and ageing: reversing the ravages of time
B Neumann, M Segel, KJ Chalut, RJM Franklin
Multiple Sclerosis Journal 25 (14), 1835-1841, 2019
842019
SC-β cells and compositions and methods for generating the same
QP Peterson, FJ Pagliuca, DA Melton, JR Millman, MS Segel, M Gurtler
US Patent 10,030,229, 2018
482018
Transforming growth factor‐beta renders ageing microglia inhibitory to oligodendrocyte generation by CNS progenitors
R Baror, B Neumann, M Segel, KJ Chalut, SPJ Fancy, DP Schafer, ...
Glia 67 (7), 1374-1384, 2019
402019
Sc-beta cells and compositions and methods for generating the same
QP Peterson, FJ Pagliuca, DA Melton, JR Millman, MS Segel, M Gürtler, ...
US Patent App. 14/898,015, 2017
362017
Sc-beta cells and compositions and methods for generating the same
QP Peterson, FJ Pagliuca, DA Melton, JR Millman, MS Segel, M Gurtler
US Patent App. 14/684,129, 2015
232015
Myc determines the functional age state of oligodendrocyte progenitor cells
B Neumann, M Segel, T Ghosh, C Zhao, P Tourlomousis, A Young, ...
Nature Aging 1 (9), 826-837, 2021
122021
Author Correction: Niche stiffness underlies the ageing of central nervous system progenitor cells
M Segel, B Neumann, MFE Hill, IP Weber, C Viscomi, C Zhao, A Young, ...
Nature 573 (7773), E3, 2019
102019
Complex cell-state changes revealed by single cell RNA sequencing of 76,149 microglia throughout the mouse lifespan and in the injured brain
TR Hammond, C Dufort, L Dissing-Olesen, S Giera, A Young, A Wysoker, ...
bioRxiv, 406140, 2018
92018
Targeted evolution of adeno-associated virus capsids for systemic transgene delivery to microglia and tissue-resident macrophages
A Young, B Neumann, M Segel, CZY Chen, P Tourlomousis, ...
Proceedings of the National Academy of Sciences 120 (35), e2302997120, 2023
52023
SC-beta cells and compositions and methods for generating the same
QP Peterson, FJ Pagliuca, DA Melton, JR Millman, MS Segel, M Gurtler
US Patent 11,078,463, 2021
52021
SC-beta cells and compositions and methods for generating the same
QP Peterson, FJ Pagliuca, DA Melton, JR Millman, MS Segel, M Gurtler
US Patent 11,162,078, 2021
42021
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