Generation and Reactions of o-Bromophenyllithium without Benzyne Formation Using a Microreactor H Usutani, Y Tomida, A Nagaki, H Okamoto, T Nokami, J Yoshida Journal of the American Chemical Society 129 (11), 3046-3047, 2007 | 288 | 2007 |
Integrated Micro Flow Synthesis Based on Sequential Br–Li Exchange Reactions of p‐, m‐, and o‐Dibromobenzenes A Nagaki, Y Tomida, H Usutani, H Kim, N Takabayashi, T Nokami, ... Chemistry–An Asian Journal 2 (12), 1513-1523, 2007 | 117 | 2007 |
Generation and reaction of cyano-substituted aryllithium compounds using microreactors A Nagaki, H Kim, H Usutani, C Matsuo, J Yoshida Organic & biomolecular chemistry 8 (5), 1212-1217, 2010 | 110 | 2010 |
Development and scale-up of a flow chemistry lithiation–borylation route to a key boronic acid starting material H Usutani, T Nihei, CD Papageorgiou, DG Cork Organic process research & development 21 (4), 669-673, 2017 | 40 | 2017 |
Effective utilization of flow chemistry: use of unstable intermediates, inhibition of side reactions, and scale-up for boronic acid synthesis H Usutani, DG Cork Organic Process Research & Development 22 (6), 741-746, 2018 | 12 | 2018 |
Application of continuous flow-flash chemistry to scale-up synthesis of 5-cyano-2-formylbenzoic acid M Seto, S Masada, H Usutani, DG Cork, K Fukuda, T Kawamoto Organic Process Research & Development 23 (7), 1420-1428, 2019 | 7 | 2019 |
Construction of a (3aR,4R,9bR)-Hexahydropyrroloquinoline by Stereoselective Hydrogen-Mediated Domino Cyclization M Yamada, H Usutani, T Ito, M Yamano Organic Process Research & Development 23 (4), 535-547, 2019 | 6 | 2019 |
Process Intensification of a Napabucasin Manufacturing Method Utilizing Microflow Chemistry H Usutani, K Yamamoto, K Hashimoto ACS omega 8 (11), 10373-10382, 2023 | 3 | 2023 |
Rapid and efficient synthesis of a novel cholinergic muscarinic M 1 receptor positive allosteric modulator using flash chemistry S Miura, K Fukuda, S Masada, H Usutani, M Kanematsu, DG Cork, ... Organic & Biomolecular Chemistry 17 (35), 8166-8174, 2019 | 3 | 2019 |
Rhodium catalyst and method for producing amine compound M Yamano, M Yamada, H Usutani US Patent 9,238,667, 2016 | 3 | 2016 |
Flow Chemistry Processes for Reactions Utilizing Unstable Intermediates: Applications Toward Pharmaceutical Production H Usutani | | 2020 |
Synthesis of a TAK-480 Fragment P Kocienski Synfacts 15 (08), 0843, 2019 | | 2019 |
Bromine-Lithium Exchange on Cyano-Substituted Arenes Using Microreactors A Nagaki, H Kim, H Usutani, C Matsuo, J Yoshida Synfacts 2010 (05), 0582-0582, 2010 | | 2010 |
Generation and reaction of cyano-substituted aryllithium compounds using microreactors J Yoshida, C Matsuo, H Kim, A Nagaki, H Usutani The Royal Society of Chemistry, 2010 | | 2010 |
Sequential integration of Br-Li exchange reactions using microflow systems Y Tomida, A Nagaki, H Usutani, H Kim, N Takabayashi, T Nokami, ... 2008 AIChE Spring National Meeting, Conference, 2008 | | 2008 |
Generation and reactions of ortho-bromophenyllithium without benzyne formation using microflow system A Nagaki, H Usutani, Y Tomida, H Kim, N Takabayashi, T Nokami, ... 10th International Conference on Microreaction Technology, IMRET 2008 …, 2008 | | 2008 |
Spotlights… A Nagaki, Y Tomida, H Usutani, H Kim, N Takabayashi, T Nokami, ... Angew. Chem. Int. Ed 46, 8936-8937, 2007 | | 2007 |
Cation Pool Method Based on CC Bond Dissociation. Effective Genergation of Monocations and Dications JI Yoshida, M Okajima, H Usutani, T Nokami, K Itami, S Suga ECS Meeting Abstracts, 951, 2006 | | 2006 |
Supplementary Material (ESI) for Organic and Biomolecular Chemistry Generation and Reaction of Cyano-Substituted Aryllithium Compounds Using Microreactors A Nagaki, H Kim, H Usutani, C Matsuo, J Yoshida | | |