| The growing applications of SuFEx click chemistry AS Barrow, CJ Smedley, Q Zheng, S Li, J Dong, JE Moses Chemical Society Reviews 48 (17), 4731-4758, 2019 | 336 | 2019 |
| Bifluoride-catalysed sulfur(VI) fluoride exchange reaction for the synthesis of polysulfates and polysulfonates B Gao, L Zhang, Q Zheng, F Zhou, LM Klivansky, J Lu, Y Liu, J Dong, ... Nature chemistry 9 (11), 1083-1088, 2017 | 230 | 2017 |
| A Heck–Matsuda Process for the Synthesis of β‐Arylethenesulfonyl Fluorides: Selectively Addressable Bis‐electrophiles for SuFEx Click Chemistry HL Qin, Q Zheng, GAL Bare, P Wu, KB Sharpless Angewandte Chemie International Edition 55 (45), 14155-14158, 2016 | 156 | 2016 |
| SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase Q Zheng, JL Woehl, S Kitamura, D Santos-Martins, CJ Smedley, G Li, ... Proceedings of the National Academy of Sciences 116 (38), 18808-18814, 2019 | 143 | 2019 |
| SuFEx‐Based Polysulfonate Formation from Ethenesulfonyl Fluoride–Amine Adducts H Wang, F Zhou, G Ren, Q Zheng, H Chen, B Gao, L Klivansky, Y Liu, ... Angewandte Chemie 129 (37), 11355-11360, 2017 | 138 | 2017 |
| Sulfur (VI) fluoride exchange (SuFEx)-enabled high-throughput medicinal chemistry S Kitamura, Q Zheng, JL Woehl, A Solania, E Chen, N Dillon, MV Hull, ... Journal of the American Chemical Society 142 (25), 10899-10904, 2020 | 109 | 2020 |
| CuI-Catalyzed C1-Alkynylation of Tetrahydroisoquinolines (THIQs) by A3 Reaction with Tunable Iminium Ions QH Zheng, W Meng, GJ Jiang, ZX Yu Organic Letters 15 (23), 5928-5931, 2013 | 105 | 2013 |
| Palladium‐Catalyzed Fluorosulfonylvinylation of Organic Iodides GF Zha, Q Zheng, J Leng, P Wu, HL Qin, KB Sharpless Angewandte Chemie International Edition 56 (17), 4849-4852, 2017 | 99 | 2017 |
| Sulfur [18F]Fluoride Exchange Click Chemistry Enabled Ultrafast Late-Stage Radiosynthesis Q Zheng, H Xu, H Wang, WGH Du, N Wang, H Xiong, Y Gu, L Noodleman, ... Journal of the American Chemical Society 143 (10), 3753-3763, 2021 | 95 | 2021 |
| Ethenesulfonyl fluoride (ESF): An on-water procedure for the kilogram-scale preparation Q Zheng, J Dong, KB Sharpless The Journal of Organic Chemistry 81 (22), 11360-11362, 2016 | 85 | 2016 |
| Bifluoride ion mediated SuFEx trifluoromethylation of sulfonyl fluorides and iminosulfur oxydifluorides CJ Smedley, Q Zheng, B Gao, S Li, A Molino, HM Duivenvoorden, ... Angewandte Chemie International Edition 58 (14), 4552-4556, 2019 | 67 | 2019 |
| KRAS is vulnerable to reversible switch-II pocket engagement in cells JD Vasta, DM Peacock, Q Zheng, JA Walker, Z Zhang, CA Zimprich, ... Nature chemical biology 18 (6), 596-604, 2022 | 56 | 2022 |
| Chemical inhibition of ENL/AF9 YEATS domains in acute leukemia L Garnar-Wortzel, TR Bishop, S Kitamura, N Milosevich, JN Asiaban, ... ACS central science 7 (5), 815-830, 2021 | 49 | 2021 |
| Mild-condition synthesis of allenes from alkynes and aldehydes mediated by tetrahydroisoquinoline (THIQ) GJ Jiang, QH Zheng, M Dou, LG Zhuo, W Meng, ZX Yu The Journal of Organic Chemistry 78 (23), 11783-11793, 2013 | 37 | 2013 |
| Quantitative and orthogonal formation and reactivity of SuFEx platforms D Gahtory, R Sen, S Pujari, S Li, Q Zheng, JE Moses, KB Sharpless, ... Chemistry–A European Journal 24 (41), 10550-10556, 2018 | 32 | 2018 |
| Aryl fluorosulfate trapped Staudinger reduction G Ren, Q Zheng, H Wang Organic letters 19 (7), 1582-1585, 2017 | 28 | 2017 |
| Drugging the next undruggable KRAS allele-Gly12Asp Q Zheng, DM Peacock, KM Shokat Journal of Medicinal Chemistry 65 (4), 3119-3122, 2022 | 27 | 2022 |
| Sulfur fluoride exchange JA Homer, L Xu, N Kayambu, Q Zheng, EJ Choi, BM Kim, KB Sharpless, ... Nature Reviews Methods Primers 3 (1), 58, 2023 | 11 | 2023 |
| Strain-release alkylation of Asp12 enables mutant selective targeting of K-Ras-G12D Q Zheng, Z Zhang, KZ Guiley, KM Shokat Nature Chemical Biology, 1-9, 2024 | 3 | 2024 |
| Nanomolar Protein Thermal Profiling with Modified Cyanine Dyes M Malakoutikhah, R Mahran, N Gooran, A Masoumi, K Lundell, ... Analytical Chemistry 95 (50), 18344-18351, 2023 | 2 | 2023 |
John E. MosesProfessor of Click ChemistryVerified email at cshl.edu
