|Oridonin, a diterpenoid extracted from medicinal herbs, targets AML1-ETO fusion protein and shows potent antitumor activity with low adverse effects on t (8; 21) leukemia in …|
GB Zhou, H Kang, L Wang, L Gao, P Liu, J Xie, FX Zhang, XQ Weng, ...
Blood 109 (8), 3441-3450, 2007
|Long-term, efficient inhibition of microRNA function in mice using rAAV vectors|
J Xie, SL Ameres, R Friedline, JH Hung, Y Zhang, Q Xie, L Zhong, Q Su, ...
Nature methods 9 (4), 403-409, 2012
|MicroRNA-regulated, systemically delivered rAAV9: a step closer to CNS-restricted transgene expression|
J Xie, Q Xie, H Zhang, SL Ameres, JH Hung, Q Su, R He, X Mu, ...
Molecular therapy 19 (3), 526-535, 2011
|A single intravenous rAAV injection as late as P20 achieves efficacious and sustained CNS Gene therapy in Canavan mice|
SS Ahmed, H Li, C Cao, EM Sikoglu, AR Denninger, Q Su, S Eaton, ...
Molecular therapy 21 (12), 2136-2147, 2013
|Novel AAV's and Uses Thereof|
G Gao, TR Flotte, J Xie
WO Patent WO2010138263 A2, 2010
|Recombinant adeno‐associated virus–mediated inhibition of microRNA‐21 protects mice against the lethal schistosome infection by repressing both IL‐13 and transforming growth …|
X He, J Xie, D Zhang, Q Su, X Sai, R Bai, C Chen, X Luo, G Gao, W Pan
Hepatology 61 (6), 2008-2017, 2015
|Short DNA hairpins compromise recombinant adeno-associated virus genome homogeneity|
J Xie, Q Mao, PWL Tai, R He, J Ai, Q Su, Y Zhu, H Ma, J Li, S Gong, ...
Molecular Therapy 25 (6), 1363-1374, 2017
|Multicistronic Expression Constructs|
G Gao, J XIE
US Patent App. PCT/US2011/033,596, 2011
|AAV-based Treatment of Cholesterol-Related Disorders|
G Gao, PD Zamore, J Xie
US Patent App. PCT/US2011/033,628, 2011
|Adenovirus–Adeno-Associated Virus Hybrid for Large-Scale Recombinant Adeno-Associated Virus Production|
H Zhang, J Xie, Q Xie, JM Wilson, G Gao
Human gene therapy 20 (9), 922-929, 2009
|AAV's and uses thereof|
G Gao, T Flotte, J Xie
US Patent 9,284,357, 2016
|Recombinant adeno-associated virus integration sites in murine liver after ornithine transcarbamylase gene correction|
L Zhong, N Malani, M Li, T Brady, J Xie, P Bell, S Li, H Jones, JM Wilson, ...
Human gene therapy 24 (5), 520-525, 2013
|Bortezomib interferes with C-KIT processing and transforms the t (8; 21)-generated fusion proteins into tumor-suppressing fragments in leukemia cells|
HT Fang, B Zhang, XF Pan, L Gao, T Zhen, HX Zhao, L Ma, J Xie, Z Liu, ...
Proceedings of the National Academy of Sciences 109 (7), 2521-2526, 2012
|Central amygdala GluA1 facilitates associative learning of opioid reward|
YQ Cai, W Wang, YY Hou, Z Zhang, J Xie, ZZ Pan
Journal of Neuroscience 33 (4), 1577-1588, 2013
|Bone-targeting AAV-mediated silencing of Schnurri-3 prevents bone loss in osteoporosis|
YS Yang, J Xie, D Wang, JM Kim, PWL Tai, E Gravallese, G Gao, JH Shim
Nature communications 10 (1), 1-13, 2019
|Adeno-associated virus genome population sequencing achieves full vector genome resolution and reveals human-vector chimeras|
PWL Tai, J Xie, K Fong, M Seetin, C Heiner, Q Su, M Weiand, D Wilmot, ...
Molecular Therapy-Methods & Clinical Development 9, 130-141, 2018
|Adeno-associated virus-mediated microRNA delivery and therapeutics|
J Xie, DR Burt, G Gao
Seminars in liver disease 35 (01), 081-088, 2015
|AAV-based treatment of cholesterol-related disorders|
G Gao, PD Zamore, J Xie
US Patent 10,202,600, 2019
|Conditional, inducible gene silencing in dopamine neurons reveals a sex-specific role for Rit2 GTPase in acute cocaine response and striatal function|
CG Sweeney, PJ Kearney, RR Fagan, LA Smith, NC Bolden, ...
Neuropsychopharmacology 45 (2), 384-393, 2020
|Chloroplast-like organelles were found in enucleate sieve elements of transgenic plants overexpressing a proteinase inhibitor|
J Xie, XZ Ouyang, KF Xia, YF Huang, WB Pan, YP Cai, X Xu, B Li, ZF Xu
Bioscience, biotechnology, and biochemistry, 0710040606-0710040606, 2007