| Diagnostic and therapeutic potential of miRNA signatures in patients with hepatocellular carcinoma F Borel, P Konstantinova, PLM Jansen Journal of hepatology 56 (6), 1371-1383, 2012 | 303 | 2012 |
| Adenosine triphosphate-binding cassette transporter genes up-regulation in untreated hepatocellular carcinoma is mediated by cellular microRNAs F Borel, R Han, A Visser, H Petry, SJH van Deventer, PLM Jansen, ... Hepatology 55 (3), 821-832, 2012 | 237 | 2012 |
| Recombinant AAV as a platform for translating the therapeutic potential of RNA interference F Borel, MA Kay, C Mueller Molecular Therapy 22 (4), 692-701, 2014 | 161 | 2014 |
| Effects of rhizobacterial ACC deaminase activity on Arabidopsis indicate that ethylene mediates local root responses to plant growth-promoting rhizobacteria C Contesto, G Desbrosses, C Lefoulon, G Béna, F Borel, M Galland, ... Plant science 175 (1-2), 178-189, 2008 | 143 | 2008 |
| Therapeutic rAAVrh10 Mediated SOD1 Silencing in Adult SOD1G93A Mice and Nonhuman Primates F Borel, G Gernoux, B Cardozo, JP Metterville, G T. Cabrera, L Song, ... Human gene therapy 27 (1), 19-31, 2016 | 118 | 2016 |
| Artificial miRNAs reduce human mutant Huntingtin throughout the striatum in a transgenic sheep model of Huntington's disease EL Pfister, N DiNardo, E Mondo, F Borel, F Conroy, C Fraser, G Gernoux, ... Human gene therapy 29 (6), 663-673, 2018 | 99 | 2018 |
| 5 Year expression and neutrophil defect repair after gene therapy in alpha-1 antitrypsin deficiency C Mueller, G Gernoux, AM Gruntman, F Borel, EP Reeves, R Calcedo, ... Molecular Therapy 25 (6), 1387-1394, 2017 | 98 | 2017 |
| Editing out five Serpina1 paralogs to create a mouse model of genetic emphysema F Borel, H Sun, M Zieger, A Cox, B Cardozo, W Li, G Oliveira, A Davis, ... Proceedings of the National Academy of Sciences 115 (11), 2788-2793, 2018 | 80 | 2018 |
| Safe and effective superoxide dismutase 1 silencing using artificial microRNA in macaques F Borel, G Gernoux, H Sun, R Stock, M Blackwood, RH Brown Jr, ... Science Translational Medicine 10 (465), eaau6414, 2018 | 74 | 2018 |
| In vivo knock-down of multidrug resistance transporters ABCC1 and ABCC2 by AAV-delivered shRNAs and by artificial miRNAs F Borel, R van Logtenstein, A Koornneef, P Maczuga, T Ritsema, H Petry, ... Journal of RNAi and gene silencing: an international journal of RNA and gene …, 2011 | 74 | 2011 |
| Survival advantage of both human hepatocyte xenografts and genome-edited hepatocytes for treatment of α-1 antitrypsin deficiency F Borel, Q Tang, G Gernoux, C Greer, Z Wang, A Barzel, MA Kay, ... Molecular Therapy 25 (11), 2477-2489, 2017 | 73 | 2017 |
| Apolipoprotein B knockdown by AAV-delivered shRNA lowers plasma cholesterol in mice A Koornneef, P Maczuga, R Van Logtenstein, F Borel, B Blits, T Ritsema, ... Molecular Therapy 19 (4), 731-740, 2011 | 58 | 2011 |
| Embedding siRNA sequences targeting apolipoprotein B100 in shRNA and miRNA scaffolds results in differential processing and in vivo efficacy P Maczuga, J Lubelski, R Van Logtenstein, F Borel, B Blits, E Fakkert, ... Molecular Therapy 21 (1), 217-227, 2013 | 49 | 2013 |
| Optimization and comparison of knockdown efficacy between polymerase II expressed shRNA and artificial miRNA targeting luciferase and Apolipoprotein B100 P Maczuga, A Koornneef, F Borel, H Petry, S van Deventer, T Ritsema, ... BMC biotechnology 12, 1-12, 2012 | 38 | 2012 |
| Safe and efficient silencing with a Pol II, but not a Pol lII, promoter expressing an artificial miRNA targeting human huntingtin EL Pfister, KO Chase, H Sun, LA Kennington, F Conroy, E Johnson, ... Molecular Therapy-Nucleic Acids 7, 324-334, 2017 | 33 | 2017 |
| Réseau Centre de Ressources Biologiques Foie (French Liver Biobanks Network), France: Adenosine triphosphate-binding cassette transporter genes up-regulation in untreated … F Borel, R Han, A Visser, H Petry, SJ Van Deventer, PL Jansen, ... Hepatology 55 (3), 821-32, 2012 | 26 | 2012 |
| Up-regulation of miR-34b/c by JNK and FOXO3 protects from liver fibrosis P Piccolo, R Ferriero, A Barbato, S Attanasio, M Monti, C Perna, F Borel, ... Proceedings of the National Academy of Sciences 118 (10), e2025242118, 2021 | 18 | 2021 |
| Therapeutic expression of hairpins targeting apolipoprotein B100 induces phenotypic and transcriptome changes in murine liver P Maczuga, J Verheij, C Van Der Loos, R Van Logtenstein, G Hooijer, ... Gene therapy 21 (1), 60-70, 2014 | 12 | 2014 |
| Design of AAV vectors for delivery of RNAi F Borel, C Mueller Adeno-Associated Virus Vectors: Design and Delivery, 3-18, 2019 | 9 | 2019 |
| Alpha-1 antitrypsin deficiency F Borel, C Mueller | 8 | 1978 |
Christian MuellerGlobal Head of Genomic Medicine -Sanofi GenzymeVerified email at sanofi.com
