Heinrich Kovar
Heinrich Kovar
Unknown affiliation
Verified email at ccri.at
Title
Cited by
Cited by
Year
Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours
O Delattre, J Zucman, B Plougastel, C Desmaze, T Melot, M Peter, ...
Nature 359 (6391), 162-165, 1992
18291992
MIC2 is a specific marker for Ewing's sarcoma and peripheral primitive neuroectodermal tumors. Evidence for a common histogenesis of Ewing's sarcoma and peripheral primitive …
IM Ambros, PF Ambros, S Strehl, H Kovar, H Gadner, M Salzer‐Kuntschik
Cancer 67 (7), 1886-1893, 1991
7101991
Ewing's sarcoma family of tumors: current management
M Bernstein, H Kovar, M Paulussen, RL Randall, A Schuck, LA Teot, ...
The oncologist 11 (5), 503-519, 2006
5392006
Ewing sarcoma: current management and future approaches through collaboration
N Gaspar, DS Hawkins, U Dirksen, IJ Lewis, S Ferrari, MC Le Deley, ...
J Clin Oncol 33 (27), 3036-3046, 2015
4342015
Does Expression of Different EWS Chimeric Transcripts Define Clinically Distinct Risk Groups of Ewing
A Zoubek, B Dockhorn-Dworniczak, O Delattre, H Christiansen, F Niggli, ...
Journal of clinical oncology 14 (4), 1245-1251, 1996
3251996
EZH2 is a mediator of EWS/FLI1 driven tumor growth and metastasis blocking endothelial and neuro-ectodermal differentiation
GHS Richter, S Plehm, A Fasan, S Rössler, R Unland, IM Bennani-Baiti, ...
Proceedings of the National Academy of Sciences 106 (13), 5324-5329, 2009
3082009
Ewing sarcoma
TGP Grünewald, F Cidre-Aranaz, D Surdez, EM Tomazou, E de Álava, ...
Nature reviews Disease primers 4 (1), 1-22, 2018
2582018
Impact of EWS-ETS fusion type on disease progression in Ewing’s sarcoma/peripheral primitive neuroectodermal tumor: prospective results from the cooperative Euro-EWING 99 trial
MC Le Deley, O Delattre, KL Schaefer, SA Burchill, G Koehler, ...
J Clin Oncol 28 (12), 1982-8, 2010
2262010
Overexpression of the pseudoautosomal gene MIC2 in Ewing's sarcoma and peripheral primitive neuroectodermal tumor.
H Kovar, M Dworzak, S Strehl, E Schnell, IM Ambros, PF Ambros, ...
Oncogene 5 (7), 1067-1070, 1990
2151990
A molecular function map of Ewing's sarcoma
M Kauer, J Ban, R Kofler, B Walker, S Davis, P Meltzer, H Kovar
PloS one 4 (4), e5415, 2009
1952009
EWS/FLI-1 antagonists induce growth inhibition of Ewing tumor cells in vitro
H Kovar, DNT Aryee, G Jug, C Henockl, M Schemper, O Delattre, ...
Cell Growth and Differentiation-Publication American Association for Cancer …, 1996
1901996
EWS-FLI1 and EWS-ERG Gene Fusions Are Associated With Similar Clinical Phenotypes in Ewing's Sarcoma
JP Ginsberg, E De Alava, M Ladanyi, LH Wexler, H Kovar, M Paulussen, ...
Journal of Clinical Oncology 17 (6), 1809-1809, 1999
1881999
Oncogenic EWS-Fli1 interacts with hsRPB7, a subunit of human RNA polymerase II
R Petermann, BM Mossier, DNT Aryee, V Khazak, EA Golemis, H Kovar
Oncogene 17 (5), 603-610, 1998
1811998
Caveolin-1 (CAV1) is a target of EWS/FLI-1 and a key determinant of the oncogenic phenotype and tumorigenicity of Ewing's sarcoma cells
OM Tirado, S Mateo-Lozano, J Villar, LE Dettin, A Llort, S Gallego, J Ban, ...
Cancer research 66 (20), 9937-9947, 2006
1742006
Among genes involved in the RB dependent cell cycle regulatory cascade, the p16 tumor suppressor gene is frequently lost in the Ewing family of tumors
H Kovar, G Jug, DNT Aryee, A Zoubek, P Ambros, B Gruber, R Windhager, ...
Oncogene 15 (18), 2225-2232, 1997
1671997
Common variants near TARDBP and EGR2 are associated with susceptibility to Ewing sarcoma
S Postel-Vinay, AS Véron, F Tirode, G Pierron, S Reynaud, H Kovar, ...
Nature genetics 44 (3), 323-327, 2012
1552012
Narrow spectrum of infrequent p53 mutations and absence of MDM2 amplification in Ewing tumours.
H Kovar, A Auinger, G Jug, D Aryee, A Zoubek, M Salzer-Kuntschik, ...
Oncogene 8 (10), 2683-2690, 1993
1461993
Epigenome mapping reveals distinct modes of gene regulation and widespread enhancer reprogramming by the oncogenic fusion protein EWS-FLI1
EM Tomazou, NC Sheffield, C Schmidl, M Schuster, A Schönegger, ...
Cell reports 10 (7), 1082-1095, 2015
1452015
DNA methylation heterogeneity defines a disease spectrum in Ewing sarcoma
NC Sheffield, G Pierron, J Klughammer, P Datlinger, A Schönegger, ...
Nature medicine 23 (3), 386-395, 2017
1402017
Fas-and activation-induced apoptosis are reduced in human T cells preactivated in the presence of TGF-beta 1.
A Cerwenka, H Kovar, O Majdic, W Holter
The Journal of Immunology 156 (2), 459-464, 1996
1271996
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