|Deployment of convalescent plasma for the prevention and treatment of COVID-19|
EM Bloch, S Shoham, A Casadevall, BS Sachais, B Shaz, JL Winters, ...
The Journal of clinical investigation 130 (6), 2757-2765, 2020
|Neutrophils employ the myeloperoxidase system to generate antimicrobial brominating and chlorinating oxidants during sepsis|
JP Gaut, GC Yeh, HD Tran, J Byun, JP Henderson, GM Richter, ...
Proceedings of the National Academy of Sciences 98 (21), 11961-11966, 2001
|Treatment and prevention of urinary tract infection with orally active FimH inhibitors|
CK Cusumano, JS Pinkner, Z Han, SE Greene, BA Ford, JR Crowley, ...
Science translational medicine 3 (109), 109ra115-109ra115, 2011
|The siderophore yersiniabactin binds copper to protect pathogens during infection|
JPH Kaveri S Chaturvedi, Chia S Hung, Jan R Crowley
Nature Chemical Biology, 2012
|Quantitative Metabolomics Reveals an Epigenetic Blueprint for Iron Acquisition in Uropathogenic Escherichia coli|
JP Henderson, JR Crowley, JS Pinkner, JN Walker, P Tsukayama, ...
PLoS pathogens 5 (2), e1000305, 2009
|Phagocytes produce 5-chlorouracil and 5-bromouracil, two mutagenic products of myeloperoxidase, in human inflammatory tissue|
JP Henderson, J Byun, J Takeshita, JW Heinecke
Journal of Biological Chemistry 278 (26), 23522-23528, 2003
|Escherichia coli biofilms have an organized and complex extracellular matrix structure|
C Hung, Y Zhou, JS Pinkner, KW Dodson, JR Crowley, J Heuser, ...
MBio 4 (5), e00645-13, 2013
|Production of brominating intermediates by myeloperoxidase: a transhalogenation pathway for generating mutagenic nucleobases during inflammation|
JP Henderson, J Byun, MV Williams, DM Mueller, ML McCormick, ...
Journal of Biological Chemistry 276 (11), 7867-7875, 2001
|Neutralizing antibody and soluble ACE2 inhibition of a replication-competent VSV-SARS-CoV-2 and a clinical isolate of SARS-CoV-2|
JB Case, PW Rothlauf, RE Chen, Z Liu, H Zhao, AS Kim, LM Bloyet, ...
Cell host & microbe 28 (3), 475-485. e5, 2020
|Molecular chlorine generated by the myeloperoxidase-hydrogen peroxide-chloride system of phagocytes produces 5-chlorocytosine in bacterial RNA|
JP Henderson, J Byun, JW Heinecke
Journal of biological chemistry 274 (47), 33440-33448, 1999
|8-Nitro-2 ‘-deoxyguanosine, a Specific Marker of Oxidation by Reactive Nitrogen Species, Is Generated by the Myeloperoxidase− Hydrogen Peroxide− Nitrite System of Activated …|
J Byun, JP Henderson, DM Mueller, JW Heinecke
Biochemistry 38 (8), 2590-2600, 1999
|Genomic diversity and fitness of E. coli strains recovered from the intestinal and urinary tracts of women with recurrent urinary tract infection|
SL Chen, M Wu, JP Henderson, TM Hooton, ME Hibbing, SJ Hultgren, ...
Science translational medicine 5 (184), 184ra60-184ra60, 2013
|Structural engineering of a phage lysin that targets Gram-negative pathogens|
P Lukacik, TJ Barnard, PW Keller, KS Chaturvedi, N Seddiki, JW Fairman, ...
Proceedings of the National Academy of Sciences 109 (25), 9857-9862, 2012
|Lead optimization studies on FimH antagonists: discovery of potent and orally bioavailable ortho-substituted biphenyl mannosides|
Z Han, JS Pinkner, B Ford, E Chorell, JM Crowley, CK Cusumano, ...
Journal of medicinal chemistry 55 (8), 3945-3959, 2012
|Pathogenic adaptations to host-derived antibacterial copper|
KS Chaturvedi, JP Henderson
Frontiers in cellular and infection microbiology 4, 3, 2014
|The heme biosynthesis pathway is essential for Plasmodium falciparum development in mosquito stage but not in blood stages|
H Ke, PA Sigala, K Miura, JM Morrisey, MW Mather, JR Crowley, ...
Journal of Biological Chemistry 289 (50), 34827-34837, 2014
|A central metabolic circuit controlled by QseC in pathogenic Escherichia coli|
M Hadjifrangiskou, M Kostakioti, SL Chen, JP Henderson, SE Greene, ...
Molecular microbiology 80 (6), 1516-1529, 2011
|Bromination of deoxycytidine by eosinophil peroxidase: a mechanism for mutagenesis by oxidative damage of nucleotide precursors|
JP Henderson, J Byun, MV Williams, ML McCormick, WC Parks, ...
Proceedings of the National Academy of Sciences 98 (4), 1631-1636, 2001
|Combinatorial small-molecule therapy prevents uropathogenic Escherichia coli catheter-associated urinary tract infections in mice|
PS Guiton, CK Cusumano, KA Kline, KW Dodson, Z Han, JW Janetka, ...
Antimicrobial agents and chemotherapy 56 (9), 4738-4745, 2012
|Cupric yersiniabactin is a virulence-associated superoxide dismutase mimic|
KS Chaturvedi, CS Hung, DE Giblin, S Urushidani, AM Austin, ...
ACS chemical biology 9 (2), 551-561, 2014