| Structural insights into µ-opioid receptor activation W Huang, A Manglik, AJ Venkatakrishnan, T Laeremans, EN Feinberg, ... Nature 524 (7565), 315-321, 2015 | 888 | 2015 |
| The novel μ‐opioid receptor agonist PZM21 depresses respiration and induces tolerance to antinociception R Hill, A Disney, A Conibear, K Sutcliffe, W Dewey, S Husbands, C Bailey, ... British journal of pharmacology 175 (13), 2653-2661, 2018 | 181 | 2018 |
| β-carboline binding to imidazoline receptors SM Husbands, RA Glennon, S Gorgerat, R Gough, R Tyacke, J Crosby, ... Drug and alcohol dependence 64 (2), 203-208, 2001 | 147 | 2001 |
| Yawning and hypothermia in rats: effects of dopamine D3 and D2 agonists and antagonists GT Collins, AH Newman, P Grundt, KC Rice, SM Husbands, ... Psychopharmacology 193, 159-170, 2007 | 142 | 2007 |
| Functional studies of specific imidazoline‐2 receptor ligands DJ Nutt, N French, S Handley, A Hudson, S Husbands, H Jackson, ... Annals of the New York Academy of Sciences 763 (1), 125-139, 1995 | 125 | 1995 |
| The orvinols and related opioids-high affinity ligands with diverse efficacy profiles JW Lewis, SM Husbands Current pharmaceutical design 10 (7), 717-732, 2004 | 108 | 2004 |
| Design and synthesis of [(2, 3-dichlorophenyl) piperazin-1-yl] alkylfluorenylcarboxamides as novel ligands selective for the dopamine D3 receptor subtype MJ Robarge, SM Husbands, A Kieltyka, R Brodbeck, A Thurkauf, ... Journal of medicinal chemistry 44 (19), 3175-3186, 2001 | 107 | 2001 |
| A novel orvinol analog, BU08028, as a safe opioid analgesic without abuse liability in primates H Ding, PW Czoty, N Kiguchi, G Cami-Kobeci, DD Sukhtankar, MA Nader, ... Proceedings of the National Academy of Sciences 113 (37), E5511-E5518, 2016 | 106 | 2016 |
| Reversible, allosteric small-molecule inhibitors of regulator of G protein signaling proteins LL Blazer, DL Roman, A Chung, MJ Larsen, BM Greedy, SM Husbands, ... Molecular pharmacology 78 (3), 524-533, 2010 | 102 | 2010 |
| Effects of atypical κ-opioid receptor agonists on intrathecal morphine-induced itch and analgesia in primates MC Ko, SM Husbands Journal of Pharmacology and Experimental Therapeutics 328 (1), 193-200, 2009 | 97 | 2009 |
| Novel Selective Compounds for the Investigation of Imidazoline Receptorsa AL Hudson, R Gough, R Tyacke, L Lione, M Lalies, J Lewis, S Husbands, ... Annals of the new York Academy of Sciences 881 (1), 81-91, 1999 | 97 | 1999 |
| Role of G protein–coupled receptor kinases 2 and 3 in μ-opioid receptor desensitization and internalization JD Lowe, HS Sanderson, AE Cooke, M Ostovar, E Tsisanova, SL Withey, ... Molecular Pharmacology 88 (2), 347-356, 2015 | 90 | 2015 |
| A nanomolar-potency small molecule inhibitor of regulator of G-protein signaling proteins LL Blazer, H Zhang, EM Casey, SM Husbands, RR Neubig Biochemistry 50 (15), 3181-3192, 2011 | 86 | 2011 |
| Microfluidic reactions using [11 C] carbon monoxide solutions for the synthesis of a positron emission tomography radiotracer S Kealey, C Plisson, TL Collier, NJ Long, SM Husbands, L Martarello, ... Organic & biomolecular chemistry 9 (9), 3313-3319, 2011 | 80 | 2011 |
| Rimcazole analogs attenuate the convulsive effects of cocaine: correlation with binding to sigma receptors rather than dopamine transporters RR Matsumoto, KL Hewett, B Pouw, WD Bowen, SM Husbands, JJ Cao, ... Neuropharmacology 41 (7), 878-886, 2001 | 76 | 2001 |
| The first universal opioid ligand,(2S)-2-[(5R, 6R, 7R, 14S)-N-cyclopropylmethyl-4, 5-epoxy-6, 14-ethano-3-hydroxy-6-methoxymorphinan-7-yl]-3, 3-dimethylpentan-2-ol (BU08028 … TV Khroyan, WE Polgar, G Cami-Kobeci, SM Husbands, NT Zaveri, L Toll Journal of Pharmacology and Experimental Therapeutics 336 (3), 952-961, 2011 | 74 | 2011 |
| Methocinnamox is a potent, long-lasting, and selective antagonist of morphine-mediated antinociception in the mouse: comparison with clocinnamox, β-funaltrexamine, and β … JH Broadbear, TL Sumpter, TF Burke, SM Husbands, JW Lewis, ... Journal of Pharmacology and Experimental Therapeutics 294 (3), 933-940, 2000 | 74 | 2000 |
| Activities of mixed NOP and μ‐opioid receptor ligands B Spagnolo, G Calo, WE Polgar, F Jiang, CM Olsen, I Berzetei‐Gurske, ... British journal of pharmacology 153 (3), 609-619, 2008 | 72 | 2008 |
| Structure−Activity Relationships at the Monoamine Transporters and σ Receptors for a Novel Series of 9-[3-(cis-3,5-Dimethyl-1-piperazinyl)-propyl]carbazole … SM Husbands, S Izenwasser, T Kopajtic, WD Bowen, BJ Vilner, JL Katz, ... Journal of medicinal chemistry 42 (21), 4446-4455, 1999 | 65 | 1999 |
| Evaluation of 11C-BU99008, a PET Ligand for the Imidazoline2 binding site in human brain RJ Tyacke, JFM Myers, A Venkataraman, I Mick, S Turton, J Passchier, ... Journal of Nuclear Medicine 59 (10), 1597-1602, 2018 | 59 | 2018 |
Newman Amy HauckNational Institue on Drug Abuse-Intramural Research Program, NIHVerified email at intra.nida.nih.gov
