Dual-color fluorescence cross-correlation spectroscopy for multicomponent diffusional analysis in solution P Schwille, FJ Meyer-Almes, R Rigler Biophysical journal 72 (4), 1878-1886, 1997 | 1140 | 1997 |
Mechanism of intercalation into the DNA double helix by ethidium FJ Meyer-Almes, D Porschke Biochemistry 32 (16), 4246-4253, 1993 | 334 | 1993 |
Fluorescence cross-correlation: a new concept for polymerase chain reaction R Rigler, Z Földes-Papp, FJ Meyer-Almes, C Sammet, M Völcker, ... Journal of biotechnology 63 (2), 97-109, 1998 | 179 | 1998 |
Fluorescence correlation spectroscopy: lead discovery by miniaturized HTS M Auer, KJ Moore, FJ Meyer-Almes, R Guenther, AJ Pope, KA Stoeckli Drug Discovery Today 3 (10), 457-465, 1998 | 151 | 1998 |
Thailandepsins: bacterial products with potent histone deacetylase inhibitory activities and broad-spectrum antiproliferative activities C Wang, LM Henkes, LB Doughty, M He, D Wang, FJ Meyer-Almes, ... Journal of natural products 74 (10), 2031-2038, 2011 | 145 | 2011 |
Defining the mechanism of action and enzymatic selectivity of psammaplin A against its epigenetic targets MGJ Baud, T Leiser, P Haus, S Samlal, AC Wong, RJ Wood, V Petrucci, ... Journal of medicinal chemistry 55 (4), 1731-1750, 2012 | 109 | 2012 |
Toward photopharmacological antimicrobial chemotherapy using photoswitchable amidohydrolase inhibitors CE Weston, A Krämer, F Colin, O Yildiz, MGJ Baud, FJ Meyer-Almes, ... ACS Infectious Diseases 3 (2), 152-161, 2017 | 95 | 2017 |
The proapoptotic influenza A virus protein PB1-F2 forms a nonselective ion channel M Henkel, D Mitzner, P Henklein, FJ Meyer-Almes, A Moroni, ... PLoS One 5 (6), e11112, 2010 | 78 | 2010 |
Repurposing approved drugs as potential inhibitors of 3CL-protease of SARS-CoV-2: Virtual screening and structure based drug design FJ Meyer-Almes Computational Biology and Chemistry 88, 107351, 2020 | 66 | 2020 |
A novel and robust homogeneous fluorescence-based assay using nanoparticles for pharmaceutical screening and diagnostics S Schaertl, FJ Meyer-Almes, E Lopez-Calle, A Siemers, J Kramer SLAS Discovery 5 (4), 227-237, 2000 | 53 | 2000 |
Enzyme Inhibition Assays Using Fluorescence Correlation Spectroscopy: A New Algorithm for the Derivation of k cat/KM and K i Values at Substrate Concentrations Much Lower than … FJ Meyer-Almes, M Auer Biochemistry 39 (43), 13261-13268, 2000 | 50 | 2000 |
Class IIa HDACs repressive activities on MEF2‐depedent transcription are associated with poor prognosis of ER+ breast tumors A Clocchiatti, E Di Giorgio, S Ingrao, FJ Meyer‐Almes, C Tripodo, ... The FASEB Journal 27 (3), 942-954, 2013 | 49 | 2013 |
Discovery of 5-naphthylidene-2, 4-thiazolidinedione derivatives as selective HDAC8 inhibitors and evaluation of their cytotoxic effects in leukemic cell lines K Tilekar, N Upadhyay, N Jänsch, M Schweipert, P Mrowka, ... Bioorganic chemistry 95, 103522, 2020 | 42 | 2020 |
Discovery of novel N-substituted thiazolidinediones (TZDs) as HDAC8 inhibitors: in-silico studies, synthesis, and biological evaluation N Upadhyay, K Tilekar, N Jänsch, M Schweipert, JD Hess, LH Macias, ... Bioorganic chemistry 100, 103934, 2020 | 41 | 2020 |
The enzyme activity of histone deacetylase 8 is modulated by a redox-switch N Jänsch, C Meyners, M Muth, A Kopranovic, O Witt, I Oehme, ... Redox Biology 20, 60-67, 2019 | 39 | 2019 |
Histone deacetylase inhibitor assay based on fluorescence resonance energy transfer D Riester, C Hildmann, A Schwienhorst, FJ Meyer-Almes Analytical biochemistry 362 (1), 136-141, 2007 | 39 | 2007 |
Identification of novel small-molecule histone deacetylase inhibitors by medium-throughput screening using a fluorigenic assay D Wegener, C Hildmann, D Riester, A Schober, FJ Meyer-Almes, ... Biochemical Journal 413 (1), 143-150, 2008 | 35 | 2008 |
Potent and selective non‐hydroxamate histone deacetylase 8 inhibitors A Kleinschek, C Meyners, E Digiorgio, C Brancolini, FJ Meyer‐Almes ChemMedChem 11 (23), 2598-2606, 2016 | 34 | 2016 |
Thioester derivatives of the natural product psammaplin A as potent histone deacetylase inhibitors MGJ Baud, T Leiser, V Petrucci, M Gunaratnam, S Neidle, ... Beilstein Journal of Organic Chemistry 9 (1), 81-88, 2013 | 34 | 2013 |
Pharmacophore hybridization approach to discover novel pyrazoline-based hydantoin analogs with anti-tumor efficacy N Upadhyay, K Tilekar, F Loiodice, NY Anisimova, TS Spirina, ... Bioorganic Chemistry 107, 104527, 2021 | 33 | 2021 |