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Nicole Maphis
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Reactive microglia drive tau pathology and contribute to the spreading of pathological tau in the brain
N Maphis, G Xu, ON Kokiko-Cochran, S Jiang, A Cardona, RM Ransohoff, ...
Brain 138 (6), 1738-1755, 2015
4842015
Microglial derived tumor necrosis factor-α drives Alzheimer's disease-related neuronal cell cycle events
K Bhaskar, N Maphis, G Xu, NH Varvel, ON Kokiko-Cochran, JP Weick, ...
Neurobiology of disease 62, 273-285, 2014
1692014
Pharmaceutical screen identifies novel target processes for activation of autophagy with a broad translational potential
S Chauhan, Z Ahmed, SB Bradfute, J Arko-Mensah, MA Mandell, ...
Nature communications 6 (1), 8620, 2015
1522015
Selective suppression of the α isoform of p38 MAPK rescues late-stage tau pathology
N Maphis, S Jiang, G Xu, ON Kokiko-Cochran, SM Roy, LJ Van Eldik, ...
Alzheimer's research & therapy 8, 1-15, 2016
1052016
Loss of tau rescues inflammation-mediated neurodegeneration
N Maphis, G Xu, ON Kokiko-Cochran, AE Cardona, RM Ransohoff, ...
Frontiers in neuroscience 9, 146270, 2015
892015
Hypoxia promotes tau hyperphosphorylation with associated neuropathology in vascular dysfunction
L Raz, K Bhaskar, J Weaver, S Marini, Q Zhang, JF Thompson, ...
Neurobiology of disease 126, 124-136, 2019
752019
Proteopathic tau primes and activates interleukin-1β via myeloid-cell-specific MyD88-and NLRP3-ASC-inflammasome pathway
S Jiang, NM Maphis, J Binder, D Chisholm, L Weston, W Duran, ...
Cell reports 36 (12), 2021
492021
Qß Virus-like particle-based vaccine induces robust immunity and protects against tauopathy
NM Maphis, J Peabody, E Crossey, S Jiang, FA Jamaleddin Ahmad, ...
npj Vaccines 4 (1), 26, 2019
372019
Photoreceptor degeneration, azoospermia, leukoencephalopathy, and abnormal RPE cell function in mice expressing an early stop mutation in CLCN2
MM Edwards, CM de Evsikova, GB Collin, E Gifford, J Wu, WL Hicks, ...
Investigative ophthalmology & visual science 51 (6), 3264-3272, 2010
302010
Whole genome expression analysis in a mouse model of tauopathy identifies MECP2 as a possible regulator of tau pathology
NM Maphis, S Jiang, J Binder, C Wright, B Gopalan, BT Lamb, K Bhaskar
Frontiers in molecular neuroscience 10, 69, 2017
292017
Machine learning prediction and tau-based screening identifies potential Alzheimer’s disease genes relevant to immunity
J Binder, O Ursu, C Bologa, S Jiang, N Maphis, S Dadras, D Chisholm, ...
Communications Biology 5 (1), 125, 2022
272022
Genetically enhancing the expression of chemokine domain of CX3CL1 fails to prevent tau pathology in mouse models of tauopathy
SM Bemiller, NM Maphis, SV Formica, GN Wilson, CM Miller, G Xu, ...
Journal of Neuroinflammation 15, 1-11, 2018
192018
The development, but not expression, of alcohol front‐loading in C57BL/6J mice maintained on LabDiet 5001 is abolished by maintenance on Teklad 2920x rodent diet
NM Maphis, RT Huffman, DN Linsenbardt
Alcoholism: Clinical and Experimental Research 46 (7), 1321-1330, 2022
122022
Selective In Vitro and Ex Vivo Staining of Brain Neurofibrillary Tangles and Amyloid Plaques by Novel Ethylene Ethynylene-Based Optical Sensors
FA Monge, AM Fanni, PL Donabedian, J Hulse, NM Maphis, S Jiang, ...
Biosensors 13 (2), 151, 2023
12023
Binding-Activated Superradiant Probes for Amyloid in Solution and Tissue
P Donabedian, N Maphis, S Jiang, K Bhaskar, D Whitten, E Chi
Biophysical Journal 110 (3), 554a, 2016
12016
Virus-like particle (VLP)-based vaccine targeting tau phosphorylated at Ser396/Ser404 (PHF1) site outperforms phosphorylated S199/S202 (AT8) site in reducing tau pathology and …
JP Hulse, NM Maphis, J Peabody, B Chackerian, K Bhaskar
bioRxiv, 2024.04. 05.588338, 2024
2024
Alcohol Consumption During Early Adulthood in a Preclinical Mouse Model of Alzheimer’s Disease Leads to Gait Impairments, Dysregulated Circadian Rhythm, Alterations in …
NM Maphis, D Furlano, SA David, DN Linsebardt
2023
Comparison of Novel Virus-Like Particle Vaccines Against Tau in a Mouse Model of Alzheimer’s Disease
J Hulse, N Maphis, J Peabody, B Chackerian, K Bhaskar
2023
THE USE OF A TOUCHSCREEN-BASED OPERANT PARADIGM TO ASSESS THE EFFECTS OF PRENATAL ALCOHOL EXPOSURE ON RISK-TAKING BEHAVIOR IN MICE
A Myrick, NM Maphis, D Furlano, Z Villasenor, A Moore, M Orozco, ...
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH 46, 197A-197A, 2022
2022
C57BL/6J MICE MAINTAINED ON TWO DIFFERENT COMMON RODENT DIETS DISPLAY DIFFERENCES IN BINGE ALCOHOL CONSUMPTION DUE TO DIFFERENCES IN FRONT-LOADING BEHAVIOR
NM Maphis, TR Huffman, DN Linsenbardt
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH 46, 192A-192A, 2022
2022
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