Real-time evolution of new genes by innovation, amplification, and divergence J Näsvall, L Sun, JR Roth, DI Andersson Science 338, 384–387, 2012 | 266 | 2012 |
Evolution of new functions de novo and from preexisting genes DI Andersson, J Jerlström-Hultqvist, J Näsvall Cold Spring Harbor Perspectives in Biology 7 (6), a017996, 2015 | 155 | 2015 |
The modified wobble nucleoside uridine-5-oxyacetic acid in tRNAProcmo5UGG promotes reading of all four proline codons in vivo SJ NÄSVALL, P Chen, GR BJÖRK Rna 10 (10), 1662-1673, 2004 | 136 | 2004 |
Evolution of antibiotic resistance without antibiotic exposure A Knöppel, J Näsvall, DI Andersson Antimicrobial agents and chemotherapy 61 (11), 10.1128/aac. 01495-17, 2017 | 123 | 2017 |
Activation of cryptic aminoglycoside resistance in Salmonella enterica S Koskiniemi, M Pränting, E Gullberg, J Näsvall, DI Andersson Molecular microbiology 80 (6), 1464-1478, 2011 | 112 | 2011 |
The wobble hypothesis revisited: uridine-5-oxyacetic acid is critical for reading of G-ending codons SJ Näsvall, P Chen, GR Björk Rna 13 (12), 2151-2164, 2007 | 104 | 2007 |
Genetic adaptation to growth under laboratory conditions in Escherichia coli and Salmonella enterica A Knöppel, M Knopp, LM Albrecht, E Lundin, U Lustig, J Näsvall, ... Frontiers in microbiology 9, 347443, 2018 | 79 | 2018 |
Minor fitness costs in an experimental model of horizontal gene transfer in bacteria A Knöppel, PA Lind, U Lustig, J Näsvall, DI Andersson Molecular biology and evolution 31 (5), 1220-1227, 2014 | 54 | 2014 |
A'gain of function'mutation in a protein mediates production of novel modified nucleosides P Chen, PF Crain, SJ Näsvall, SC Pomerantz, GR Björk The EMBO journal 24 (10), 1842-1851, 2005 | 49 | 2005 |
Compensating the fitness costs of synonymous mutations A Knöppel, J Näsvall, DI Andersson Molecular biology and evolution 33 (6), 1461-1477, 2016 | 46 | 2016 |
Duplication-insertion recombineering: a fast and scar-free method for efficient transfer of multiple mutations in bacteria J Näsvall, A Knöppel, DI Andersson Nucleic acids research 45 (5), e33-e33, 2017 | 40 | 2017 |
Structural mechanism of AadA, a dual-specificity aminoglycoside adenylyltransferase from Salmonella enterica AL Stern, SE Van der Verren, J Näsvall, H Gutiérrez-de-Terán, M Selmer Journal of Biological Chemistry 293 (29), 11481-11490, 2018 | 34 | 2018 |
The ribosomal grip of the peptidyl-tRNA is critical for reading frame maintenance SJ Näsvall, K Nilsson, GR Björk Journal of molecular biology 385 (2), 350-367, 2009 | 34 | 2009 |
Structural and functional innovations in the real-time evolution of new (βα) 8 barrel enzymes MS Newton, X Guo, A Söderholm, J Näsvall, P Lundström, DI Andersson, ... Proceedings of the National Academy of Sciences 114 (18), 4727-4732, 2017 | 29 | 2017 |
Direct and Inverted Repeat stimulated excision (DIRex): Simple, single-step, and scar-free mutagenesis of bacterial genes J Näsvall PLOS One 12 (8), e0184126, 2017 | 21 | 2017 |
Experimental determination and prediction of the fitness effects of random point mutations in the biosynthetic enzyme HisA E Lundin, PC Tang, L Guy, J Näsvall, DI Andersson Molecular biology and evolution 35 (3), 704-718, 2018 | 19 | 2018 |
Structure of AadA from Salmonella enterica: a monomeric aminoglycoside (3′′)(9) adenyltransferase Y Chen, J Näsvall, S Wu, DI Andersson, M Selmer Acta Crystallographica Section D: Biological Crystallography 71 (11), 2267-2277, 2015 | 18 | 2015 |
Two-step ligand binding in a (βα)8 barrel enzyme – substrate-bound structures shed new light on the catalytic cycle of HisA A Söderholm, X Guo, MS Newton, GB Evans, J Näsvall, WM Patrick, ... Journal of Biological Chemistry, 2015 | 17 | 2015 |
Two groups of phenylalanine biosynthetic operon leader peptides genes: a high level of apparently incidental frameshifting in decoding Escherichia coli pheL OL Gurvich, SJ Näsvall, PV Baranov, GR Björk, JF Atkins Nucleic acids research 39 (8), 3079-3092, 2011 | 14 | 2011 |
Evolution of new functions de novo and from preexisting genes. Cold Spring Harb Perspect Biol 7: a017996 DI Andersson, J Jerlström-Hultqvist, J Näsvall | 10 | 2015 |