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Matthew Dunworth
Matthew Dunworth
Graduate Student, Johns Hopkins Medicine
Verified email at jhmi.edu
Title
Cited by
Cited by
Year
Whole genome comparison of a large collection of mycobacteriophages reveals a continuum of phage genetic diversity
WH Pope, CA Bowman, DA Russell, D Jacobs-Sera, DJ Asai, ...
elife 4, e06416, 2015
2962015
An expanded universe of cancer targets
WC Hahn, JS Bader, TP Braun, A Califano, PA Clemons, BJ Druker, ...
Cell 184 (5), 1142-1155, 2021
1532021
Cancer cells educate natural killer cells to a metastasis-promoting cell state
IS Chan, H Knútsdóttir, G Ramakrishnan, V Padmanaban, M Warrier, ...
Journal of Cell Biology 219 (9), 2020
1022020
DFMO and 5-azacytidine increase M1 macrophages in the tumor microenvironment of murine ovarian cancer
M Travers, SM Brown, M Dunworth, CE Holbert, KR Wiehagen, ...
Cancer research 79 (13), 3445-3454, 2019
712019
Triple-negative breast cancer metastasis involves complex epithelial-mesenchymal transition dynamics and requires vimentin
EM Grasset, M Dunworth, G Sharma, M Loth, J Tandurella, ...
Science translational medicine 14 (656), eabn7571, 2022
562022
Polyamine homeostasis in Snyder-Robinson syndrome
T Murray-Stewart, M Dunworth, JR Foley, CE Schwartz, RA Casero Jr
Medical sciences 6 (4), 112, 2018
422018
Activation of endoplasmic reticulum stress response by enhanced polyamine catabolism is important in the mediation of cisplatin-induced acute kidney injury
K Zahedi, S Barone, C Destefano-Shields, M Brooks, T Murray-Stewart, ...
PLoS One 12 (9), e0184570, 2017
342017
Curcumin mediates polyamine metabolism and sensitizes gastrointestinal cancer cells to antitumor polyamine-targeted therapies
T Murray-Stewart, M Dunworth, Y Lui, FM Giardiello, PM Woster, ...
PLoS One 13 (8), e0202677, 2018
322018
Autophagy induction by exogenous polyamines is an artifact of bovine serum amine oxidase activity in culture serum
CE Holbert, M Dunworth, JR Foley, TT Dunston, TM Stewart, RA Casero
Journal of Biological Chemistry 295 (27), 9061-9068, 2020
272020
DOT1L is a novel cancer stem cell target for triple-negative breast cancer
H Kurani, SF Razavipour, KB Harikumar, M Dunworth, AJ Ewald, A Nasir, ...
Clinical cancer research 28 (9), 1948-1965, 2022
252022
Dual inhibitors of LSD1 and spermine oxidase
S Holshouser, M Dunworth, T Murray-Stewart, YK Peterson, P Burger, ...
MedChemComm 10 (5), 778-790, 2019
222019
Engineering a 3D collective cancer invasion model with control over collagen fiber alignment
CY Su, A Burchett, M Dunworth, JS Choi, AJ Ewald, EH Ahn, DH Kim
Biomaterials 275, 120922, 2021
182021
Metabolomic studies identify changes in transmethylation and polyamine metabolism in a brain-specific mouse model of tuberous sclerosis complex
J McKenna III, D Kapfhamer, JM Kinchen, B Wasek, M Dunworth, ...
Human molecular genetics 27 (12), 2113-2124, 2018
152018
Polymeric prodrugs targeting polyamine metabolism inhibit Zika virus replication
NK Routhu, Y Xie, M Dunworth, RA Casero Jr, D Oupicky, SN Byrareddy
Molecular pharmaceutics 15 (9), 4284-4295, 2018
112018
Hyperglycemic conditions proliferate triple negative breast cancer cells: role of ornithine decarboxylase
CC Capellen, J Ortega-Rodas, MJ Morwitzer, HMN Tofilau, M Dunworth, ...
Breast cancer research and treatment 190, 255-264, 2021
82021
A new class of cytotoxic agents targets tubulin and disrupts microtubule dynamics
AA Al-Hamashi, R Koranne, S Dlamini, A Alqahtani, E Karaj, MS Rashid, ...
Bioorganic chemistry 116, 105297, 2021
82021
Ablation of polyamine catabolic enzymes provokes Purkinje cell damage, neuroinflammation, and severe ataxia
K Zahedi, M Brooks, S Barone, N Rahmati, T Murray Stewart, M Dunworth, ...
Journal of neuroinflammation 17, 1-21, 2020
82020
Triple negative breast tumors contain heterogeneous cancer cells expressing distinct KRAS-dependent collective and disseminative invasion programs
E Henriet, H Knutsdottir, EM Grasset, M Dunworth, M Haynes, JS Bader, ...
Oncogene 42 (10), 737-747, 2023
72023
Elevation of cellular Mg2+ levels by the Mg2+ transporter, Alr1, supports growth of polyamine-deficient Saccharomyces cerevisiae cells
AS Hanner, M Dunworth, RA Casero, CW MacDiarmid, MH Park
Journal of Biological Chemistry 294 (45), 17131-17142, 2019
42019
Intra-and Interpatient Drug Response Heterogeneity Exist in Patients Undergoing Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Nongynecologic Cancers
SN Radomski, M Dunworth, JJ West, JB Greer, FM Johnston, AJ Ewald
Annals of surgical oncology 31 (3), 1996-2007, 2024
12024
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Articles 1–20