Brian Bierie
Brian Bierie
Verified email at wi.mit.edu
Title
Cited by
Cited by
Year
TGFβ: the molecular Jekyll and Hyde of cancer
B Bierie, HL Moses
Nature Reviews Cancer 6 (7), 506-520, 2006
13992006
Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state
CL Chaffer, I Brueckmann, C Scheel, AJ Kaestli, PA Wiggins, ...
Proceedings of the National Academy of Sciences 108 (19), 7950-7955, 2011
11182011
Recovering gene interactions from single-cell data using data diffusion
D Van Dijk, R Sharma, J Nainys, K Yim, P Kathail, AJ Carr, C Burdziak, ...
Cell 174 (3), 716-729. e27, 2018
5312018
TGF-β and cancer
B Bierie, HL Moses
Cytokine & growth factor reviews 17 (1-2), 29-40, 2006
5242006
Transforming growth factor beta (TGF-β) and inflammation in cancer
B Bierie, HL Moses
Cytokine & growth factor reviews 21 (1), 49-59, 2010
3552010
Effect of conditional knockout of the type II TGF-β receptor gene in mammary epithelia on mammary gland development and polyomavirus middle T antigen induced tumor formation …
E Forrester, A Chytil, B Bierie, M Aakre, AE Gorska, AR Sharif-Afshar, ...
Cancer research 65 (6), 2296-2302, 2005
2952005
Protein kinase C α is a central signaling node and therapeutic target for breast cancer stem cells
WL Tam, H Lu, J Buikhuisen, BS Soh, E Lim, F Reinhardt, ZJ Wu, JA Krall, ...
Cancer cell 24 (3), 347-364, 2013
2772013
Inhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma
H Ijichi, A Chytil, AE Gorska, ME Aakre, B Bierie, M Tada, D Mohri, ...
The Journal of clinical investigation 121 (10), 4106-4117, 2011
2352011
Activation of PKA leads to mesenchymal-to-epithelial transition and loss of tumor-initiating ability
DR Pattabiraman, B Bierie, KI Kober, P Thiru, JA Krall, C Zill, F Reinhardt, ...
Science 351 (6277), 2016
2162016
A delicate balance: TGF‐β and the tumor microenvironment
DG Stover, B Bierie, HL Moses
Journal of cellular biochemistry 101 (4), 851-861, 2007
1772007
The systemic response to surgery triggers the outgrowth of distant immune-controlled tumors in mouse models of dormancy
JA Krall, F Reinhardt, OA Mercury, DR Pattabiraman, MW Brooks, ...
Science translational medicine 10 (436), 2018
1762018
Integrin-β4 identifies cancer stem cell-enriched populations of partially mesenchymal carcinoma cells
B Bierie, SE Pierce, C Kroeger, DG Stover, DR Pattabiraman, P Thiru, ...
Proceedings of the National Academy of Sciences 114 (12), E2337-E2346, 2017
1662017
Acquisition of a hybrid E/M state is essential for tumorigenicity of basal breast cancer cells
C Kröger, A Afeyan, J Mraz, EN Eaton, F Reinhardt, YL Khodor, P Thiru, ...
Proceedings of the National Academy of Sciences 116 (15), 7353-7362, 2019
1582019
Dihydropyrimidine accumulation is required for the epithelial-mesenchymal transition
YD Shaul, E Freinkman, WC Comb, JR Cantor, WL Tam, P Thiru, D Kim, ...
Cell 158 (5), 1094-1109, 2014
1562014
Abrogation of TGF-β signaling enhances chemokine production and correlates with prognosis in human breast cancer
B Bierie, CH Chung, JS Parker, DG Stover, N Cheng, A Chytil, M Aakre, ...
The Journal of clinical investigation 119 (6), 1571-1582, 2009
1512009
Deletion of Stat3 blocks mammary gland involution and extends functional competence of the secretory epithelium in the absence of lactogenic stimuli
RC Humphreys, B Bierie, L Zhao, R Raz, D Levy, L Hennighausen
Endocrinology 143 (9), 3641-3650, 2002
1502002
Activation of β-catenin in prostate epithelium induces hyperplasias and squamous transdifferentiation
B Bierie, M Nozawa, JP Renou, JM Shillingford, F Morgan, T Oka, ...
Oncogene 22 (25), 3875-3887, 2003
1472003
Transforming growth factor–β regulates mammary carcinoma cell survival and interaction with the adjacent microenvironment
B Bierie, DG Stover, TW Abel, A Chytil, AE Gorska, M Aakre, E Forrester, ...
Cancer research 68 (6), 1809-1819, 2008
1362008
Targeted expression of HGF/SF in mouse mammary epithelium leads to metastatic adenosquamous carcinomas through the activation of multiple signal transduction pathways
MI Gallego, B Bierie, L Hennighausen
Oncogene 22 (52), 8498-8508, 2003
1202003
C/EBPδ is a crucial regulator of pro-apoptotic gene expression during mammary gland involution
M Thangaraju, M Rudelius, B Bierie, M Raffeld, S Sharan, ...
Development 132 (21), 4675-4685, 2005
1112005
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