Genetic basis for clinical response to CTLA-4 blockade in melanoma A Snyder, V Makarov, T Merghoub, J Yuan, JM Zaretsky, A Desrichard, ... New England Journal of Medicine 371 (23), 2189-2199, 2014 | 3981 | 2014 |
IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype S Turcan, D Rohle, A Goenka, LA Walsh, F Fang, E Yilmaz, C Campos, ... Nature 483 (7390), 479-483, 2012 | 1909 | 2012 |
The mutational landscape of adenoid cystic carcinoma AS Ho, K Kannan, DM Roy, LGT Morris, I Ganly, N Katabi, D Ramaswami, ... Nature genetics 45 (7), 791-798, 2013 | 402 | 2013 |
Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation LGT Morris, AM Kaufman, Y Gong, D Ramaswami, LA Walsh, Ş Turcan, ... Nature genetics 45 (3), 253-261, 2013 | 389 | 2013 |
Obesity alters the lung myeloid cell landscape to enhance breast cancer metastasis through IL5 and GM-CSF DF Quail, OC Olson, P Bhardwaj, LA Walsh, L Akkari, ML Quick, IC Chen, ... Nature cell biology 19 (8), 974-987, 2017 | 186 | 2017 |
Driver mutations of cancer epigenomes DM Roy, LA Walsh, TA Chan Protein & cell 5 (4), 265-296, 2014 | 159 | 2014 |
Comprehensive Molecular Characterization of Salivary Duct Carcinoma Reveals Actionable Targets and Similarity to Apocrine Breast CancerMolecular Characterization of Salivary … MG Dalin, A Desrichard, N Katabi, V Makarov, LA Walsh, KW Lee, ... Clinical cancer research 22 (18), 4623-4633, 2016 | 144 | 2016 |
Primary tumors induce neutrophil extracellular traps with targetable metastasis-promoting effects RF Rayes, JG Mouhanna, I Nicolau, F Bourdeau, B Giannias, S Rousseau, ... JCI insight 4 (16), 2019 | 138 | 2019 |
Recurrent SERPINB3 and SERPINB4 mutations in patients who respond to anti-CTLA4 immunotherapy N Riaz, JJ Havel, SM Kendall, V Makarov, LA Walsh, A Desrichard, ... Nature genetics 48 (11), 1327-1329, 2016 | 120 | 2016 |
Rapamycin suppresses self-renewal and vasculogenic potential of stem cells isolated from infantile hemangioma S Greenberger, S Yuan, LA Walsh, E Boscolo, KT Kang, B Matthews, ... Journal of investigative dermatology 131 (12), 2467-2476, 2011 | 115 | 2011 |
IGF-1 increases invasive potential of MCF 7 breast cancer cells and induces activation of latent TGF-β1 resulting in epithelial to mesenchymal transition LA Walsh, S Damjanovski Cell Communication and Signaling 9, 1-11, 2011 | 115 | 2011 |
Discoidin domain receptor 2 is a critical regulator of epithelial–mesenchymal transition LA Walsh, A Nawshad, D Medici Matrix Biology 30 (4), 243-247, 2011 | 89 | 2011 |
An integrated systems biology approach identifies TRIM25 as a key determinant of breast cancer metastasis LA Walsh, MJ Alvarez, EY Sabio, M Reyngold, V Makarov, S Mukherjee, ... Cell reports 20 (7), 1623-1640, 2017 | 83 | 2017 |
Microenvironmental heterogeneity in brain malignancies LJM Perus, LA Walsh Frontiers in immunology 10, 2294, 2019 | 59 | 2019 |
Multi-dimensional genomic analysis of myoepithelial carcinoma identifies prevalent oncogenic gene fusions MG Dalin, N Katabi, M Persson, KW Lee, V Makarov, A Desrichard, ... Nature communications 8 (1), 1197, 2017 | 59 | 2017 |
Candidate prognostic markers in breast cancer: focus on extracellular proteases and their inhibitors DM Roy, LA Walsh Breast Cancer: Targets and Therapy, 81-91, 2014 | 57 | 2014 |
Embryonic morphogen nodal promotes breast cancer growth and progression DF Quail, G Zhang, LA Walsh, GM Siegers, DZ Dieters-Castator, ... PloS one 7 (11), e48237, 2012 | 47 | 2012 |
Remodeling of the methylation landscape in breast cancer metastasis M Reyngold, S Turcan, D Giri, K Kannan, LA Walsh, A Viale, M Drobnjak, ... PloS one 9 (8), e103896, 2014 | 46 | 2014 |
Embryonic protein nodal promotes breast cancer vascularization DF Quail, LA Walsh, G Zhang, SD Findlay, J Moreno, L Fung, A Ablack, ... Cancer research 72 (15), 3851-3863, 2012 | 46 | 2012 |
Low oxygen levels induce the expression of the embryonic morphogen Nodal DF Quail, MJ Taylor, LA Walsh, D Dieters-Castator, P Das, M Jewer, ... Molecular biology of the cell 22 (24), 4809-4821, 2011 | 46 | 2011 |