David Gnutt
David Gnutt
Bayer AG
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Cited by
Excluded‐Volume Effects in Living Cells
D Gnutt, M Gao, O Brylski, M Heyden, S Ebbinghaus
Angewandte Chemie International Edition 54 (8), 2548-2551, 2015
Effects of in vivo conditions on amyloid aggregation
MC Owen, D Gnutt, M Gao, SKTS Wärmländer, J Jarvet, A Gräslund, ...
Chemical Society Reviews 48 (14), 3946-3996, 2019
The macromolecular crowding effect–from in vitro into the cell
D Gnutt, S Ebbinghaus
Biological chemistry 397 (1), 37-44, 2016
RNA Hairpin Folding in the Crowded Cell
M Gao, D Gnutt, A Orban, B Appel, F Righetti, R Winter, F Narberhaus, ...
Angewandte Chemie International Edition 55 (9), 3224-3228, 2016
Stability effect of quinary interactions reversed by single point mutations
D Gnutt, S Timr, J Ahlers, B König, E Manderfeld, M Heyden, F Sterpone, ...
Journal of the American Chemical Society 141 (11), 4660-4669, 2019
Optimizing the Cell Painting assay for image-based profiling
BA Cimini, SN Chandrasekaran, M Kost-Alimova, L Miller, A Goodale, ...
Nature protocols 18 (7), 1981-2013, 2023
Inhibition of huntingtin exon-1 aggregation by the molecular tweezer CLR01
T Vöpel, K Bravo-Rodriguez, S Mittal, S Vachharajani, D Gnutt, ...
Journal of the American Chemical Society 139 (16), 5640-5643, 2017
JUMP Cell Painting dataset: morphological impact of 136,000 chemical and genetic perturbations
SN Chandrasekaran, J Ackerman, E Alix, DM Ando, J Arevalo, M Bennion, ...
bioRxiv, 2023.03. 23.534023, 2023
Conformational dynamics and self-association of intrinsically disordered Huntingtin exon 1 in cells
S Büning, A Sharma, S Vachharajani, E Newcombe, A Ormsby, M Gao, ...
Physical Chemistry Chemical Physics 19 (17), 10738-10747, 2017
Imperfect crowding adaptation of mammalian cells towards osmotic stress and its modulation by osmolytes
D Gnutt, O Brylski, E Edengeiser, M Havenith, S Ebbinghaus
Molecular BioSystems 13 (11), 2218-2221, 2017
Role of Electrostatics in Protein–RNA Binding: The Global vs the Local Energy Landscape
Z Ghaemi, I Guzman, D Gnutt, Z Luthey-Schulten, M Gruebele
The Journal of Physical Chemistry B 121 (36), 8437-8446, 2017
The Unfolding Journey of Superoxide Dismutase 1 Barrels Under Crowding: Atomistic Simulations Shed Light on Intermediate States and Their Interactions With Crowders
S Timr, D Gnutt, S Ebbinghaus, F Sterpone
The journal of physical chemistry letters 11 (10), 4206-4212, 2020
Cryo-EM structural studies of the agonist complexed human TRPV4 ion-channel reveals novel structural rearrangements resulting in an open-conformation
M Botte, AKC Ulrich, R Adaixo, D Gnutt, A Brockmann, D Bucher, ...
BioRxiv, 2020.10. 13.334797, 2020
Protein folding modulation in cells subject to differentiation and stress
D Gnutt, L Sistemich, S Ebbinghaus
Frontiers in molecular biosciences 6, 38, 2019
Self-supervision advances morphological profiling by unlocking powerful image representations
V Kim, N Adaloglou, M Osterland, FM Morelli, M Halawa, T König, D Gnutt, ...
bioRxiv, 2023.04. 28.538691, 2023
Superoxide Dismutase 1 Folding Stability as a Target for Molecular Tweezers in SOD1‐Related Amyotrophic Lateral Sclerosis
N Samanta, YB Ruiz‐Blanco, Z Fetahaj, D Gnutt, C Lantz, JA Loo, ...
ChemBioChem 23 (21), e202200396, 2022
Cellular ATP levels determine the stability of a nucleotide kinase
O Brylski, P Shrestha, P Gnutt, D Gnutt, JW Mueller, S Ebbinghaus
Frontiers in Molecular Biosciences 8, 790304, 2021
Cryo-EM structural studies of the agonist complexed human TRPV4 ion-channel reveals novel structural rearrangements resulting in an open-conformation. bioRxiv: 2020.2010. 2013 …
M Botte, AKC Ulrich, R Adaixo, D Gnutt, A Brockmann, D Bucher, ...
SOD1 Folding Modulation in the Crowded Cell
D Gnutt, J Ahlers, B König, M Heyden, S Ebbinghaus
Biophysical Journal 114 (3), 52a-53a, 2018
Intracellular spatially-targeted chemical chaperones increase native state stability of mutant SOD1 barrel
SS Ribeiro, D Gnutt, S Azoulay-Ginsburg, Z Fetahaj, E Spurlock, ...
Biological Chemistry 404 (10), 909-930, 2023
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