Frances Northington
Frances Northington
Professor of Pediatrics, Johns Hopkins University
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A systematic review of the role of intrapartum hypoxia-ischemia in the causation of neonatal encephalopathy
EM Graham, KA Ruis, AL Hartman, FJ Northington, HE Fox
American journal of obstetrics and gynecology 199 (6), 587-595, 2008
Neuronal cell death in neonatal hypoxia‐ischemia
FJ Northington, R Chavez‐Valdez, LJ Martin
Annals of neurology 69 (5), 743-758, 2011
Early neurodegeneration after hypoxia-ischemia in neonatal rat is necrosis while delayed neuronal death is apoptosis
FJ Northington, DM Ferriero, EM Graham, RJ Traystman, LJ Martin
Neurobiology of disease 8 (2), 207-219, 2001
Treatment advances in neonatal neuroprotection and neurointensive care
MV Johnston, A Fatemi, MA Wilson, F Northington
The Lancet Neurology 10 (4), 372-382, 2011
Delayed neurodegeneration in neonatal rat thalamus after hypoxia–ischemia is apoptosis
FJ Northington, DM Ferriero, DL Flock, LJ Martin
Journal of Neuroscience 21 (6), 1931-1938, 2001
PARP‐1 gene disruption in mice preferentially protects males from perinatal brain injury
H Hagberg, MA Wilson, H Matsushita, C Zhu, M Lange, M Gustavsson, ...
Journal of neurochemistry 90 (5), 1068-1075, 2004
Necrostatin decreases oxidative damage, inflammation, and injury after neonatal HI
FJ Northington, R Chavez-Valdez, EM Graham, S Razdan, EB Gauda, ...
Journal of Cerebral Blood Flow & Metabolism 31 (1), 178-189, 2011
Increased morbidity in severe early intrauterine growth restriction
SW Aucott, PK Donohue, FJ Northington
Journal of perinatology 24 (7), 435-440, 2004
Which neuroprotective agents are ready for bench to bedside translation in the newborn infant?
NJ Robertson, S Tan, F Groenendaal, F Van Bel, SE Juul, L Bennet, ...
The Journal of pediatrics 160 (4), 544-552. e4, 2012
Cell therapy for neonatal hypoxia–ischemia and cerebral palsy
L Bennet, S Tan, L Van den Heuij, M Derrick, F Groenendaal, F Van Bel, ...
Annals of neurology 71 (5), 589-600, 2012
Glial fibrillary acidic protein as a biomarker for neonatal hypoxic-ischemic encephalopathy treated with whole-body cooling
CS Ennen, TAGM Huisman, WJ Savage, FJ Northington, JM Jennings, ...
American journal of obstetrics and gynecology 205 (3), 251. e1-251. e7, 2011
Failure to complete apoptosis following neonatal hypoxia–ischemia manifests as “continuum” phenotype of cell death and occurs with multiple manifestations of mitochondrial …
FJ Northington, ME Zelaya, DP O’Riordan, K Blomgren, DL Flock, ...
Neuroscience 149 (4), 822-833, 2007
Apoptosis in perinatal hypoxic–ischemic brain injury: how important is it and should it be inhibited?
FJ Northington, EM Graham, LJ Martin
Brain research reviews 50 (2), 244-257, 2005
Brief update on animal models of hypoxic-ischemic encephalopathy and neonatal stroke
FJ Northington
ILAR journal 47 (1), 32-38, 2006
Competitive inhibition of nitric oxide synthase prevents the cortical hyperemia associated with peripheral nerve stimulation
FJ Northington, GP Matherne, RM Berne
Proceedings of the National Academy of Sciences 89 (14), 6649-6652, 1992
Cerebrovascular autoregulation and neurologic injury in neonatal hypoxic–ischemic encephalopathy
JA Howlett, FJ Northington, MM Gilmore, A Tekes, TAGM Huisman, ...
Pediatric research 74 (5), 525-535, 2013
Neonatal mice lacking functional Fas death receptors are resistant to hypoxic–ischemic brain injury
EM Graham, RA Sheldon, DL Flock, DM Ferriero, LJ Martin, DP O'Riordan, ...
Neurobiology of disease 17 (1), 89-98, 2004
Necrostatin-1 attenuates mitochondrial dysfunction in neurons and astrocytes following neonatal hypoxia–ischemia
R Chavez-Valdez, LJ Martin, DL Flock, FJ Northington
Neuroscience 219, 192-203, 2012
Reduction of caspase-8 and-9 cleavage is associated with increased c-FLIP and increased binding of Apaf-1 and Hsp70 after neonatal hypoxic/ischemic injury in mice …
Y Matsumori, FJ Northington, SM Hong, T Kayama, RA Sheldon, ...
Stroke 37 (2), 507-512, 2006
Neurodegeneration in the thalamus following neonatal hypoxia-ischemia is programmed cell death
FJ Northington, DM Ferriero, LJ Martin
Developmental neuroscience 23 (3), 186-191, 2001
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