Oxidative stress and calcium dysregulation by palmitate in type 2 diabetes LD Ly, S Xu, SK Choi, CM Ha, T Thoudam, SK Cha, A Wiederkehr, ... Experimental & molecular medicine 49 (2), e291-e291, 2017 | 335 | 2017 |
Split-TurboID enables contact-dependent proximity labeling in cells KF Cho, TC Branon, S Rajeev, T Svinkina, ND Udeshi, T Thoudam, ... Proceedings of the National Academy of Sciences 117 (22), 12143-12154, 2020 | 216 | 2020 |
Role of the pyruvate dehydrogenase complex in metabolic remodeling: differential pyruvate dehydrogenase complex functions in metabolism S Park, JH Jeon, BK Min, CM Ha, T Thoudam, BY Park, IK Lee Diabetes & metabolism journal 42 (4), 270, 2018 | 151 | 2018 |
PDK4 augments ER–mitochondria contact to dampen skeletal muscle insulin signaling during obesity T Thoudam, CM Ha, J Leem, D Chanda, JS Park, HJ Kim, JH Jeon, ... Diabetes 68 (3), 571-586, 2019 | 127 | 2019 |
Low-dose persistent organic pollutants impair insulin secretory function of pancreatic β-cells: human and in vitro evidence YM Lee, CM Ha, SA Kim, T Thoudam, YR Yoon, DJ Kim, HC Kim, ... Diabetes 66 (10), 2669-2680, 2017 | 73 | 2017 |
Role of mitochondria-associated endoplasmic reticulum membrane in inflammation-mediated metabolic diseases T Thoudam, JH Jeon, CM Ha, IK Lee Mediators of inflammation 2016, 2016 | 70 | 2016 |
Serum metabolomic profiling identifies key metabolic signatures associated with pathogenesis of alcoholic liver disease in humans Z Yang, P Kusumanchi, RA Ross, L Heathers, K Chandler, A Oshodi, ... Hepatology Communications 3 (4), 542-557, 2019 | 46 | 2019 |
Loss of metabolic flexibility as a result of overexpression of pyruvate dehydrogenase kinases in muscle, liver and the immune system: Therapeutic targets in metabolic diseases JH Jeon, T Thoudam, EJ Choi, MJ Kim, RA Harris, IK Lee Journal of Diabetes Investigation 12 (1), 21-31, 2021 | 37 | 2021 |
The role of pyruvate metabolism in mitochondrial quality control and inflammation MJ Kim, H Lee, D Chanda, T Thoudam, HJ Kang, RA Harris, IK Lee Molecules and cells 46 (5), 259-267, 2023 | 16 | 2023 |
Noncanonical PDK4 action alters mitochondrial dynamics to affect the cellular respiratory status T Thoudam, D Chanda, IS Sinam, BG Kim, MJ Kim, CJ Oh, JY Lee, ... Proceedings of the National Academy of Sciences 119 (34), e2120157119, 2022 | 16 | 2022 |
Inhibition of pyruvate dehydrogenase kinase 4 in CD4+ T cells ameliorates intestinal inflammation H Lee, JH Jeon, YJ Lee, MJ Kim, WH Kwon, D Chanda, T Thoudam, ... Cellular and Molecular Gastroenterology and Hepatology 15 (2), 439-461, 2023 | 13 | 2023 |
Enhanced Ca2+-channeling complex formation at the ER-mitochondria interface underlies the pathogenesis of alcohol-associated liver disease T Thoudam, D Chanda, JY Lee, MK Jung, IS Sinam, BG Kim, BY Park, ... Nature communications 14 (1), 1703, 2023 | 10 | 2023 |
Pyruvate dehydrogenase kinase 4 promotes ubiquitin–proteasome system‐dependent muscle atrophy IS Sinam, D Chanda, T Thoudam, MJ Kim, BG Kim, HJ Kang, JY Lee, ... Journal of Cachexia, Sarcopenia and Muscle 13 (6), 3122-3136, 2022 | 9 | 2022 |
Inhibition of pyruvate dehydrogenase kinase 4 ameliorates kidney ischemia-reperfusion injury by reducing succinate accumulation during ischemia and preserving mitochondrial … CJ Oh, MJ Kim, JM Lee, DH Kim, IY Kim, S Park, Y Kim, KB Lee, SH Lee, ... Kidney International 104 (4), 724-739, 2023 | 8 | 2023 |
ApoE4-dependent lysosomal cholesterol accumulation impairs mitochondrial homeostasis and oxidative phosphorylation in human astrocytes H Lee, S Cho, MJ Kim, YJ Park, E Cho, YS Jo, YS Kim, JY Lee, ... Cell Reports 42 (10), 2023 | 5 | 2023 |
Upregulation of the ERRγ–VDAC1 axis underlies the molecular pathogenesis of pancreatitis D Chanda, T Thoudam, IS Sinam, CW Lim, M Kim, J Wang, KM Lee, J Ma, ... Proceedings of the National Academy of Sciences 120 (20), e2219644120, 2023 | 3 | 2023 |
Gossypetin prevents the progression of nonalcoholic steatohepatitis by regulating oxidative stress and AMP-activated protein kinase E Oh, J Lee, S Cho, SW Kim, K Won, WS Shin, SH Gwak, J Ha, SY Jeon, ... Molecular Pharmacology 104 (5), 214-229, 2023 | 1 | 2023 |
Mo1507 GUT-DERIVED MIR-21-ENRICHED EXTRACELLULAR VESICLES DRIVE THE PATHOGENESIS OF ALCOHOL-ASSOCIATED HEPATITIS THROUGH SUPPRESSION OF THE TIMP3-TACE-TNFα PATHWAY IN HEPATOCYTES J Ma, T Zhang, T Thoudam, H Gao, N Huda, Y Jiang, Z Yang, ... Gastroenterology 166 (5), S-1672, 2024 | | 2024 |
Inhibitory regulation of FoxO1 in PPARδ expression drives mitochondria dysfunction and insulin resistance S Park, HN Cha, MG Shin, S Park, Y Kim, MS Kim, KH Shin, T Thoudam, ... Diabetes, db230432, 2024 | | 2024 |
PDK4 is required for MAM formation associated with palmitate induced insulin resistance in C2C12 cells T Thoudam, J Jeon, D Chanda, J Lee International Congress of Diabetes and Metabolism 2018, 140-140, 2018 | | 2018 |