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Zach Herbert
Zach Herbert
Lead Scientist, Dana-Farber Cancer Institute
mail.dfci.harvard.edu의 이메일 확인됨
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Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
AA Chakraborty, T Laukka, M Myllykoski, AE Ringel, MA Booker, ...
Science 363 (6432), 1217-1222, 2019
3452019
The public repository of xenografts enables discovery and randomized phase II-like trials in mice
EC Townsend, MA Murakami, A Christodoulou, AL Christie, J Köster, ...
Cancer cell 29 (4), 574-586, 2016
3282016
The association between germline BRCA2 variants and sensitivity to platinum‐based chemotherapy among men with metastatic prostate cancer
MM Pomerantz, S Spisák, L Jia, AM Cronin, I Csabai, E Ledet, AO Sartor, ...
Cancer 123 (18), 3532-3539, 2017
2792017
Dynamic reorganization of chromatin accessibility signatures during dedifferentiation of secretory precursors into Lgr5+ intestinal stem cells
U Jadhav, M Saxena, NK O’Neill, A Saadatpour, GC Yuan, Z Herbert, ...
Cell stem cell 21 (1), 65-77. e5, 2017
2362017
3D microfluidic ex vivo culture of organotypic tumor spheroids to model immune checkpoint blockade
AR Aref, M Campisi, E Ivanova, A Portell, D Larios, BP Piel, N Mathur, ...
Lab on a Chip 18 (20), 3129-3143, 2018
2142018
VIPER: Visualization Pipeline for RNA-seq, a Snakemake workflow for efficient and complete RNA-seq analysis
MI Cornwell, M Vangala, L Taing, Z Herbert, J Köster, B Li, H Sun, T Li, ...
BMC bioinformatics 19, 1-14, 2018
1692018
IL-1β inflammatory response driven by primary breast cancer prevents metastasis-initiating cell colonization
Z Castano, BP San Juan, A Spiegel, A Pant, MJ DeCristo, T Laszewski, ...
Nature cell biology 20 (9), 1084-1097, 2018
1452018
IL1R1 is required for celastrol’s leptin-sensitization and antiobesity effects
X Feng, D Guan, T Auen, JW Choi, MA Salazar Hernández, J Lee, ...
Nature medicine 25 (4), 575-582, 2019
962019
Characterization of the neuroendocrine tumor immune microenvironment
A Da Silva, M Bowden, S Zhang, Y Masugi, AR Thorner, ZT Herbert, ...
Pancreas 47 (9), 1123-1129, 2018
832018
Performance assessment of DNA sequencing platforms in the ABRF Next-Generation Sequencing Study
J Foox, SW Tighe, CM Nicolet, JM Zook, M Byrska-Bishop, WE Clarke, ...
Nature biotechnology 39 (9), 1129-1140, 2021
802021
The KDM5A/RBP2 histone demethylase represses NOTCH signaling to sustain neuroendocrine differentiation and promote small cell lung cancer tumorigenesis
MG Oser, AH Sabet, W Gao, AA Chakraborty, AC Schinzel, RB Jennings, ...
Genes & development 33 (23-24), 1718-1738, 2019
802019
Extensive recovery of embryonic enhancer and gene memory stored in hypomethylated enhancer DNA
U Jadhav, A Cavazza, KK Banerjee, H Xie, NK O’Neill, V Saenz-Vash, ...
Molecular cell 74 (3), 542-554. e5, 2019
772019
Impairment of gamma-glutamyl transferase 1 activity in the metabolic pathogenesis of chromophobe renal cell carcinoma
C Priolo, D Khabibullin, E Reznik, H Filippakis, B Ogórek, TR Kavanagh, ...
Proceedings of the National Academy of Sciences 115 (27), E6274-E6282, 2018
702018
Systemic lupus erythematosus favors the generation of IL-17 producing double negative T cells
H Li, IE Adamopoulos, VR Moulton, IE Stillman, Z Herbert, JJ Moon, ...
Nature communications 11 (1), 2859, 2020
692020
Cross-site comparison of ribosomal depletion kits for Illumina RNAseq library construction
ZT Herbert, JP Kershner, VL Butty, J Thimmapuram, S Choudhari, ...
BMC genomics 19, 1-10, 2018
592018
Mitogenic and progenitor gene programmes in single pilocytic astrocytoma cells
ZJ Reitman, BR Paolella, G Bergthold, K Pelton, S Becker, R Jones, ...
Nature communications 10 (1), 3731, 2019
552019
Basal-A triple-negative breast cancer cells selectively rely on RNA splicing for survival
S Chan, P Sridhar, R Kirchner, YJ Lock, Z Herbert, S Buonamici, P Smith, ...
Molecular cancer therapeutics 16 (12), 2849-2861, 2017
412017
Astrocyte-neuron crosstalk through Hedgehog signaling mediates cortical synapse development
Y Xie, AT Kuan, W Wang, ZT Herbert, O Mosto, O Olukoya, M Adam, S Vu, ...
Cell reports 38 (8), 2022
372022
Multiomic analysis identifies CPT1A as a potential therapeutic target in platinum-refractory, high-grade serous ovarian cancer
D Huang, S Chowdhury, H Wang, SR Savage, RG Ivey, JJ Kennedy, ...
Cell Reports Medicine 2 (12), 2021
322021
Targeting phospholipase D4 attenuates kidney fibrosis
P Trivedi, RK Kumar, A Iyer, S Boswell, C Gerarduzzi, VP Dadhania, ...
Journal of the American Society of Nephrology 28 (12), 3579-3589, 2017
192017
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