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Jung Min Han
Jung Min Han
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Leucyl-tRNA synthetase is an intracellular leucine sensor for the mTORC1-signaling pathway
JM Han, SJ Jeong, MC Park, G Kim, NH Kwon, HK Kim, SH Ha, SH Ryu, ...
Cell 149 (2), 410-424, 2012
8892012
Glutamine reliance in cell metabolism
HC Yoo, YC Yu, Y Sung, JM Han
Experimental & molecular medicine 52 (9), 1496-1516, 2020
7192020
A variant of SLC1A5 is a mitochondrial glutamine transporter for metabolic reprogramming in cancer cells
HC Yoo, SJ Park, M Nam, J Kang, K Kim, JH Yeo, JK Kim, Y Heo, HS Lee, ...
Cell metabolism 31 (2), 267-283. e12, 2020
3522020
Somatic mutations in TSC1 and TSC2 cause focal cortical dysplasia
JS Lim, R Gopalappa, SH Kim, S Ramakrishna, M Lee, W Kim, J Kim, ...
The American Journal of Human Genetics 100 (3), 454-472, 2017
2132017
Downregulation of FUSE-binding protein and c-myc by tRNA synthetase cofactor p38 is required for lung cell differentiation
MJ Kim, BJ Park, YS Kang, HJ Kim, JH Park, JW Kang, SW Lee, JM Han, ...
Nature genetics 34 (3), 330-336, 2003
2132003
LysRS serves as a key signaling molecule in the immune response by regulating gene expression
N Yannay-Cohen, I Carmi-Levy, G Kay, CM Yang, JM Han, DM Kemeny, ...
Molecular cell 34 (5), 603-611, 2009
1822009
Secreted human glycyl-tRNA synthetase implicated in defense against ERK-activated tumorigenesis
MC Park, T Kang, D Jin, JM Han, SB Kim, YJ Park, K Cho, YW Park, ...
Proceedings of the National Academy of Sciences 109 (11), E640-E647, 2012
1692012
Dual role of methionyl-tRNA synthetase in the regulation of translation and tumor suppressor activity of aminoacyl-tRNA synthetase-interacting multifunctional protein-3
NH Kwon, T Kang, JY Lee, HH Kim, HR Kim, J Hong, YS Oh, JM Han, ...
Proceedings of the National Academy of Sciences 108 (49), 19635-19640, 2011
1392011
AIMP2/p38, the scaffold for the multi-tRNA synthetase complex, responds to genotoxic stresses via p53
JM Han, BJ Park, SG Park, YS Oh, SJ Choi, SW Lee, SK Hwang, ...
Proceedings of the National Academy of Sciences 105 (32), 11206-11211, 2008
1382008
Activation of phospholipase D1 by direct interaction with ADP-ribosylation factor 1 and RalA
JH Kim, S Do Lee, JM Han, TG Lee, Y Kim, JB Park, JD Lambeth, PG Suh, ...
FEBS letters 430 (3), 231-235, 1998
1381998
Cancer-associated splicing variant of tumor suppressor AIMP2/p38: pathological implication in tumorigenesis
JW Choi, DG Kim, AE Lee, HR Kim, JY Lee, NH Kwon, YK Shin, ...
PLoS genetics 7 (3), e1001351, 2011
1202011
Dual requirement for rho and protein kinase C in direct activation of phospholipase D1 through G protein-coupled receptor signaling
G Du, YM Altshuller, Y Kim, JM Han, SH Ryu, AJ Morris, MA Frohman
Molecular biology of the cell 11 (12), 4359-4368, 2000
1132000
Phospholipase D1 is phosphorylated and activated by protein kinase C in caveolin-enriched microdomains within the plasma membrane
Y Kim, JM Han, BR Han, KA Lee, JH Kim, BD Lee, IH Jang, PG Suh, ...
Journal of Biological Chemistry 275 (18), 13621-13627, 2000
1032000
Phosphorylation and activation of phospholipase D1 by protein kinase C in vivo: determination of multiple phosphorylation sites
Y Kim, JM Han, JB Park, SD Lee, YS Oh, C Chung, TG Lee, JH Kim, ...
Biochemistry 38 (32), 10344-10351, 1999
961999
Control of leucine-dependent mTORC1 pathway through chemical intervention of leucyl-tRNA synthetase and RagD interaction
JH Kim, C Lee, M Lee, H Wang, K Kim, SJ Park, I Yoon, J Jang, H Zhao, ...
Nature communications 8 (1), 732, 2017
912017
Leucyl-tRNA synthetase activates Vps34 in amino acid-sensing mTORC1 signaling
MS Yoon, K Son, E Arauz, JM Han, S Kim, J Chen
Cell reports 16 (6), 1510-1517, 2016
912016
Hierarchical network between the components of the multi-tRNA synthetase complex: implications for complex formation
JM Han, MJ Lee, SG Park, SH Lee, E Razin, EC Choi, S Kim
Journal of Biological Chemistry 281 (50), 38663-38667, 2006
912006
Coordination of the leucine-sensing Rag GTPase cycle by leucyl-tRNA synthetase in the mTORC1 signaling pathway
M Lee, JH Kim, I Yoon, C Lee, M Fallahi Sichani, JS Kang, J Kang, M Guo, ...
Proceedings of the National Academy of Sciences 115 (23), E5279-E5288, 2018
902018
Glucose-dependent control of leucine metabolism by leucyl-tRNA synthetase 1
I Yoon, M Nam, HK Kim, HS Moon, S Kim, J Jang, JA Song, SJ Jeong, ...
Science 367 (6474), 205-210, 2020
852020
AIMP2 promotes TNF¥á-dependent apoptosis via ubiquitin-mediated degradation of TRAF2
JW Choi, DG Kim, MC Park, JY Um, JM Han, SG Park, EC Choi, S Kim
Journal of cell science 122 (15), 2710-2715, 2009
852009
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