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Che Yang
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De novo protein design enables the precise induction of RSV-neutralizing antibodies
F Sesterhenn, C Yang, J Bonet, JT Cramer, X Wen, Y Wang, CI Chiang, ...
Science 368 (6492), eaay5051, 2020
1482020
Bottom-up de novo design of functional proteins with complex structural features
C Yang, F Sesterhenn, J Bonet, EA van Aalen, L Scheller, LA Abriata, ...
Nature Chemical Biology 17 (4), 492-500, 2021
822021
Rosetta FunFolDes–A general framework for the computational design of functional proteins
J Bonet, S Wehrle, K Schriever, C Yang, A Billet, F Sesterhenn, A Scheck, ...
PLoS computational biology 14 (11), e1006623, 2018
382018
Boosting subdominant neutralizing antibody responses with a computationally designed epitope-focused immunogen
F Sesterhenn, M Galloux, SS Vollers, L Csepregi, C Yang, D Descamps, ...
PLoS biology 17 (2), e3000164, 2019
352019
A rational blueprint for the design of chemically-controlled protein switches
S Shui, P Gainza, L Scheller, C Yang, Y Kurumida, S Rosset, S Georgeon, ...
Nature Communications 12 (1), 5754, 2021
262021
Assessing and enhancing foldability in designed proteins
D Listov, R Lipsh‐Sokolik, S Rosset, C Yang, BE Correia, SJ Fleishman
Protein Science 31 (9), e4400, 2022
142022
Revealing structural changes of prion protein during conversion from α-helical monomer to β-oligomers by means of ESR and nanochannel encapsulation
C Yang, WL Lo, YH Kuo, JC Sang, CY Lee, YW Chiang, RPY Chen
ACS Chemical Biology 10 (2), 493-501, 2015
122015
A generic framework for hierarchical de novo protein design
Z Harteveld, J Bonet, S Rosset, C Yang, F Sesterhenn, BE Correia
Proceedings of the National Academy of Sciences 119 (43), e2206111119, 2022
102022
De novo protein design enables precise induction of functional antibodies in vivo
F Sesterhenn, C Yang, J Bonet, JT Cramer, X Wen, Y Wang, CI Chiang, ...
bioRxiv, 685867, 2019
52019
A bottom-up approach for the de novo design of functional proteins
C Yang, F Sesterhenn, J Bonet, E van Aalen, L Scheller, LA Abriata, ...
bioRxiv, 2020.03. 11.988071, 2020
22020
Epitope mapping and fine specificity of human T and B cell responses for novel candidate blood-stage malaria vaccine P27A
KM Geiger, D Guignard, C Yang, JP Bikorimana, BE Correia, S Houard, ...
Frontiers in immunology 11, 517131, 2020
22020
Immunogen
B Correia, F Sesterhenn, C Yang, J Bonet
US Patent App. 17/622,468, 2022
2022
Computational design of bioactive protein switches with multi-logics for cell-based therapeutics
S Shui, P Gainza, L Scheller, C Yang, B Correia
Protein Science 30, 37-37, 2021
2021
Immunogen
B Correia, F Sesterhenn, C Yang, J Bonet
2020
Driving immune responses with synthetic proteins-development of de novo designed immunogens to elicit respiratory syncytial virus neutralizing antibodies
F Sesterhenn, C Yang, J Bonet, M Galloux, X Wen, JT Cramer, ...
32nd Annual Symposium of the Protein-Society 27, 2, 2018
2018
LPDI
J Bonet Martinez, SM Buckley, KM Castro Gilabert, RM Chassot, ...
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