Riekelt Houtkooper
Riekelt Houtkooper
Professor of Translational Metabolism, Academic Medical Center (AMC), Amsterdam
Verified email at amc.nl
Cited by
Cited by
Sirtuins as regulators of metabolism and healthspan
RH Houtkooper, E Pirinen, J Auwerx
Nature reviews Molecular cell biology 13 (4), 225-238, 2012
Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans
S Timmers, E Konings, L Bilet, RH Houtkooper, T van de Weijer, ...
Cell metabolism 14 (5), 612-622, 2011
The NAD+ precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity
C Cantů, RH Houtkooper, E Pirinen, DY Youn, MH Oosterveer, Y Cen, ...
Cell metabolism 15 (6), 838-847, 2012
The NAD+/sirtuin pathway modulates longevity through activation of mitochondrial UPR and FOXO signaling
L Mouchiroud, RH Houtkooper, N Moullan, E Katsyuba, D Ryu, C Cantů, ...
Cell 154 (2), 430-441, 2013
Mitonuclear protein imbalance as a conserved longevity mechanism
RH Houtkooper, L Mouchiroud, D Ryu, N Moullan, E Katsyuba, G Knott, ...
Nature 497 (7450), 451-457, 2013
The Secret Life of NAD+: An Old Metabolite Controlling New Metabolic Signaling Pathways
RH Houtkooper, C Cantů, RJ Wanders, J Auwerx
Endocrine reviews 31 (2), 194-223, 2010
PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation
P Bai, C Cantů, H Oudart, A BrunyŠnszki, Y Cen, C Thomas, H Yamamoto, ...
Cell metabolism 13 (4), 461-468, 2011
Cardiolipin, the heart of mitochondrial metabolism
RH Houtkooper, FM Vaz
Cellular and Molecular Life Sciences 65 (16), 2493-2506, 2008
The metabolic footprint of aging in mice
RH Houtkooper, C Argmann, SM Houten, C Cantů, EH Jeninga, ...
Scientific reports 1 (1), 1-11, 2011
Tetracyclines disturb mitochondrial function across eukaryotic models: a call for caution in biomedical research
N Moullan, L Mouchiroud, X Wang, D Ryu, EG Williams, A Mottis, ...
Cell reports 10 (10), 1681-1691, 2015
Pharmacological approaches to restore mitochondrial function
PA Andreux, RH Houtkooper, J Auwerx
Nature reviews Drug discovery 12 (6), 465-483, 2013
Imp2 controls oxidative phosphorylation and is crucial for preserving glioblastoma cancer stem cells
M Janiszewska, ML Suvŗ, N Riggi, RH Houtkooper, J Auwerx, ...
Genes & development 26 (17), 1926-1944, 2012
Cardiolipin provides an essential activating platform for caspase-8 on mitochondria
F Gonzalvez, ZT Schug, RH Houtkooper, ED MacKenzie, DG Brooks, ...
The Journal of cell biology 183 (4), 681-696, 2008
Cardiac and skeletal muscle defects in a mouse model of human Barth syndrome
D Acehan, F Vaz, RH Houtkooper, J James, V Moore, C Tokunaga, ...
Journal of biological chemistry 286 (2), 899-908, 2011
Metabolic networks of longevity
RH Houtkooper, RW Williams, J Auwerx
Cell 142 (1), 9-14, 2010
Mutations in LPIN1 cause recurrent acute myoglobinuria in childhood
A Zeharia, A Shaag, RH Houtkooper, T Hindi, P de Lonlay, G Erez, ...
The American Journal of Human Genetics 83 (4), 489-494, 2008
Laminar shear stress inhibits endothelial cell metabolism via KLF2-mediated repression of PFKFB3
A Doddaballapur, KM Michalik, Y Manavski, T Lucas, RH Houtkooper, ...
Arteriosclerosis, thrombosis, and vascular biology 35 (1), 137-145, 2015
Systems genetics of metabolism: the use of the BXD murine reference panel for multiscalar integration of traits
PA Andreux, EG Williams, H Koutnikova, RH Houtkooper, MF Champy, ...
Cell 150 (6), 1287-1299, 2012
Metabolic flexibility as an adaptation to energy resources and requirements in health and disease
RL Smith, MR Soeters, RCI WŁst, RH Houtkooper
Endocrine reviews 39 (4), 489-517, 2018
Cardiolipin and monolysocardiolipin analysis in fibroblasts, lymphocytes, and tissues using high-performance liquid chromatography-mass spectrometry as a diagnostic test for†…
RH Houtkooper, RJ Rodenburg, C Thiels, H Lenthe, F Stet, JE Stone, ...
Analytical biochemistry 387 (2), 230-237, 2009
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