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Irene A. Chen
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Dissecting temporal and spatial control of cytokinesis with a myosin II Inhibitor
AF Straight, A Cheung, J Limouze, I Chen, NJ Westwood, JR Sellers, ...
Science 299 (5613), 1743-1747, 2003
15742003
The emergence of competition between model protocells
IA Chen, RW Roberts, JW Szostak
Science 305 (5689), 1474-1476, 2004
4632004
Spontaneous network formation among cooperative RNA replicators
N Vaidya, ML Manapat, IA Chen, R Xulvi-Brunet, EJ Hayden, N Lehman
Nature 491 (7422), 72-77, 2012
4122012
RNA catalysis in model protocell vesicles
IA Chen, K Salehi-Ashtiani, JW Szostak
Journal of the American Chemical Society 127 (38), 13213-13219, 2005
2892005
A kinetic study of the growth of fatty acid vesicles
IA Chen, JW Szostak
Biophysical journal 87 (2), 988-998, 2004
2782004
From self-assembled vesicles to protocells
IA Chen, P Walde
Cold Spring Harbor perspectives in biology 2 (7), a002170, 2010
2422010
Membrane growth can generate a transmembrane pH gradient in fatty acid vesicles
IA Chen, JW Szostak
Proceedings of the National Academy of Sciences 101 (21), 7965-7970, 2004
1892004
Rapid colorimetric detection of bacterial species through the capture of gold nanoparticles by chimeric phages
H Peng, IA Chen
Acs Nano 13 (2), 1244-1252, 2018
1822018
Comprehensive experimental fitness landscape and evolutionary network for small RNA
JI Jiménez, R Xulvi-Brunet, GW Campbell, R Turk-MacLeod, IA Chen
Proceedings of the National Academy of Sciences 110 (37), 14984-14989, 2013
1572013
The RNA world as a model system to study the origin of life
A Pressman, C Blanco, IA Chen
Current Biology 25 (19), R953-R963, 2015
1532015
Effect of stalling after mismatches on the error catastrophe in nonenzymatic nucleic acid replication
S Rajamani, JK Ichida, T Antal, DA Treco, K Leu, MA Nowak, JW Szostak, ...
Journal of the American Chemical Society 132 (16), 5880-5885, 2010
1222010
Microbial predictors of healing and short-term effect of debridement on the microbiome of chronic wounds
S Verbanic, Y Shen, J Lee, JM Deacon, IA Chen
NPJ biofilms and microbiomes 6 (1), 21, 2020
1002020
Controlled phage therapy by photothermal ablation of specific bacterial species using gold nanorods targeted by chimeric phages
H Peng, RE Borg, LP Dow, BL Pruitt, IA Chen
Proceedings of the National Academy of Sciences 117 (4), 1951-1961, 2020
982020
Inhibition of bacterial conjugation by phage M13 and its protein g3p: quantitative analysis and model
A Lin, J Jimenez, J Derr, P Vera, ML Manapat, KM Esvelt, L Villanueva, ...
PloS one 6 (5), e19991, 2011
982011
The prebiotic evolutionary advantage of transferring genetic information from RNA to DNA
K Leu, B Obermayer, S Rajamani, U Gerland, IA Chen
Nucleic acids research 39 (18), 8135-8147, 2011
922011
A strategically positioned cation is crucial for efficient catalysis by chorismate mutase
P Kast, C Grisostomi, IA Chen, S Li, U Krengel, Y Xue, D Hilvert
Journal of Biological Chemistry 275 (47), 36832-36838, 2000
782000
The emergence of cells during the origin of life
IA Chen
Science 314 (5805), 1558-1559, 2006
702006
Mapping a systematic ribozyme fitness landscape reveals a frustrated evolutionary network for self-aminoacylating RNA
AD Pressman, Z Liu, E Janzen, C Blanco, UF Müller, GF Joyce, ...
Journal of the American Chemical Society 141 (15), 6213-6223, 2019
692019
Cascade of reduced speed and accuracy after errors in enzyme-free copying of nucleic acid sequences
K Leu, E Kervio, B Obermayer, RM Turk-MacLeod, C Yuan, ...
Journal of the American Chemical Society 135 (1), 354-366, 2013
652013
From prelife to life: How chemical kinetics become evolutionary dynamics
IA Chen, MA Nowak
Accounts of chemical research 45 (12), 2088-2096, 2012
632012
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Articles 1–20