Haemolytic activity, cytotoxicity and membrane cell permeabilization of semi-synthetic and natural lupane-and oleanane-type saponins C Gauthier, J Legault, K Girard-Lalancette, V Mshvildadze, A Pichette Bioorganic & Medicinal Chemistry 17 (5), 2002-2008, 2009 | 243 | 2009 |
Glycosidation of lupane-type triterpenoids as potent in vitro cytotoxic agents C Gauthier, J Legault, M Lebrun, P Dufour, A Pichette Bioorganic & Medicinal Chemistry 14 (19), 6713-6725, 2006 | 194 | 2006 |
Synthesis and structure–activity relationship study of cytotoxic germanicane-and lupane-type 3β-O-monodesmosidic saponins starting from betulin D Thibeault, C Gauthier, J Legault, J Bouchard, P Dufour, A Pichette Bioorganic & Medicinal Chemistry 15 (18), 6144-6157, 2007 | 138 | 2007 |
Synthesis and cytotoxicity of bidesmosidic betulin and betulinic acid saponins C Gauthier, J Legault, S Lavoie, S Rondeau, S Tremblay, A Pichette Journal of Natural Products 72 (1), 72-81, 2009 | 114 | 2009 |
Advances in the synthesis and pharmacological activity of lupane-type triterpenoid saponins C Gauthier, J Legault, M Piochon-Gauthier, A Pichette Phytochemistry Reviews 10, 521-544, 2011 | 76 | 2011 |
Anticancer diarylheptanoid glycosides from the inner bark of Betula papyrifera V Mshvildadze, J Legault, S Lavoie, C Gauthier, A Pichette Phytochemistry 68 (20), 2531-2536, 2007 | 67 | 2007 |
Synthesis of betulinic acid acyl glucuronide for application in anticancer prodrug monotherapy C Gauthier, J Legault, S Rondeau, A Pichette Tetrahedron Letters 50 (9), 988-991, 2009 | 62 | 2009 |
Synthesis of two natural betulinic acid saponins containing α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranose and their analogues C Gauthier, J Legault, S Lavoie, S Rondeau, S Tremblay, A Pichette Tetrahedron 64 (30-31), 7386-7399, 2008 | 62 | 2008 |
Synthesis and cytotoxicity evaluation of natural α-bisabolol β-D-fucopyranoside and analogues M Piochon, J Legault, C Gauthier, A Pichette Phytochemistry 70 (2), 228-236, 2009 | 55 | 2009 |
Recent progress in the synthesis of naturally occurring triterpenoid saponins C Gauthier, J Legault, A Pichette Mini-Reviews in Organic Chemistry 6 (4), 321, 2009 | 50 | 2009 |
Chemical composition and anti-herpes simplex virus type 1 (HSV-1) activity of extracts from Cornus canadensis S Lavoie, I Côté, A Pichette, C Gauthier, M Ouellet, F Nagau-Lavoie, ... BMC Complementary and Alternative Medicine 17 (1), 123, 2017 | 48 | 2017 |
Synthesis, cytotoxicity, and haemolytic activity of chacotrioside lupane-type neosaponins and their germanicane-type rearrangement products C Gauthier, J Legault, M Piochon, S Lavoie, S Tremblay, A Pichette Bioorganic & Medicinal Chemistry Letters 19 (8), 2310-2314, 2009 | 47 | 2009 |
Burkholderia pseudomallei capsular polysaccharide recognition by a monoclonal antibody reveals key details toward a biodefense vaccine and diagnostics against melioidosis R Marchetti, MJ Dillon, MN Burtnick, MA Hubbard, M Tamigney Kenfack, ... ACS Chemical Biology, 2015 | 45 | 2015 |
Deciphering minimal antigenic epitopes associated with Burkholderia pseudomallei and Burkholderia mallei lipopolysaccharide O-antigens M Tamigney Kenfack, M Mazur, T Nualnoi, TL Shaffer, A Ngassimou, ... Nature Communications 8 (1), 1-13, 2017 | 39 | 2017 |
Abibalsamins A and B, two new tetraterpenoids from Abies balsamea oleoresin S Lavoie, J Legault, C Gauthier, V Mshvildadze, S Mercier, A Pichette Organic Letters 14 (6), 1504-1507, 2012 | 37 | 2012 |
Synthesis of 1,2-cis-homoiminosugars derived from GlcNAc and GalNAc exploiting a β-amino alcohol skeletal rearrangement Y Blériot, N Auberger, Y Jagadeesh, C Gauthier, G Prencipe, AT Tran, ... Organic Letters 16 (21), 5512-5515, 2014 | 36 | 2014 |
Non-stoichiometric O-acetylation of Shigella flexneri 2a O-specific polysaccharide: synthesis and antigenicity C Gauthier, P Chassagne, FX Theillet, C Guerreiro, F Thouron, F Nato, ... Organic & Biomolecular Chemistry 12 (24), 4218-4232, 2014 | 36 | 2014 |
Modulation of bacterial multicellularity via spatio-specific polysaccharide secretion ST Islam, I Vergara Alvarez, F Saïdi, A Giuseppi, E Vinogradov, G Sharma, ... PLoS Biology 18 (6), e3000728, 2020 | 35 | 2020 |
Polysaccharides from Burkholderia species as targets for vaccine development, immunomodulation and chemical synthesis M Cloutier, K Muru, G Ravicoularamin, C Gauthier Natural Product Reports 35 (12), 1251-1293, 2018 | 31 | 2018 |
Intramolecular aglycon delivery enables the synthesis of 6-deoxy-beta-D-manno-heptosides as fragments of Burkholderia pseudomallei and Burkholderia mallei capsular polysaccharide M Tamigney Kenfack, Y Bleriot, C Gauthier The Journal of Organic Chemistry 79 (10), 4615-4634, 2014 | 31 | 2014 |