Organoid cultures derived from patients with advanced prostate cancer D Gao, I Vela, A Sboner, PJ Iaquinta, WR Karthaus, A Gopalan, ... Cell 159 (1), 176-187, 2014 | 1461 | 2014 |
Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway VS Viswanathan, MJ Ryan, HD Dhruv, S Gill, OM Eichhoff, ... Nature 547 (7664), 453-457, 2017 | 1380 | 2017 |
SOX2 promotes lineage plasticity and antiandrogen resistance in TP53-and RB1-deficient prostate cancer P Mu, Z Zhang, M Benelli, WR Karthaus, E Hoover, CC Chen, ... Science 355 (6320), 84-88, 2017 | 893 | 2017 |
Identification of multipotent luminal progenitor cells in human prostate organoid cultures WR Karthaus, PJ Iaquinta, J Drost, A Gracanin, R Van Boxtel, J Wongvipat, ... Cell 159 (1), 163-175, 2014 | 718 | 2014 |
Organoid culture systems for prostate epithelial and cancer tissue J Drost, WR Karthaus, D Gao, E Driehuis, CL Sawyers, Y Chen, H Clevers Nature protocols 11 (2), 347-358, 2016 | 574 | 2016 |
N-Myc induces an EZH2-mediated transcriptional program driving neuroendocrine prostate cancer E Dardenne, H Beltran, M Benelli, K Gayvert, A Berger, L Puca, J Cyrta, ... Cancer cell 30 (4), 563-577, 2016 | 505 | 2016 |
ETS factors reprogram the androgen receptor cistrome and prime prostate tumorigenesis in response to PTEN loss Y Chen, P Chi, S Rockowitz, PJ Iaquinta, T Shamu, S Shukla, D Gao, ... Nature medicine 19 (8), 1023-1029, 2013 | 319 | 2013 |
Patient derived organoids to model rare prostate cancer phenotypes L Puca, R Bareja, D Prandi, R Shaw, M Benelli, WR Karthaus, J Hess, ... Nature communications 9 (1), 2404, 2018 | 299 | 2018 |
Alternative transcription initiation leads to expression of a novel ALK isoform in cancer T Wiesner, W Lee, AC Obenauf, L Ran, R Murali, QF Zhang, EWP Wong, ... Nature 526 (7573), 453-457, 2015 | 236 | 2015 |
SPOP mutation drives prostate tumorigenesis in vivo through coordinate regulation of PI3K/mTOR and AR signaling M Blattner, D Liu, BD Robinson, D Huang, A Poliakov, D Gao, S Nataraj, ... Cancer cell 31 (3), 436-451, 2017 | 204 | 2017 |
In vitro expansion of primary human hepatocytes with efficient liver repopulation capacity K Zhang, L Zhang, W Liu, X Ma, J Cen, Z Sun, C Wang, S Feng, Z Zhang, ... Cell stem cell 23 (6), 806-819. e4, 2018 | 190 | 2018 |
An embryonic diapause-like adaptation with suppressed Myc activity enables tumor treatment persistence E Dhimolea, R de Matos Simoes, D Kansara, A Al’Khafaji, J Bouyssou, ... Cancer cell 39 (2), 240-256. e11, 2021 | 172 | 2021 |
PTEN deficiency and AMPK activation promote nutrient scavenging and anabolism in prostate cancer cells SM Kim, TT Nguyen, A Ravi, P Kubiniok, BT Finicle, V Jayashankar, ... Cancer discovery 8 (7), 866-883, 2018 | 164 | 2018 |
REUL is a novel E3 ubiquitin ligase and stimulator of retinoic-acid-inducible gene-I D Gao, YK Yang, RP Wang, X Zhou, FC Diao, MD Li, ZH Zhai, ZF Jiang, ... PloS one 4 (6), e5760, 2009 | 149 | 2009 |
Negative feedback regulation of cellular antiviral signaling by RBCK1-mediated degradation of IRF3 M Zhang, Y Tian, RP Wang, D Gao, Y Zhang, FC Diao, DY Chen, ZH Zhai, ... Cell research 18 (11), 1096-1104, 2008 | 146 | 2008 |
Combined inhibition of MAP kinase and KIT signaling synergistically destabilizes ETV1 and suppresses GIST tumor growth L Ran, I Sirota, Z Cao, D Murphy, Y Chen, S Shukla, Y Xie, MC Kaufmann, ... Cancer discovery 5 (3), 304-315, 2015 | 129 | 2015 |
Receptome profiling identifies KREMEN1 and ASGR1 as alternative functional receptors of SARS-CoV-2 Y Gu, J Cao, X Zhang, H Gao, Y Wang, J Wang, J He, X Jiang, J Zhang, ... Cell research 32 (1), 24-37, 2022 | 128 | 2022 |
Arterial Sca1+ vascular stem cells generate de novo smooth muscle for artery repair and regeneration J Tang, H Wang, X Huang, F Li, H Zhu, Y Li, L He, H Zhang, W Pu, K Liu, ... Cell stem cell 26 (1), 81-96. e4, 2020 | 118 | 2020 |
Single-cell transcriptomics identifies a distinct luminal progenitor cell type in distal prostate invagination tips W Guo, L Li, J He, Z Liu, M Han, F Li, X Xia, X Zhang, Y Zhu, YU Wei, Y Li, ... Nature genetics 52 (9), 908-918, 2020 | 95 | 2020 |
Organoid development in cancer genome discovery D Gao, Y Chen Current opinion in genetics & development 30, 42-48, 2015 | 94 | 2015 |