A clinically meaningful metric of immune age derived from high-dimensional longitudinal monitoring A Alpert, Y Pickman, M Leipold, Y Rosenberg-Hasson, X Ji, R Gaujoux, ... Nature medicine 25 (3), 487-495, 2019 | 347 | 2019 |
Single-cell chromatin modification profiling reveals increased epigenetic variations with aging P Cheung, F Vallania, HC Warsinske, M Donato, S Schaffert, SE Chang, ... Cell 173 (6), 1385-1397. e14, 2018 | 303 | 2018 |
Antigen recognition determinants of γδ T cell receptors S Shin, R El-Diwany, S Schaffert, EJ Adams, KC Garcia, P Pereira, ... Science 308 (5719), 252-255, 2005 | 225 | 2005 |
The interplay between Epstein–Barr virus and B lymphocytes: implications for infection, immunity, and disease OL Hatton, A Harris-Arnold, S Schaffert, SM Krams, OM Martinez Immunologic research 58, 268-276, 2014 | 207 | 2014 |
Precise gene deletion and replacement using the CRISPR/Cas9 system in human cells Q Zheng, X Cai, MH Tan, S Schaffert, CP Arnold, X Gong, CZ Chen, ... Biotechniques 57 (3), 115-124, 2014 | 191 | 2014 |
Regulation of immune responses and tolerance: The micro RNA perspective CZ Chen, S Schaffert, R Fragoso, C Loh Immunological reviews 253 (1), 112-128, 2013 | 187 | 2013 |
Leveraging heterogeneity across multiple datasets increases cell-mixture deconvolution accuracy and reduces biological and technical biases F Vallania, A Tam, S Lofgren, S Schaffert, TD Azad, E Bongen, W Haynes, ... Nature communications 9 (1), 4735, 2018 | 141 | 2018 |
Modulating the Strength and Threshold of NOTCH Oncogenic Signals by mir-181a-1/b-1 R Fragoso, T Mao, S Wang, S Schaffert, X Gong, S Yue, R Luong, H Min, ... Public Library of Science 8 (8), e1002855, 2012 | 128 | 2012 |
IL-12 enhances efficacy and shortens enrichment time in cytokine-induced killer cell immunotherapy MW Helms, JA Prescher, YA Cao, S Schaffert, CH Contag Cancer immunology, immunotherapy 59, 1325-1334, 2010 | 95 | 2010 |
MicroRNA programs in normal and aberrant stem and progenitor cells CP Arnold, R Tan, B Zhou, SB Yue, S Schaffert, JR Biggs, R Doyonnas, ... Genome Research 21 (5), 798-810, 2011 | 81 | 2011 |
mir-181a-1/b-1 modulates tolerance through opposing activities in selection and peripheral T cell function SA Schaffert, C Loh, S Wang, CP Arnold, RC Axtell, EW Newell, G Nolan, ... The Journal of Immunology 195 (4), 1470-1479, 2015 | 52 | 2015 |
Repression of CTSG, ELANE and PRTN3-mediated histone H3 proteolytic cleavage promotes monocyte-to-macrophage differentiation P Cheung, S Schaffert, SE Chang, M Dvorak, M Donato, C Macaubas, ... Nature immunology 22 (6), 711-722, 2021 | 44 | 2021 |
Epstein–Barr Virus Modulates Host Cell MicroRNA-194 to Promote IL-10 Production and B Lymphoma Cell Survival A Harris-Arnold, CP Arnold, S Schaffert, O Hatton, SM Krams, ... American Journal of Transplantation 15 (11), 2814-2824, 2015 | 34 | 2015 |
Single-cell epigenetics–chromatin modification atlas unveiled by mass cytometry P Cheung, F Vallania, M Dvorak, SE Chang, S Schaffert, M Donato, ... Clinical Immunology 196, 40-48, 2018 | 33 | 2018 |
Ex vivo drug screening defines novel drug sensitivity patterns for informing personalized therapy in myeloid neoplasms MA Spinner, A Aleshin, MT Santaguida, SA Schaffert, JL Zehnder, ... Blood advances 4 (12), 2768-2778, 2020 | 29 | 2020 |
Programmable antivirals targeting critical conserved viral RNA secondary structures from influenza A virus and SARS-CoV-2 RJ Hagey, M Elazar, EA Pham, S Tian, L Ben-Avi, C Bernardin-Souibgui, ... Nature medicine 28 (9), 1944-1955, 2022 | 17 | 2022 |
Masking of a cathepsin G cleavage site in vivo contributes to the proteolytic resistance of major histocompatibility complex class II molecules T Burster, H Macmillan, T Hou, J Schilling, P Truong, BO Boehm, F Zou, ... Immunology 130 (3), 436-446, 2010 | 17 | 2010 |
Masking of a cathepsin G cleavage site in vivo contributes to the proteolytic resistance of major histocompatibility complex class II molecules T Burster, H Macmillan, T Hou, J Schilling, P Truong, BO Boehm, F Zou, ... Immunology 130 (3), 436-446, 2010 | 17 | 2010 |
Applying mass cytometry to the analysis of lymphoid populations in transplantation SM Krams, S Schaffert, AH Lau, OM Martinez American Journal of Transplantation 17 (8), 1992-1999, 2017 | 14 | 2017 |
Early life immunity in the era of systems biology: understanding development and disease S Schaffert, P Khatri Genome medicine 10, 1-3, 2018 | 12 | 2018 |