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Jaime de Juan-Sanz
Jaime de Juan-Sanz
ICM Paris Brain Institute
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Mapping genomic loci implicates genes and synaptic biology in schizophrenia
V Trubetskoy, AF Pardiñas, T Qi, G Panagiotaropoulou, S Awasthi, ...
Nature 604 (7906), 502-508, 2022
15052022
SynGO: an evidence-based, expert-curated knowledge base for the synapse
F Koopmans, P van Nierop, M Andres-Alonso, A Byrnes, T Cijsouw, ...
Neuron 103 (2), 217-234. e4, 2019
6462019
Mitochondrial fission promotes the continued clearance of apoptotic cells by macrophages
Y Wang, M Subramanian, A Yurdagul, VC Barbosa-Lorenzi, B Cai, ...
cell 171 (2), 331-345. e22, 2017
3102017
INF2-mediated actin polymerization at the ER stimulates mitochondrial calcium uptake, inner membrane constriction, and division
R Chakrabarti, WK Ji, RV Stan, J de Juan Sanz, TA Ryan, HN Higgs
Journal of Cell Biology 217 (1), 251-268, 2018
3082018
Axonal endoplasmic reticulum Ca2+ content controls release probability in CNS nerve terminals
J de Juan-Sanz, GT Holt, ER Schreiter, F de Juan, DS Kim, TA Ryan
Neuron 93 (4), 867-881. e6, 2017
2502017
Molecular tuning of the axonal mitochondrial Ca2+ uniporter ensures metabolic flexibility of neurotransmission
G Ashrafi, J de Juan-Sanz, RJ Farrell, TA Ryan
Neuron 105 (4), 678-687. e5, 2020
1672020
Antimicrobial agent triclosan disrupts mitochondrial structure, revealed by super-resolution microscopy, and inhibits mast cell signaling via calcium modulation
LM Weatherly, AJ Nelson, J Shim, AM Riitano, ED Gerson, AJ Hart, ...
Toxicology and applied pharmacology 349, 39-54, 2018
542018
Na+/K+-ATPase is a new interacting partner for the neuronal glycine transporter GlyT2 that downregulates its expression in vitro and in vivo
J de Juan-Sanz, E Núñez, L Villarejo-López, D Pérez-Hernández, ...
Journal of Neuroscience 33 (35), 14269-14281, 2013
542013
A novel dominant hyperekplexia mutation Y705C alters trafficking and biochemical properties of the presynaptic glycine transporter GlyT2
C Giménez, G Pérez-Siles, J Martínez-Villarreal, E Arribas-González, ...
Journal of Biological Chemistry 287 (34), 28986-29002, 2012
462012
Endocytosis of the Neuronal Glycine Transporter GLYT2: Role of Membrane Rafts and Protein Kinase C‐Dependent Ubiquitination
J de Juan‐Sanz, F Zafra, B López‐Corcuera, C Aragón
Traffic 12 (12), 1850-1867, 2011
442011
Molecular basis of the dominant negative effect of a glycine transporter 2 mutation associated with hyperekplexia
E Arribas-González, J de Juan-Sanz, C Aragón, B López-Corcuera
Journal of Biological Chemistry 290 (4), 2150-2165, 2015
362015
Constitutive endocytosis and turnover of the neuronal glycine transporter GlyT2 is dependent on ubiquitination of a C-terminal lysine cluster
J de Juan-Sanz, E Núñez, B López-Corcuera, C Aragón
PLoS One 8 (3), e58863, 2013
322013
Presynaptic control of glycine transporter 2 (GlyT2) by physical and functional association with plasma membrane Ca2+-ATPase (PMCA) and Na+-Ca2+ exchanger (NCX)
J de Juan-Sanz, E Núñez, F Zafra, M Berrocal, I Corbacho, I Ibáñez, ...
Journal Of Biological Chemistry 289 (49), 34308-34324, 2014
312014
E3 ubiquitin ligases LNX1 and LNX2 are major regulators of the presynaptic glycine transporter GlyT2
A de La Rocha-Muñoz, E Núñez, E Arribas-González, B López-Corcuera, ...
Scientific Reports 9 (1), 14944, 2019
152019
Sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) activity is required for V(D)J recombination
CC Chen, BR Chen, Y Wang, P Curman, HA Beilinson, RM Brecht, ...
Journal of Experimental Medicine 218 (8), e20201708, 2021
132021
STIM1 deficiency leads to specific down-regulation of ITPR3 in SH-SY5Y cells
C Pascual-Caro, Y Orantos-Aguilera, I Sanchez-Lopez, J de Juan-Sanz, ...
International Journal of Molecular Sciences 21 (18), 6598, 2020
122020
Activity-driven synaptic translocation of LGI1 controls excitatory neurotransmission
U Cuhadar, L Calzado-Reyes, C Pascual-Caro, AS Aberra, A Ritzau-Jost, ...
Cell Reports 43 (5), 2024
32024
Rational Engineering of an Improved Genetically Encoded pH Sensor Based on Superecliptic pHluorin
Y Shen, Y Wen, S Sposini, AA Vishwanath, AS Abdelfattah, ER Schreiter, ...
ACS sensors 8 (8), 3014-3022, 2023
32023
The presynaptic glycine transporter GlyT2 is regulated by the Hedgehog pathway in vitro and in vivo
A de La Rocha-Muñoz, E Núñez, AA Vishwanath, S Gómez-López, ...
Communications Biology 4 (1), 1197, 2021
32021
Regulation of the glycinergic neurotransmission during inflammatory pain: A new pathway in the action of Prostaglandin E2 in the spinal cord
J de Juan-Sanz, E Nunez, B Lopez-Corcuera, C Aragon
Anal. Real Acad. Nal. Farm. 79 (3), 434-449, 2013
22013
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