Inhibiting macrophage proliferation suppresses atherosclerotic plaque inflammation J Tang, ME Lobatto, L Hassing, S Van Der Staay, SM Van Rijs, ... Science advances 1 (3), e1400223, 2015 | 225 | 2015 |
Inhibiting inflammation with myeloid cell-specific nanobiologics promotes organ transplant acceptance MS Braza, MMT van Leent, M Lameijer, BL Sanchez-Gaytan, RJW Arts, ... Immunity 49 (5), 819-828. e6, 2018 | 195 | 2018 |
PET imaging of tumor-associated macrophages with 89Zr-labeled high-density lipoprotein nanoparticles C Pérez-Medina, J Tang, D Abdel-Atti, B Hogstad, M Merad, EA Fisher, ... Journal of nuclear medicine 56 (8), 1272-1277, 2015 | 175 | 2015 |
Hyaluronan nanoparticles selectively target plaque-associated macrophages and improve plaque stability in atherosclerosis TJ Beldman, ML Senders, A Alaarg, C Pérez-Medina, J Tang, Y Zhao, ... Acs Nano 11 (6), 5785-5799, 2017 | 163 | 2017 |
Investigating supramolecular systems using Förster resonance energy transfer AJP Teunissen, C Pérez-Medina, A Meijerink, WJM Mulder Chemical Society Reviews 47 (18), 7027-7044, 2018 | 135 | 2018 |
Polyglucose nanoparticles with renal elimination and macrophage avidity facilitate PET imaging in ischaemic heart disease EJ Keliher, YX Ye, GR Wojtkiewicz, AD Aguirre, B Tricot, ML Senders, ... Nature communications 8 (1), 14064, 2017 | 132 | 2017 |
Augmenting drug–carrier compatibility improves tumour nanotherapy efficacy Y Zhao, F Fay, S Hak, J Manuel Perez-Aguilar, BL Sanchez-Gaytan, ... Nature communications 7 (1), 11221, 2016 | 128 | 2016 |
Immune cell screening of a nanoparticle library improves atherosclerosis therapy J Tang, S Baxter, A Menon, A Alaarg, BL Sanchez-Gaytan, F Fay, Y Zhao, ... Proceedings of the National Academy of Sciences 113 (44), E6731-E6740, 2016 | 114 | 2016 |
Nanoreporter PET predicts the efficacy of anti-cancer nanotherapy C Pérez-Medina, D Abdel-Atti, J Tang, Y Zhao, ZA Fayad, JS Lewis, ... Nature communications 7 (1), 11838, 2016 | 111 | 2016 |
Efficacy and safety assessment of a TRAF6-targeted nanoimmunotherapy in atherosclerotic mice and non-human primates M Lameijer, T Binderup, MMT Van Leent, ML Senders, F Fay, J Malkus, ... Nature biomedical engineering 2 (5), 279-292, 2018 | 108 | 2018 |
Trained immunity-promoting nanobiologic therapy suppresses tumor growth and potentiates checkpoint inhibition B Priem, MMT van Leent, AJP Teunissen, AM Sofias, VP Mourits, ... Cell 183 (3), 786-801. e19, 2020 | 104 | 2020 |
In vivo PET imaging of HDL in multiple atherosclerosis models C Pérez-Medina, T Binderup, ME Lobatto, J Tang, C Calcagno, L Giesen, ... JACC: Cardiovascular Imaging 9 (8), 950-961, 2016 | 102 | 2016 |
A modular labeling strategy for in vivo PET and near-infrared fluorescence imaging of nanoparticle tumor targeting C Pérez-Medina, D Abdel-Atti, Y Zhang, VA Longo, CP Irwin, T Binderup, ... Journal of Nuclear Medicine 55 (10), 1706-1711, 2014 | 97 | 2014 |
Imaging macrophage and hematopoietic progenitor proliferation in atherosclerosis YX Ye, C Calcagno, T Binderup, G Courties, EJ Keliher, GR Wojtkiewicz, ... Circulation research 117 (10), 835-845, 2015 | 85 | 2015 |
Tumor Targeting by αvβ3-Integrin-Specific Lipid Nanoparticles Occurs via Phagocyte Hitchhiking AM Sofias, YC Toner, AE Meerwaldt, MMT van Leent, G Soultanidis, ... ACS nano 14 (7), 7832-7846, 2020 | 77 | 2020 |
Nanobody-facilitated multiparametric PET/MRI phenotyping of atherosclerosis ML Senders, S Hernot, G Carlucci, JC van de Voort, F Fay, C Calcagno, ... JACC: Cardiovascular Imaging 12 (10), 2015-2026, 2019 | 74 | 2019 |
High-density lipoprotein nanobiologics for precision medicine WJM Mulder, MMT Van Leent, M Lameijer, EA Fisher, ZA Fayad, ... Accounts of chemical research 51 (1), 127-137, 2018 | 68 | 2018 |
Imaging-assisted nanoimmunotherapy for atherosclerosis in multiple species T Binderup, R Duivenvoorden, F Fay, MMT van Leent, J Malkus, S Baxter, ... Science translational medicine 11 (506), eaaw7736, 2019 | 60 | 2019 |
Fluorinated indazoles as novel selective inhibitors of nitric oxide synthase (NOS): Synthesis and biological evaluation RM Claramunt, C Lopez, C Perez-Medina, M Perez-Torralba, J Elguero, ... Bioorganic & medicinal chemistry 17 (17), 6180-6187, 2009 | 57 | 2009 |
A systematic comparison of clinically viable nanomedicines targeting HMG-CoA reductase in inflammatory atherosclerosis A Alaarg, ML Senders, A Varela-Moreira, C Pérez-Medina, Y Zhao, ... Journal of controlled release 262, 47-57, 2017 | 53 | 2017 |