Tau prion strains dictate patterns of cell pathology, progression rate, and regional vulnerability in vivo SK Kaufman, DW Sanders, TL Thomas, AJ Ruchinskas, J Vaquer-Alicea, ... Neuron 92 (4), 796-812, 2016 | 411 | 2016 |
Propagation of protein aggregation in neurodegenerative diseases J Vaquer-Alicea, MI Diamond Annual review of biochemistry 88, 785-810, 2019 | 251 | 2019 |
Specific glycosaminoglycan chain length and sulfation patterns are required for cell uptake of tau versus α-synuclein and β-amyloid aggregates BE Stopschinski, BB Holmes, GM Miller, VA Manon, J Vaquer-Alicea, ... Journal of Biological Chemistry 293 (27), 10826-10840, 2018 | 167 | 2018 |
Widespread tau seeding activity at early Braak stages JL Furman, J Vaquer-Alicea, CL White, NJ Cairns, PT Nelson, ... Acta neuropathologica 133, 91-100, 2017 | 136 | 2017 |
Tau strains shape disease J Vaquer-Alicea, MI Diamond, LA Joachimiak Acta neuropathologica 142 (1), 57-71, 2021 | 99 | 2021 |
EFhd2 is a novel amyloid protein associated with pathological tau in Alzheimer's disease Y Ferrer‐Acosta, EN Rodríguez‐Cruz, F Orange, H Jesús‐Cortés, ... Journal of neurochemistry 125 (6), 921-931, 2013 | 48 | 2013 |
Ultrasensitive tau biosensor cells detect no seeding in Alzheimer’s disease CSF BD Hitt, J Vaquer-Alicea, VA Manon, JD Beaver, OM Kashmer, JN Garcia, ... Acta Neuropathologica Communications 9 (1), 99, 2021 | 38 | 2021 |
Regulatory inter-domain interactions influence Hsp70 recruitment to the DnaJB8 chaperone BD Ryder, I Matlahov, S Bali, J Vaquer-Alicea, PCA van der Wel, ... Nature communications 12 (1), 946, 2021 | 23 | 2021 |
VCP suppresses proteopathic seeding in neurons J Zhu, S Pittman, D Dhavale, R French, JN Patterson, ... Molecular neurodegeneration 17 (1), 30, 2022 | 16 | 2022 |
Network of hotspot interactions cluster tau amyloid folds V Mullapudi, J Vaquer-Alicea, V Bommareddy, AR Vega, BD Ryder, ... Nature communications 14 (1), 895, 2023 | 13 | 2023 |
FTD-tau S320F mutation stabilizes local structure and allosterically promotes amyloid motif-dependent aggregation D Chen, S Bali, R Singh, A Wosztyl, V Mullapudi, J Vaquer-Alicea, ... Nature communications 14 (1), 1625, 2023 | 7 | 2023 |
Novel autoimmune response in a tauopathy mouse model CJ Nogueras-Ortiz, HJ De Jesús-Cortes, J Vaquer-Alicea, IE Vega Frontiers in neuroscience 7, 277, 2014 | 6 | 2014 |
Cryo-EM structure of Alzheimer’s disease tau filaments with PET ligand MK-6240 P Kunach, J Vaquer-Alicea, MS Smith, R Hopewell, J Monistrol, L Moquin, ... bioRxiv, 2023 | 3 | 2023 |
VCP increases or decreases tau seeding using specific cofactors S Batra, J Vaquer-Alicea III, VA Manon, OM Kashmer, A Lemoff, NJ Cairns, ... bioRxiv, 2023 | 2 | 2023 |
Abstract 2445 Elucidating Tau Fibril Formation using Correlative Cryo-CLEM in situ S Shahmoradian, J Monistrol, HT Tran, V Perez, J Jiou, J Vaquer-Alicea, ... Journal of Biological Chemistry 300 (3), 2024 | | 2024 |
Tau biosensor cell lines M Diamond, V Manon, J Vaquer-alicea, H Brian US Patent App. 18/266,712, 2024 | | 2024 |
ATTRv-V30M Type A amyloid fibrils from the heart and nerves exhibit structural homogeneity. BA Nguyen, S Afrin, A Yakubovska, V Singh, J Vaquer-Alicea, P Kunach, ... bioRxiv, 2024.05. 14.594028, 2024 | | 2024 |
Tdp-43 biosensor cell lines MI Diamond, J Vaquer-alicea, GC Maggiore US Patent App. 18/014,850, 2023 | | 2023 |
Cryo-EM structure determination of sub nanomolar affinity PET ligand, MK-6240, bound to Alzheimer’s Disease Paired Helical Filament P Kunach, J Vaquer-Alicea, J Monistrol, J Therriault, C Tissot, R Hopewell, ... Alzheimer's Association International Conference, 2023 | | 2023 |
Tau peptide antigens and antibodies binding thereto for the treatment of tauopathies MI Diamond, K Drombosky, C Dailu, V Manon, X Liu, H Mirzaei, ... US Patent App. 17/295,152, 2022 | | 2022 |