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Aik Choon Tan
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Patient-derived tumour xenografts as models for oncology drug development
JJ Tentler, AC Tan, CD Weekes, A Jimeno, S Leong, TM Pitts, JJ Arcaroli, ...
Nature reviews Clinical oncology 9 (6), 338-350, 2012
11972012
Caspase 3–mediated stimulation of tumor cell repopulation during cancer radiotherapy
Q Huang, F Li, X Liu, W Li, W Shi, FF Liu, B O'sullivan, Z He, Y Peng, ...
Nature medicine 17 (7), 860-866, 2011
7472011
Ensemble machine learning on gene expression data for cancer classification
AC Tan, D Gilbert
University of Glasgow, 2003
5042003
Simple decision rules for classifying human cancers from gene expression profiles
AC Tan, DQ Naiman, L Xu, RL Winslow, D Geman
Bioinformatics 21 (20), 3896-3904, 2005
4432005
Optimizing the detection of lung cancer patients harboring anaplastic lymphoma kinase (ALK) gene rearrangements potentially suitable for ALK inhibitor treatment
DR Camidge, SA Kono, A Flacco, AC Tan, RC Doebele, Q Zhou, L Crino, ...
Clinical Cancer Research 16 (22), 5581-5590, 2010
3902010
A DNA methylation fingerprint of 1628 human samples
AF Fernandez, Y Assenov, JI Martin-Subero, B Balint, R Siebert, ...
Genome research 22 (2), 407-419, 2012
3882012
Postpartum mammary gland involution drives progression of ductal carcinoma in situ through collagen and COX-2
TR Lyons, J O'brien, VF Borges, MW Conklin, PJ Keely, KW Eliceiri, ...
Nature medicine 17 (9), 1109-1115, 2011
3492011
The miR-106b-25 cluster targets Smad7, activates TGF-β signaling, and induces EMT and tumor initiating cell characteristics downstream of Six1 in human breast cancer
AL Smith, R Iwanaga, DJ Drasin, DS Micalizzi, RL Vartuli, AC Tan, ...
Oncogene 31 (50), 5162-5171, 2012
3372012
Genetic analysis of 779 advanced differentiated and anaplastic thyroid cancers
N Pozdeyev, LM Gay, ES Sokol, R Hartmaier, KE Deaver, S Davis, ...
Clinical Cancer Research 24 (13), 3059-3068, 2018
2782018
Tumor Engraftment in Nude Mice and Enrichment in Stroma-Related Gene Pathways Predict Poor Survival and Resistance to Gemcitabine in Patients with Pancreatic CancerPersonalized …
I Garrido-Laguna, M Uson, NV Rajeshkumar, AC Tan, E De Oliveira, ...
Clinical Cancer Research 17 (17), 5793-5800, 2011
2302011
A mechanism of resistance to gefitinib mediated by cellular reprogramming and the acquisition of an FGF2-FGFR1 autocrine growth loop
KE Ware, TK Hinz, E Kleczko, KR Singleton, LA Marek, BA Helfrich, ...
Oncogenesis 2 (3), e39-e39, 2013
2252013
Direct reprogramming of human fibroblasts into dopaminergic neuron-like cells
X Liu, F Li, EA Stubblefield, B Blanchard, TL Richards, GA Larson, Y He, ...
Cell research 22 (2), 321-332, 2012
1972012
Plasma-based circulating MicroRNA biomarkers for Parkinson's disease
SK Khoo, D Petillo, UJ Kang, JH Resau, B Berryhill, J Linder, L Forsgren, ...
Journal of Parkinson's disease 2 (4), 321-331, 2012
1862012
DSigDB: drug signatures database for gene set analysis
M Yoo, J Shin, J Kim, KA Ryall, K Lee, S Lee, M Jeon, J Kang, AC Tan
Bioinformatics 31 (18), 3069-3071, 2015
1682015
Characterizing DNA methylation patterns in pancreatic cancer genome
AC Tan, A Jimeno, SH Lin, J Wheelhouse, F Chan, A Solomon, ...
Molecular oncology 3 (5-6), 425-438, 2009
1672009
Robust prostate cancer marker genes emerge from direct integration of inter-study microarray data
L Xu, AC Tan, DQ Naiman, D Geman, RL Winslow
Bioinformatics 21 (20), 3905-3911, 2005
1672005
Multi-class protein fold classification using a new ensemble machine learning approach
AC Tan, D Gilbert, Y Deville
Genome Informatics 14, 206-217, 2003
1662003
FGFR1 mRNA and protein expression, not gene copy number, predict FGFR TKI sensitivity across all lung cancer histologies
MW Wynes, TK Hinz, D Gao, M Martini, LA Marek, KE Ware, MG Edwards, ...
Clinical cancer research 20 (12), 3299-3309, 2014
1522014
A patient tumor transplant model of squamous cell cancer identifies PI3K inhibitors as candidate therapeutics in defined molecular bins
SB Keysar, DP Astling, RT Anderson, BW Vogler, DW Bowles, JJ Morton, ...
Molecular oncology 7 (4), 776-790, 2013
1512013
AMPK/FIS1-mediated mitophagy is required for self-renewal of human AML stem cells
S Pei, M Minhajuddin, B Adane, N Khan, BM Stevens, SC Mack, S Lai, ...
Cell stem cell 23 (1), 86-100. e6, 2018
1492018
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