Bile acids: natural ligands for an orphan nuclear receptor DJ Parks, SG Blanchard, RK Bledsoe, G Chandra, TG Consler, ... Science 284 (5418), 1365-1368, 1999 | 2569 | 1999 |
Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1α null mice J Lin, PH Wu, PT Tarr, KS Lindenberg, J St-Pierre, C Zhang, VK Mootha, ... Cell 119 (1), 121-135, 2004 | 1425 | 2004 |
Cellular and molecular basis of deiodinase-regulated thyroid hormone signaling B Gereben, AM Zavacki, S Ribich, BW Kim, SA Huang, WS Simonides, ... Endocrine reviews 29 (7), 898-938, 2008 | 1002 | 2008 |
Thyroid hormones and skeletal muscle—new insights and potential implications D Salvatore, WS Simonides, M Dentice, AM Zavacki, PR Larsen Nature Reviews Endocrinology 10 (4), 206-214, 2014 | 365 | 2014 |
LXRs regulate the balance between fat storage and oxidation NY Kalaany, KC Gauthier, AM Zavacki, PPA Mammen, T Kitazume, ... Cell metabolism 1 (4), 231-244, 2005 | 354 | 2005 |
Identification of the DNA binding specificity and potential target genes for the farnesoid X-activated receptor BA Laffitte, HR Kast, CM Nguyen, AM Zavacki, DD Moore, PA Edwards Journal of Biological Chemistry 275 (14), 10638-10647, 2000 | 324 | 2000 |
The Hedgehog-inducible ubiquitin ligase subunit WSB-1 modulates thyroid hormone activation and PTHrP secretion in the developing growth plate M Dentice, A Bandyopadhyay, B Gereben, I Callebaut, MA Christoffolete, ... Nature cell biology 7 (7), 698-705, 2005 | 242 | 2005 |
Sonic hedgehog-induced type 3 deiodinase blocks thyroid hormone action enhancing proliferation of normal and malignant keratinocytes M Dentice, C Luongo, S Huang, R Ambrosio, A Elefante, ... Proceedings of the National Academy of Sciences 104 (36), 14466-14471, 2007 | 185 | 2007 |
Paracrine signaling by glial cell–derived triiodothyronine activates neuronal gene expression in the rodent brain and human cells BCG Freitas, B Gereben, M Castillo, I Kalló, A Zeöld, P Egri, Z Liposits, ... The Journal of clinical investigation 120 (6), 2206-2217, 2010 | 184 | 2010 |
A novel retinoid X receptor-independent thyroid hormone response element is present in the human type 1 deiodinase gene N Toyoda, AM Zavacki, AL Maia, JW Harney, PR Larsen Molecular and cellular biology, 1995 | 176 | 1995 |
The deiodinases and the control of intracellular thyroid hormone signaling during cellular differentiation M Dentice, A Marsili, AM Zavacki, PR Larsen, D Salvatore Biochimica et Biophysica Acta (BBA)-General Subjects 1830 (7), 3937-3945, 2013 | 173 | 2013 |
Thyroid hormone promotes postnatal rat pancreatic β-cell development and glucose-responsive insulin secretion through MAFA C Aguayo-Mazzucato, AM Zavacki, A Marinelarena, J Hollister-Lock, ... Diabetes 62 (5), 1569-1580, 2013 | 170 | 2013 |
Deubiquitination of type 2 iodothyronine deiodinase by von Hippel–Lindau protein–interacting deubiquitinating enzymes regulates thyroid hormone activation C Curcio-Morelli, AM Zavacki, M Christofollete, B Gereben, ... The Journal of clinical investigation 112 (2), 189-196, 2003 | 159 | 2003 |
Type 1 iodothyronine deiodinase is a sensitive marker of peripheral thyroid status in the mouse AM Zavacki, H Ying, MA Christoffolete, G Aerts, E So, JW Harney, ... Endocrinology 146 (3), 1568-1575, 2005 | 150 | 2005 |
Protein discharge from immature secretory granules displays both regulated and constitutive characteristics P Arvan, R Kuliawat, D Prabakaran, AM Zavacki, D Elahi, S Wang, ... Journal of Biological Chemistry 266 (22), 14171-14174, 1991 | 148 | 1991 |
Role of the iodothyronine deiodinases in the physiology and pathophysiology of thyroid hormone action PR Larsen, AM Zavacki European thyroid journal 1 (4), 232-242, 2013 | 135 | 2013 |
The arrestin domain-containing 3 protein regulates body mass and energy expenditure P Patwari, V Emilsson, EE Schadt, WA Chutkow, S Lee, A Marsili, ... Cell metabolism 14 (5), 671-683, 2011 | 133 | 2011 |
Ubiquitination-induced conformational change within the deiodinase dimer is a switch regulating enzyme activity GDV Sagar, B Gereben, I Callebaut, JP Mornon, A Zeöld, WS da Silva, ... Molecular and cellular biology 27 (13), 4774-4783, 2007 | 127 | 2007 |
Mice with a targeted deletion of the type 2 deiodinase are insulin resistant and susceptible to diet induced obesity A Marsili, C Aguayo-Mazzucato, T Chen, A Kumar, M Chung, EP Lunsford, ... PloS one 6 (6), e20832, 2011 | 118 | 2011 |
Activation of the orphan receptor RIP14 by retinoids AM Zavacki, JM Lehmann, W Seol, TM Willson, SA Kliewer, DD Moore Proceedings of the National Academy of Sciences 94 (15), 7909-7914, 1997 | 115 | 1997 |