A near-IR uncaging strategy based on cyanine photochemistry AP Gorka, RR Nani, J Zhu, S Mackem, MJ Schnermann Journal of the American Chemical Society 136 (40), 14153-14159, 2014 | 249 | 2014 |
Quinoline drug–heme interactions and implications for antimalarial cytostatic versus cytocidal activities AP Gorka, A de Dios, PD Roepe Journal of medicinal chemistry 56 (13), 5231-5246, 2013 | 197 | 2013 |
Near‐IR light‐mediated cleavage of antibody–drug conjugates using cyanine photocages RR Nani, AP Gorka, T Nagaya, H Kobayashi, MJ Schnermann Angewandte Chemie International Edition 54 (46), 13635-13638, 2015 | 182 | 2015 |
Cyanine polyene reactivity: scope and biomedical applications AP Gorka, RR Nani, MJ Schnermann Organic & biomolecular chemistry 13 (28), 7584-7598, 2015 | 164 | 2015 |
In Vivo Activation of Duocarmycin–Antibody Conjugates by Near-Infrared Light RR Nani, AP Gorka, T Nagaya, T Yamamoto, J Ivanic, H Kobayashi, ... ACS central science 3 (4), 329-337, 2017 | 137 | 2017 |
Harnessing cyanine reactivity for optical imaging and drug delivery AP Gorka, RR Nani, MJ Schnermann Accounts of chemical research 51 (12), 3226-3235, 2018 | 119 | 2018 |
Anti-plasmodial polyvalent interactions in Artemisia annua L. aqueous extract–possible synergistic and resistance mechanisms JO Suberu, AP Gorka, L Jacobs, PD Roepe, N Sullivan, GC Barker, ... PloS one 8 (11), e80790, 2013 | 101 | 2013 |
Harnessing cyanine photooxidation: from slowing photobleaching to near-IR uncaging AP Gorka, MJ Schnermann Current Opinion in Chemical Biology 33, 117-125, 2016 | 85 | 2016 |
Glypican‐3‐specific antibody drug conjugates targeting hepatocellular carcinoma Y Fu, DJ Urban, RR Nani, YF Zhang, N Li, H Fu, H Shah, AP Gorka, ... Hepatology 70 (2), 563-576, 2019 | 73 | 2019 |
An intrinsically disordered peptide facilitates non‐endosomal cell entry SH Medina, SE Miller, AI Keim, AP Gorka, MJ Schnermann, JP Schneider Angewandte Chemie 128 (10), 3430-3433, 2016 | 67 | 2016 |
Near-infrared uncaging or photosensitizing dictated by oxygen tension ED Anderson, AP Gorka, MJ Schnermann Nature Communications 7 (1), 13378, 2016 | 66 | 2016 |
Role of fluorophore charge on the in vivo optical imaging properties of near-infrared cyanine dye/monoclonal antibody conjugates K Sato, AP Gorka, T Nagaya, MS Michie, RR Nani, Y Nakamura, VL Coble, ... Bioconjugate chemistry 27 (2), 404-413, 2016 | 65 | 2016 |
The hydroxyl functionality and a rigid proximal N are required for forming a novel non-covalent quinine-heme complex JN Alumasa, AP Gorka, LB Casabianca, E Comstock, AC De Dios, ... Journal of inorganic biochemistry 105 (3), 467-475, 2011 | 62 | 2011 |
Antiproliferative and Antiplasmodial Dimeric Phloroglucinols from Mallotus oppositifolius from the Madagascar Dry Forest L Harinantenaina, JD Bowman, PJ Brodie, C Slebodnick, MW Callmander, ... Journal of natural products 76 (3), 388-393, 2013 | 55 | 2013 |
Cytostatic versus cytocidal activities of chloroquine analogues and inhibition of hemozoin crystal growth AP Gorka, JN Alumasa, KS Sherlach, LM Jacobs, KB Nickley, JP Brower, ... Antimicrobial agents and chemotherapy 57 (1), 356-364, 2013 | 54 | 2013 |
Investigating the activity of quinine analogues versus chloroquine resistant Plasmodium falciparum T Dinio, AP Gorka, A McGinniss, PD Roepe, JB Morgan Bioorganic & medicinal chemistry 20 (10), 3292-3297, 2012 | 54 | 2012 |
Electrophile-Integrating Smiles Rearrangement Provides Previously Inaccessible C4′-O-Alkyl Heptamethine Cyanine Fluorophores RR Nani, JB Shaum, AP Gorka, MJ Schnermann Organic letters 17 (2), 302-305, 2015 | 52 | 2015 |
Impact of C4′-O-Alkyl Linker on in Vivo Pharmacokinetics of Near-Infrared Cyanine/Monoclonal Antibody Conjugates K Sato, T Nagaya, Y Nakamura, T Harada, RR Nani, JB Shaum, AP Gorka, ... Molecular pharmaceutics 12 (9), 3303-3311, 2015 | 41 | 2015 |
Effect of charge localization on the in vivo optical imaging properties of near-infrared cyanine dye/monoclonal antibody conjugates K Sato, AP Gorka, T Nagaya, MS Michie, Y Nakamura, RR Nani, VL Coble, ... Molecular BioSystems 12 (10), 3046-3056, 2016 | 37 | 2016 |
Cytostatic versus cytocidal profiling of quinoline drug combinations via modified fixed-ratio isobologram analysis AP Gorka, LM Jacobs, PD Roepe Malaria journal 12, 1-9, 2013 | 37 | 2013 |