Synthesis and biological evaluation of novel macrocyclic ligands with pendent donor groups as potential yttrium chelators for radioimmunotherapy with improved complex formation … H Chong, K Garmestani, D Ma, DE Milenic, T Overstreet, MW Brechbiel Journal of medicinal chemistry 45 (16), 3458-3464, 2002 | 92 | 2002 |
Evaluation of binding selectivities of caged crown ligands toward heavy metals by electrospray ionization/quadrupole ion trap mass spectrometry SM Blair, JS Brodbelt, AP Marchand, KA Kumar, HS Chong Analytical chemistry 72 (11), 2433-2445, 2000 | 85 | 2000 |
Synthesis and Preclinical Evaluation of Bifunctional Ligands for Improved Chelation Chemistry of 90Y and 177Lu for Targeted Radioimmunotherapy CS Kang, X Sun, F Jia, HA Song, Y Chen, M Lewis, HS Chong Bioconjugate chemistry 23 (9), 1775-1782, 2012 | 83 | 2012 |
Synthesis and alkali metal picrate extraction capabilities of novel, cage-functionalized, pyridine containing crown ethers and cryptands AP Marchand, HS Chong, S Alihodz, WH Watson, SG Bodige Tetrahedron 55 (32), 9687-9696, 1999 | 75* | 1999 |
Novel bimodal bifunctional ligands for radioimmunotherapy and targeted MRI HS Chong, HA Song, X Ma, D E. Milenic, E D. Brady, S Lim, H Lee, ... Bioconjugate chemistry 19 (7), 1439-1447, 2008 | 59 | 2008 |
Development of a spectroscopic assay for bifunctional ligand-protein conjugates based on copper ED Brady, HS Chong, DE Milenic, MW Brechbiel Nuclear medicine and biology 31 (6), 795-802, 2004 | 59 | 2004 |
Efficient synthesis and evaluation of bimodal ligand NETA HS Chong, HA Song, N Birch, T Le, S Lim, X Ma Bioorganic & medicinal chemistry letters 18 (11), 3436-3439, 2008 | 56 | 2008 |
Preclinical evaluation of NETA-based bifunctional ligand for radioimmunotherapy applications using 212Bi and 213Bi: radiolabeling, serum stability, and biodistribution and … CS Kang, HA Song, DE Milenic, KE Baidoo, MW Brechbiel, HS Chong Nuclear medicine and biology 40 (5), 600-605, 2013 | 53 | 2013 |
Efficient Bifunctional Decadentate Ligand 3p-C-DEPA for Targeted α-Radioimmunotherapy Applications HA Song, CS Kang, KE Baidoo, DE Milenic, Y Chen, A Dai, MW Brechbiel, ... Bioconjugate chemistry 22 (6), 1128-1135, 2011 | 52 | 2011 |
In vitro and in vivo evaluation of novel ligands for radioimmunotherapy HS Chong, DE Milenic, K Garmestani, ED Brady, H Arora, C Pfiester, ... Nuclear medicine and biology 33 (4), 459-467, 2006 | 51 | 2006 |
Rational design and generation of a bimodal bifunctional ligand for antibody-targeted radiation cancer therapy HS Chong, X Ma, T Le, B Kwamena, DE Milenic, ED Brady, HA Song, ... Journal of medicinal chemistry 51 (1), 118-125, 2008 | 50 | 2008 |
Synthesis and evaluation of novel macrocyclic and acyclic ligands as contrast enhancement agents for magnetic resonance imaging HS Chong, K Garmestani, LH Bryant, DE Milenic, T Overstreet, N Birch, ... Journal of medicinal chemistry 49 (6), 2055-2062, 2006 | 50 | 2006 |
Promising bifunctional chelators for copper 64-PET imaging: practical 64Cu radiolabeling and high in vitro and in vivo complex stability N Wu, CS Kang, I Sin, S Ren, D Liu, VC Ruthengael, MR Lewis, ... JBIC Journal of Biological Inorganic Chemistry 21, 177-184, 2016 | 48 | 2016 |
Copper-64 radiolabeling and biological evaluation of bifunctional chelators for radiopharmaceutical development RA De Silva, S Jain, KA Lears, HS Chong, CS Kang, X Sun, BE Rogers Nuclear medicine and biology 39 (8), 1099-1104, 2012 | 48 | 2012 |
Synthesis of a novel cage-functionalized chiral binaphthol host: a potential new agent for enantioselective recognition of chiral ammonium salts AP Marchand, HS Chong, B Ganguly Tetrahedron: Asymmetry 10 (24), 4695-4700, 1999 | 48 | 1999 |
Evaluation of alkali metal binding selectivities of caged aza-crown ether ligands by microelectrospray ionization/quadrupole ion trap mass spectrometry SM Blair, JS Brodbelt, AP Marchand, HS Chong, S Alihodžić Journal of the American Society for Mass Spectrometry 11 (10), 884-891, 2000 | 46 | 2000 |
Synthesis of therapeutic and diagnostic drugs centered on regioselective and stereoselective ring opening of aziridinium ions HS Chong US Patent 9,446,995, 2016 | 42 | 2016 |
Synthesis and evaluation of a new bifunctional NETA chelate for molecular targeted radiotherapy using90Y or177Lu CS Kang, Y Chen, H Lee, D Liu, X Sun, J Kweon, MR Lewis, HS Chong Nuclear medicine and biology 42 (3), 242-249, 2015 | 41 | 2015 |
Iron chelators as therapeutic iron depletion agents N Birch, X Wang, HS Chong Expert Opinion on Therapeutic Patents 16 (11), 1533-1556, 2006 | 41 | 2006 |
Synthesis of DTPA analogues derived from piperidine and azepane: potential contrast enhancement agents for magnetic resonance imaging HS Chong, K Garmestani, LH Bryant, MW Brechbiel The Journal of Organic Chemistry 66 (23), 7745-7750, 2001 | 40 | 2001 |