| Mitochondrial impairment in microglia amplifies NLRP3 inflammasome proinflammatory signaling in cell culture and animal models of Parkinson’s disease S Sarkar, E Malovic, DS Harishchandra, S Ghaisas, N Panicker, A Charli, ... npj Parkinson's Disease 3 (1), 30, 2017 | 228 | 2017 |
| Fyn kinase regulates misfolded α-synuclein uptake and NLRP3 inflammasome activation in microglia N Panicker, S Sarkar, DS Harischandra, M Neal, TI Kam, H Jin, ... Journal of Experimental Medicine 216 (6), 1411-1430, 2019 | 198 | 2019 |
| Fyn kinase regulates microglial neuroinflammatory responses in cell culture and animal models of Parkinson's disease N Panicker, H Saminathan, H Jin, M Neal, DS Harischandra, R Gordon, ... Journal of Neuroscience 35 (27), 10058-10077, 2015 | 150 | 2015 |
| Manganese promotes the aggregation and prion-like cell-to-cell exosomal transmission of α-synuclein DS Harischandra, D Rokad, ML Neal, S Ghaisas, S Manne, S Sarkar, ... Science signaling 12 (572), eaau4543, 2019 | 148 | 2019 |
| Manganese exposure induces neuroinflammation by impairing mitochondrial dynamics in astrocytes S Sarkar, E Malovic, DS Harischandra, HA Ngwa, A Ghosh, C Hogan, ... Neurotoxicology 64, 204-218, 2018 | 128 | 2018 |
| Manganese activates NLRP3 inflammasome signaling and propagates exosomal release of ASC in microglial cells S Sarkar, D Rokad, E Malovic, J Luo, DS Harischandra, H Jin, ... Science Signaling 12 (563), eaat9900, 2019 | 117 | 2019 |
| Mito-apocynin prevents mitochondrial dysfunction, microglial activation, oxidative damage, and progressive neurodegeneration in MitoPark transgenic mice M Langley, A Ghosh, A Charli, S Sarkar, M Ay, J Luo, J Zielonka, T Brenza, ... Antioxidants & redox signaling 27 (14), 1048-1066, 2017 | 116 | 2017 |
| Prokineticin‐2 promotes chemotaxis and alternative A2 reactivity of astrocytes M Neal, J Luo, DS Harischandra, R Gordon, S Sarkar, H Jin, ... Glia 66 (10), 2137-2157, 2018 | 104 | 2018 |
| Protein kinase Cδ upregulation in microglia drives neuroinflammatory responses and dopaminergic neurodegeneration in experimental models of Parkinson's disease R Gordon, N Singh, V Lawana, A Ghosh, DS Harischandra, H Jin, ... Neurobiology of disease 93, 96-114, 2016 | 99 | 2016 |
| Organophosphate pesticide chlorpyrifos impairs STAT1 signaling to induce dopaminergic neurotoxicity: Implications for mitochondria mediated oxidative stress signaling events N Singh, V Lawana, J Luo, P Phong, A Abdalla, B Palanisamy, D Rokad, ... Neurobiology of disease 117, 82-113, 2018 | 95 | 2018 |
| Kv1. 3 modulates neuroinflammation and neurodegeneration in Parkinson’s disease S Sarkar, HM Nguyen, E Malovic, J Luo, M Langley, BN Palanisamy, ... The Journal of Clinical Investigation 130 (8), 4195-4212, 2020 | 92 | 2020 |
| The Parkinson’s disease protein alpha-synuclein is a modulator of processing bodies and mRNA stability E Hallacli, C Kayatekin, S Nazeen, XH Wang, Z Sheinkopf, ... Cell 185 (12), 2035-2056. e33, 2022 | 71 | 2022 |
| Involvement of c-Abl kinase in microglial activation of NLRP3 inflammasome and impairment in autolysosomal system V Lawana, N Singh, S Sarkar, A Charli, H Jin, V Anantharam, ... Journal of Neuroimmune Pharmacology 12, 624-660, 2017 | 70 | 2017 |
| Molecular signatures of neuroinflammation induced by αsynuclein aggregates in microglial cells S Sarkar, EB Dammer, E Malovic, AL Olsen, SA Raza, T Gao, H Xiao, ... Frontiers in immunology 11, 33, 2020 | 66 | 2020 |
| Role of the Fyn-PKCδ signaling in SE-induced neuroinflammation and epileptogenesis in experimental models of temporal lobe epilepsy S Sharma, S Carlson, S Puttachary, S Sarkar, L Showman, M Putra, ... Neurobiology of disease 110, 102-121, 2018 | 59 | 2018 |
| α-synuclein impairs autophagosome maturation through abnormal actin stabilization S Sarkar, AL Olsen, K Sygnecka, KM Lohr, MB Feany PLoS genetics 17 (2), e1009359, 2021 | 54 | 2021 |
| MitoPark transgenic mouse model recapitulates the gastrointestinal dysfunction and gut-microbiome changes of Parkinson’s disease S Ghaisas, MR Langley, BN Palanisamy, S Dutta, K Narayanaswamy, ... Neurotoxicology 75, 186-199, 2019 | 38 | 2019 |
| Characterization and comparative analysis of a new mouse microglial cell model for studying neuroinflammatory mechanisms during neurotoxic insults S Sarkar, E Malovic, D Sarda, V Lawana, D Rokad, H Jin, V Anantharam, ... Neurotoxicology 67, 129-140, 2018 | 28 | 2018 |
| Cobinamide is effective for treatment of hydrogen sulfide–induced neurological sequelae in a mouse model P Anantharam, EM Whitley, B Mahama, DS Kim, S Sarkar, C Santana, ... Annals of the New York Academy of Sciences 1408 (1), 61-78, 2017 | 22 | 2017 |
| Rapid and refined CD11b magnetic isolation of primary microglia with enhanced purity and versatility S Sarkar, E Malovic, B Plante, G Zenitsky, H Jin, V Anantharam, ... JoVE (Journal of Visualized Experiments), e55364, 2017 | 22 | 2017 |
Anumantha KanthasamyProfessor of Biomedical Sciences, Iowa State UniversityVerified email at iastate.edu
